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Lessons learned from COVID-19 pandemic can help confront future epidemics

Where did COVID-19 originate? Prof Angus Dalgleish shows that the virus that emerged in Wuhan, China in 2019 had been modified in a laboratory to make it more infectious (for the construction of a more effective vaccine).

1 Sep 2023

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Amgen today announced the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) will review data supporting the supplemental New Drug Application (sNDA) for the full approval of LUMAKRAS® (sotorasib) for adults with previously treated locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC) at a meeting on Oct. 5, 2023.

From AMGEN 1 Sep 2023

Aligning Rhythms, Defying Alzheimer's: Intermittent Fasting's Role in Combating Alzheimer's Disease Neurodegeneration

News Medical interviewed Dr Paula Desplats, an Associate Professor of Neurosciences at the University of California San Diego.

1 Sep 2023

Discovery could lead to more effective treatments for cancers

Case Western Reserve University biochemical researchers have identified a new function of a key protein that leads to cancer–a finding they believe could lead to more effective treatments for a range of cancers and other diseases.

31 Aug 2023

Unique openings in specific ion channels could lead to development of selective drugs

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge.

31 Aug 2023

New insights into how lung cells detect influenza virus

Researchers from Trinity College Dublin have discovered some new and surprising ways that viral RNA and influenza virus are detected by human lung cells, which has potential implications for treating people affected by such viruses.

31 Aug 2023

Scientists delve deeper into how vaccines work against leishmaniasis

Scientists have established the effectiveness of vaccines they developed to prevent the disfiguring skin disease leishmaniasis in animal studies, and Phase 1 human trial planning is in motion for the most promising candidate.

31 Aug 2023

Is the rapid evolution of SARS-CoV-2 in white-tailed deer complicating our fight against the pandemic?

New study reveals rapid evolution of SARS-CoV-2 in Ohio's white-tailed deer population, with a 25% seroprevalence rate. The findings suggest a significant risk of animal-to-human transmission and indicate the virus evolves faster in deer than in humans.

31 Aug 2023

Coronavirus fusion peptide plays more invasive role in infection than previously thought

Although the COVID-19 pandemic was the first time most of humanity learned of the now infamous disease, the family of coronaviruses was first identified in the mid-1960s.

31 Aug 2023

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

A recent study published in Nature Metabolism has revealed the pathogenic mechanism underlying a rare pediatric neurodegenerative disorder known as mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome.

31 Aug 2023

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, "Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging."

31 Aug 2023

Universal approach could potentially expand CAR T cell therapy to all blood cancers

A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer.

31 Aug 2023

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

A cell contains many specialized subunits, called organelles, that carry out important tasks such as energy generation, protein synthesis, and calcium outflux. But what happens when something goes wrong with one of the organelles?

31 Aug 2023

Electrical noise stimulation boosts math skills in individuals with lower brain excitability

Exciting a brain region using electrical noise stimulation can help improve mathematical learning in those who struggle with the subject, according to a new study from the Universities of Surrey and Oxford, Loughborough University, and Radboud University in The Netherlands.

31 Aug 2023

Cell News and Research

Lessons learned from COVID-19 pandemic can help confront future epidemics

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Aligning Rhythms, Defying Alzheimer's: Intermittent Fasting's Role in Combating Alzheimer's Disease Neurodegeneration

Discovery could lead to more effective treatments for cancers

Unique openings in specific ion channels could lead to development of selective drugs

New insights into how lung cells detect influenza virus

Scientists delve deeper into how vaccines work against leishmaniasis

Is the rapid evolution of SARS-CoV-2 in white-tailed deer complicating our fight against the pandemic?

Coronavirus fusion peptide plays more invasive role in infection than previously thought

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

Universal approach could potentially expand CAR T cell therapy to all blood cancers

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

Electrical noise stimulation boosts math skills in individuals with lower brain excitability

Exploring the role of the metabolic syndrome in individual mechanisms of liver fibrosis

Antioxidants stimulate the formation of new blood vessels in lung cancer tumors

New liquid biopsy technology uses RNA "dark matter" to detect cancer

Scientists discover new microglial population important for memory and learning

The Clinical Importance of Circulating Tumor DNA

Novel non-invasive model may help predict preeclampsia before symptoms

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo