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New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Multiple sclerosis is an autoimmune disease that affects more than 2.3 million people worldwide. This debilitating condition periodically shutters communication between the brain and other parts of the body, resulting in symptoms that range from numbness and tingling in the arms and legs to blindness and paralysis.

22 Feb 2019

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

Patients with Duchenne muscular dystrophy (DMD) have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

21 Feb 2019

Behavior change of prolonged smoking cessation may delay or prevent onset of seropositive rheumatoid arthritis

In an Arthritis Care & Research analysis of 230,732 women, those who quit smoking many years ago had a lower risk of a certain form of rheumatoid arthritis (RA) compared with women who recently quit.

21 Feb 2019

Sustained smoking cessation can lower risk of seropositive RA

Smoking is an important risk factor for developing the most common form of rheumatoid arthritis and other inflammatory diseases, but a critical question remains: Can those who quit smoking delay or prevent RA or have they permanently and irrevocably altered their risk of the disease? A new study by investigators from Brigham and Women's Hospital leverages data from the Nurses' Health Studies to find out.

21 Feb 2019

New sepsis test could save thousands of lives

Researchers have used a biosensor that can quickly identify biomarkers of sepsis and has the potential to save thousands of lives.

21 Feb 2019

Johns Hopkins scientists find new compound that may prevent reperfusion injury

In a strategic search, Johns Hopkins scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they found one that may prevent reperfusion injury, a tissue-damaging and common complication of surgery, heart attack and stroke.

21 Feb 2019

Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A Salk Institute discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead to a treatment for Alzheimer's disease based on a compound found in nature.

21 Feb 2019

Peripheral nerve injury can trigger the onset and spread of ALS, shows study

A growing collection of anecdotal stories raises the possibility that nerve injury in an arm or a leg can act as a trigger for the development amyotrophic lateral sclerosis, or ALS -- a progressive neurodegenerative disease also known as Lou Gehrig's disease, named after the famous New York Yankee who died of it in 1941.

20 Feb 2019

Antipsychotic polypharmacy may be beneficial for schizophrenia patients

Combining certain types of two antipsychotic agents in the maintenance treatment of schizophrenia is associated with a lower risk of relapse than using monotherapy. T

20 Feb 2019

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumors in several mouse models.

20 Feb 2019

Elevated levels of key cellular process implicated in intestinal inflammation and IBD

Elevated levels of the key cellular process of apoptosis have been implicated in intestinal inflammation and inflammatory bowel disease in a new study from the Quadram Institute.

20 Feb 2019

Heavy cigarette smoking could damage vision, say researchers

New research suggests that smoking more than 20 cigarettes a day may damage a person’s vision and disrupt their ability to see colors.

20 Feb 2019

Novel preclinical model mimics persistent interneuron loss seen in preterm infants

Research-clinicians at Children's National Health System have created a novel preclinical model that mimics the persistent interneuron loss seen in preterm human infants, identifying interneuron subtypes that could become future therapeutic targets to prevent or lessen neurodevelopmental risks, the team reports Jan. 31, 2019, in eNeuro.

20 Feb 2019

Researchers explain why T cells lose their protective ability in inflamed tissues

Regulatory T cells make sure that immune responses are not too strong and that inflammation is inhibited. This makes them highly interesting for therapies against inflammatory autoimmune diseases such as multiple sclerosis.

20 Feb 2019

Proper oral hygiene and regular visits to dentist can promote heart health

Proper oral hygiene and regular visits to the dentist can support cardiovascular health. This, in a nutshell, is what dental and heart experts agreed today at a joint workshop in Madrid.

19 Feb 2019

Researchers develop new way to deliver treatment for cartilage regeneration

Researchers from Texas A&M University, led by Dr. Akhilesh K. Gaharwar, have developed a new way to deliver treatment for cartilage regeneration.

19 Feb 2019

Cervical microbiome may influence HPV infection more than previously thought

Infections with a Human Papillomavirus cause 99 percent of cervical cancer cases, and the disease's first sign is often the appearance of precancerous lesions on a woman's cervix. But bacteria may play an important role, too.

19 Feb 2019

Study finds new link between food allergies and multiple sclerosis

Like many other medical conditions, the mechanism of multiple sclerosis remains an enigma--a puzzle composed of complex genetic and environmental factors. A key piece to this puzzle is the immune system, which is also responsible for regulating many other physiological (and pathological) phenomena--including allergies.

19 Feb 2019

New protocol could help physicians to rule out bacterial infections in infants

A new protocol could help emergency room physicians to rule out life-threatening bacterial infections among infants up to 2 months of age who have fevers, potentially eliminating the need for spinal taps, unnecessary antibiotic treatments or expensive hospital stays.

18 Feb 2019

Inflammation News and Research

New study finds how high-fat diets fuel colorectal cancer growth

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

Behavior change of prolonged smoking cessation may delay or prevent onset of seropositive rheumatoid arthritis

Sustained smoking cessation can lower risk of seropositive RA

New sepsis test could save thousands of lives

Johns Hopkins scientists find new compound that may prevent reperfusion injury

Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

Peripheral nerve injury can trigger the onset and spread of ALS, shows study

Antipsychotic polypharmacy may be beneficial for schizophrenia patients

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

Elevated levels of key cellular process implicated in intestinal inflammation and IBD

Heavy cigarette smoking could damage vision, say researchers

Novel preclinical model mimics persistent interneuron loss seen in preterm infants

Researchers explain why T cells lose their protective ability in inflamed tissues

Proper oral hygiene and regular visits to dentist can promote heart health

Researchers develop new way to deliver treatment for cartilage regeneration

Cervical microbiome may influence HPV infection more than previously thought

Study finds new link between food allergies and multiple sclerosis

New protocol could help physicians to rule out bacterial infections in infants

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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