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Research reveals critical immunological axis that triggers cancer-promoting chronic inflammation

A Massachusetts General Hospital research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation.

12 Feb 2019

Study findings hold promise for children with DMD

Prednisone, the current standard of care used to treat kids with Duchenne muscular dystrophy (DMD), reduces chronic inflammation but has harsh side effects.

11 Feb 2019

New target appears to aid recovery after optic nerve trauma

When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report.

11 Feb 2019

Study can have implications in the vaccination policies against Hepatitis A

Researchers of the University of Barcelona have analyzed, with massive sequencing techniques for the first time, the evolution of the Hepatitis A virus with samples from patients.

11 Feb 2019

New heated tobacco device is as toxic as vaping and traditional cigarettes

A new study that directly compares new heated tobacco devices with vaping and traditional cigarettes shows that all three are toxic to human lung cells.

11 Feb 2019

Targeting aging process itself can lead to better and more effective interventions

Medical care for older adults has long focused on preventing and treating chronic diseases and the conditions that come with them.

11 Feb 2019

Unexpected discovery points to potential new treatment for autoimmune disorder

Researchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease.

8 Feb 2019

Researchers report promising advance in the search for new class of antidepressants

In experiments with mice, researchers at Johns Hopkins Medicine report a promising advance in the search for a new class of drugs to treat major depression.

8 Feb 2019

Therapy derived from parasitic worms helps protect against one of chemotherapy's side effects

A therapy derived from the eggs of parasitic worms helps to protect against one of chemotherapy's debilitating side effects by significantly downregulating major proinflammatory pathways and reducing inflammation, indicates the first transcriptome-wide profiling of the bladder during ifosfamide-induced hemorrhagic cystitis.

8 Feb 2019

Experts explore involvement of the gut in Parkinson's disease

There is growing evidence that at least in some patients with Parkinson's disease (PD), the disease may begin in the gut. Writing in a special supplement to the Journal of Parkinson's Disease, experts explore the last two decades of research about the gut-brain axis in PD and look ahead at the possible development and impact of these research areas in the next two decades.

8 Feb 2019

Compounds found in fish oil may prevent pregnancy complications, finds study

Compounds found in fish oil prevent pregnancy complications, including preterm birth, neonatal death, and stillbirth, in mice when the complications are caused by a common oral bacteria, according to research published today in the journal JCI Insight.

8 Feb 2019

Researchers reveal novel computational tool used to analyze genetic variation

The field of genetic sequencing has undergone a dramatic revolution over the past 20 years. In 2001 the first copy of the three billion base pairs that assemble the human genome was published.

8 Feb 2019

Blood-clotting factor may cause Alzheimer's disease

A protein known for its role in forming blood clots has been found to cause the characteristic cognitive decline of Alzheimer's disease.

7 Feb 2019

NSAID pretreatment promotes cardiorenal syndrome in heart failure

Non-steroidal anti-inflammatory drugs, or NSAIDs, are widely known as pain-killers and can relieve pain and inflammation. However, prolonged use raises the risk of heart and kidney failure events. A heart attack causes death of heart muscle cells by lack of oxygen, and it also significantly injures the kidneys.

7 Feb 2019

Advanced scan shows brain inflammation related to post-treatment Lyme disease syndrome

More than 1 in 10 people successfully treated with antibiotics for Lyme disease go on to develop chronic, sometimes debilitating, and poorly understood symptoms of fatigue and brain fog that may last for years after their initial infection has cleared up.

6 Feb 2019

Fibrinogen results in cognitive decline in Alzheimer’s disease, finds study

It has long been known that patients with Alzheimer's disease have abnormalities in the vast network of blood vessels in the brain. Some of these alterations may also contribute to age-related cognitive decline in people without dementia.

6 Feb 2019

Research could provide a new way to treat organ scarring in future

The increased deposition of connective tissue is a problem in chronic diseases of many organs such as the lungs, liver, kidneys, gut, and the skin.

6 Feb 2019

Protein CDK6 appears to be key factor in influencing development of MPN

MPNs are a group of rare, malignant diseases of the bone marrow involving the production of an excess of red blood cells, white blood cells and/or platelets.

6 Feb 2019

HIV-1 protein plays broader role in suppressing immune response than thought

Scientists have revealed how a protein produced by HIV-1 plays a broader role in suppressing the immune system's response to infection than previously thought.

6 Feb 2019

Yoga practice decreases severity of rheumatoid arthritis symptoms

According a study published in Restorative Neurology and Neuroscience, eight weeks of intensive yoga practice significantly decreases the severity of physical and psychological symptoms in patients with active rheumatoid arthritis, a debilitating chronic auto-immune inflammatory disease.

5 Feb 2019