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Mast cells in synovial tissue may explain why women report worse osteoarthritis pain than men

Investigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have significantly increased levels of immune cells called mast cells in synovial tissue surrounding the knee joint than men.

14 Nov 2022

New discovery reveals which patients will survive longer after receiving immunotherapy

Patients with head and neck cancer who have more genetic material on chromosome 9 in their cancer cells survive three times longer after receiving immunotherapy than those with less genetic material there, a new study finds.

14 Nov 2022

Unique peptides with anti-cancer potential discovered

A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.

14 Nov 2022

Researchers provide new insights into the vexing process that makes HIV stealthy

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report.

14 Nov 2022

Novel drug could help to fight both COVID-19 and cancer

While vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains of the virus arise that could bypass vaccine protection.

14 Nov 2022

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

A new paper introduces evidence of effective alleviation of disease severity using intravenous immunoglobulin (IVIg).

14 Nov 2022

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

Researchers investigated the early T cell responses during SARS-CoV-2 infections to understand the mechanisms of rapid clonal expansion that characterize the T cell responses to acute infections and vaccinations.

14 Nov 2022

What is the role of macrophage origin, function, and heterogeneity in health and disease?

In a new study, researchers examined the wealth of information available regarding the heterogeneity of tissue macrophages.

14 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

SARS-CoV-2 detected in white-tailed deer in Canada

Researchers investigated the detection of SARS-CoV-2 in white-tailed deer.

14 Nov 2022

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Following ELRIG 2022, News-Medical speaks with Cancer Research Horizons, the innovation engine of Cancer Research UK about their efforts to advance the drug discovery sector.

From Cancer Research UK 14 Nov 2022

The viral fitness and antigenic relationship among Omicron sublineages

Researchers used mouse models and human airway cell cultures to investigate the relative viral replication rates and cross-neutralization against SARS-CoV-2 Omicron sublineages.

14 Nov 2022

World Diabetes Day 2022: The Importance of Type 1 Research and Awareness with JDRF

For World Diabetes Day 2022, News-Medical speaks to JDRF, the type 1 diabetes charity, about the importance of type 1 diabetes research and awareness, as well as dispelling the misconceptions behind this autoimmune condition.

14 Nov 2022

Reversing paralysis with electrical stimulation of neurons

In a recent study published in the Nature journal, researchers assessed the impact of spatiotemporal epidural electrical stimulation (EES) on individuals suffering from chronic spinal cord damage.

13 Nov 2022

How mRNA vaccines work without an added adjuvant

In a recent study published in the Immunity journal, researchers explored the current knowledge of the mechanism employed by messenger ribonucleic acid (mRNA) vaccines to elicit innate immune activation.

13 Nov 2022

How air pollution affects the central nervous system over time

An article published in the journal Toxics describes how air pollutants adversely impact the human nervous system.

13 Nov 2022

Can monkeypox infection lead to myocarditis?

A recent study presents the first known case of myocarditis as a complication of monkeypox virus infection.

13 Nov 2022

Study finds no differences in CAR T-cell therapy outcomes among pediatric ALL patients across different socioeconomic levels

Social determinants of health affect the outcomes of many illnesses, and pediatric cancer is no exception. In fact, children with acute lymphoblastic leukemia (ALL) living in poverty are significantly more likely to relapse and die from their disease than those from wealthier backgrounds.

11 Nov 2022

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

A multidisciplinary team of Weill Cornell Medicine researchers have received a five-year $5.7 million grant from the National Cancer Institute at the National Institutes of Health to fund a center aimed at developing messenger RNA (mRNA) vaccines to deter cancer development in at-risk groups.

11 Nov 2022

New research finds dynamic electrical signatures of breast cancer cells

New research has found variable voltages in the membranes of breast cancer cells, revealing clues about how they grow and spread.

11 Nov 2022

B Cell News and Research

Mast cells in synovial tissue may explain why women report worse osteoarthritis pain than men

New discovery reveals which patients will survive longer after receiving immunotherapy

Unique peptides with anti-cancer potential discovered

Researchers provide new insights into the vexing process that makes HIV stealthy

Novel drug could help to fight both COVID-19 and cancer

Blood samples from healthy individuals have pre-existing anti-SARS-CoV-2 IgGs and IVIg may be an effective therapy for severe COVID-19

Study suggests the rapid expansion of naïve T cells can provide a fast and effective immune response to SARS-CoV-2 and other viral infections

What is the role of macrophage origin, function, and heterogeneity in health and disease?

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

SARS-CoV-2 detected in white-tailed deer in Canada

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

The viral fitness and antigenic relationship among Omicron sublineages

World Diabetes Day 2022: The Importance of Type 1 Research and Awareness with JDRF

Reversing paralysis with electrical stimulation of neurons

How mRNA vaccines work without an added adjuvant

How air pollution affects the central nervous system over time

Can monkeypox infection lead to myocarditis?

Study finds no differences in CAR T-cell therapy outcomes among pediatric ALL patients across different socioeconomic levels

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

New research finds dynamic electrical signatures of breast cancer cells

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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