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Researchers identify steps by which cell removes RNA from cytoplasm

RNA encodes the proteins that play a key role in cellular reproduction, but the manner in which cells regulate its removal once these proteins are synthesized remains a mystery. One piece of this mystery has been solved as researchers at the University of North Carolina at Chapel Hill who have identified the steps by which a cell removes RNA from the cytoplasm.

21 Mar 2014

Researchers identify genetic defect that causes a subset of irritable bowel syndrome

Is irritable bowel syndrome (IBS) caused by genetics, diet, past trauma, anxiety? All are thought to play a role, but now, for the first time, researchers have reported a defined genetic defect that causes a subset of IBS. The research was published in the journal Gastroenterology.

21 Mar 2014

New tool pinpoints genetic sources of disease

Many diseases are the result of either variations in the genome or reversible chemical changes to DNA, known as the epigenome. New data obtained by Johns Hopkins scientists show a connection between genetic variants and epigenetic information.

20 Mar 2014

Preterm babies' guts harbor infectious microbes that can cause late-onset sepsis

Babies born prematurely are surviving in increasing numbers. But many withstand complications of early birth only to suffer late-onset sepsis - life-threatening bloodstream infections that strike after infants reach 72 hours of age.

20 Mar 2014

Scientists describe gut bacteria that cause sepsis in preterm infants

Researchers studying intestinal bacteria in newborns have characterized the gut bacteria of premature infants who go on to develop sepsis, a serious and potentially life-threatening condition caused by bacteria in the bloodstream.

19 Mar 2014

Two new risk loci for bipolar disorder identified

Researchers have found two new risk loci for bipolar disorder in a genome-wide association study of 2.3 million single-nucleotide polymorphisms.

19 Mar 2014

Restless legs syndrome alters expression of critical gene during fetal development of brain

In a study published online in Genome Research, researchers of the Helmholtz Zentrum München und the Technische Universität München have demonstrated that a common genetic variant associated with Restless Legs Syndrome (RLS) alters the expression of a critical gene during fetal development of the brain.

19 Mar 2014

USTAR Center for Genetic Discovery to integrate genome data with patient care

The USTAR Center for Genetic Discovery is partnering with California based Omicia, Inc, to make analyzing a patient's genome as routine as performing a blood test.

19 Mar 2014

Higher genetic risk of obesity may amplify effects of fried food consumption on body weight

People with a genetic predisposition to obesity are at a higher risk of obesity and related chronic diseases from eating fried foods than those with a lower genetic risk, according to a new study from researchers from Harvard School of Public Health, Brigham and Women's Hospital, and Harvard Medical School.

19 Mar 2014

Sequencing reveals genetic diversity in hospital-acquired bacterium

Using genome sequencing, National Institutes of Health scientists and their colleagues have tracked the evolution of the antibiotic-resistant bacterium Klebsiella pneumoniae sequence type 258 (ST258), an important agent of hospital-acquired infections.

18 Mar 2014

Vitamin D receptor gene variant protects against male LUTS

An international research effort aimed at identifying the genetic basis of lower urinary tract symptoms has identified five candidate genes, one of which – encoding the vitamin D receptor – is consistently protective against these symptoms in men.

17 Mar 2014

S. pneumoniae thrives in human saliva

Streptococcus pneumoniae is able to survive and thrive in human saliva, Dutch researchers have shown.

17 Mar 2014

Findings reveal potential drug targets for small cell lung cancer

Cancer cells undergo extensive genetic alterations as they grow and spread through the body. Some of these mutations, known as "drivers," help spur cells to grow out of control, while others ("passengers") are merely along for the ride.

17 Mar 2014

Biomedical scientist to receive Chen Award for distinguished achievement in genetic and genomic research

The international Human Genome Organization (HUGO) will present its top award to Jackson Laboratory President and CEO Edison Liu, M.D.

17 Mar 2014

Patient with advanced bladder cancer shows complete response to everolimus and pazopanib drugs

A patient with advanced bladder cancer experienced a complete response for 14 months to the drug combination everolimus and pazopanib in a phase I trial, and genomic profiling of his tumor revealed two alterations that may have caused this exceptional response, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

13 Mar 2014

Study: Musical aptitude is affected by a combination of genes involved in auditory pathway

Multiple regions in the human genome are reported to be linked to musical aptitude, according to a study published this week in Molecular Psychiatry.

13 Mar 2014

Researchers identify new player in onset and progression of heart failure

A team of cardiovascular researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai, Sanford-Burnham Medical Research Institute, and University of California, San Diego have identified a small, but powerful, new player in the onset and progression of heart failure.

13 Mar 2014

Precision and Agrivida enter into trait development collaboration based on precise gene modifications

Precision BioSciences and Agrivida revealed today that they have entered into a trait development collaboration based on precise gene modifications made possible by Precision's Directed Nuclease Editor (DNE) Technology.

12 Mar 2014

Three innovative tools to detect, test and initiate personalized drug treatment for seizures

A team of researchers from the National Institutes of Health, Emory University and Cedars-Sinai - specialists in identifying and treating very rare diseases - used three innovative tools to detect a previously unknown gene mutation, test potential therapies in the lab, and initiate personalized drug treatment for a boy with a lifelong history of uncontrollable seizures that caused significant impact on his cognitive and social development.

12 Mar 2014

Researchers explore how genetics affects causes and prevalence of preterm birth

More than 450,000 babies are born too soon each year in the U.S. Preterm birth is a serious health problem that costs the nation more than $26 billion annually, according to the Institute of Medicine, and is the leading cause of newborn death.

12 Mar 2014

Genome News and Research

Researchers identify steps by which cell removes RNA from cytoplasm

Researchers identify genetic defect that causes a subset of irritable bowel syndrome

New tool pinpoints genetic sources of disease

Preterm babies' guts harbor infectious microbes that can cause late-onset sepsis

Scientists describe gut bacteria that cause sepsis in preterm infants

Two new risk loci for bipolar disorder identified

Restless legs syndrome alters expression of critical gene during fetal development of brain

USTAR Center for Genetic Discovery to integrate genome data with patient care

Higher genetic risk of obesity may amplify effects of fried food consumption on body weight

Sequencing reveals genetic diversity in hospital-acquired bacterium

Vitamin D receptor gene variant protects against male LUTS

S. pneumoniae thrives in human saliva

Findings reveal potential drug targets for small cell lung cancer

Biomedical scientist to receive Chen Award for distinguished achievement in genetic and genomic research

Patient with advanced bladder cancer shows complete response to everolimus and pazopanib drugs

Study: Musical aptitude is affected by a combination of genes involved in auditory pathway

Researchers identify new player in onset and progression of heart failure

Precision and Agrivida enter into trait development collaboration based on precise gene modifications

Three innovative tools to detect, test and initiate personalized drug treatment for seizures

Researchers explore how genetics affects causes and prevalence of preterm birth

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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