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Inflammation increases the expression of risk gene in first-episode schizophrenia patients

Schizophrenia patients have fewer connections between nerve cells. This is believed to be caused by genetic risk variants leading to an excessive elimination of nerve cell connections by the immune cells of the brain.

3 Nov 2022

Researchers shed light on the key functions of innate immune cells

Inflammation and increased mucus production are typical symptoms of worm infections and allergies. This immune response involves our innate immune cells, but their exact functions are not yet fully understood.

3 Nov 2022

Investigating the role of the gut-to-brain axis in defensive responses

In a new study, researchers investigated the function of the gut-to-brain axis in defensive responses induced by toxins.

3 Nov 2022

Gut colonization by proteobacteria modulates mice’s neurobehavioral response to cocaine

A new study revealed that gut colonization by proteobacteria modulates cocaine neurobehavioral response in mice.

3 Nov 2022

New insights into the dynamic inner world of the human immune system

As researchers glean new insights into the dynamic inner world of the human immune system, it has become increasingly clear that mitochondria are critical regulators of how our bodies respond to disease.

3 Nov 2022

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

In a recent study posted to the medRxiv* preprint server, researchers in the United States investigated the source of an enigmatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)-like spike (S) protein strain detected in wastewater but not in clinical samples.

2 Nov 2022

Vimentin is an important co-receptor for SARS-CoV-2 infection

Vimentin functions as a co-receptor for the entry of SARS-CoV-2 into host cells to facilitate infection.

2 Nov 2022

Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

A targeted therapy for children with high-risk Hodgkin lymphoma (HL) was shown to significantly reduce relapse rates when tested in a large multicenter clinical trial conducted by the Children's Oncology Group (COG) and led by pediatric oncologists at Roswell Park Comprehensive Cancer Center, Children's Healthcare of Atlanta and Winship Cancer Institute of Emory University. By combining the targeted antibody-drug conjugate (ADC) brentuximab vedotin (BV) with the standard chemotherapy regimen, children were 10% less likely to relapse.

2 Nov 2022

A portable air sampler to quantify and capture SARS-CoV-2 aerosols in laboratories

Researchers in the United Kingdom evaluated a battery-operated portable air sampler that could recover severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aerosolized in a laboratory using a plaque assay.

2 Nov 2022

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Innate lymphoid cells are a recently discovered family of white blood cells that reside in the skin, gastrointestinal tract, airways and other barrier tissues of the body.

2 Nov 2022

Study uncovers a control hub for skin inflammation

Inflammatory reactions in the skin can reduce damage from UV radiation or infections, but can also result in painful symptoms such as sunburn.

2 Nov 2022

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

Higher viscosity of extracellular fluid enhances cancer dissemination

New research findings show how higher viscosity, or resistance to flow, of the extracellular fluid that surrounds cells enables cancer cells to migrate more rapidly from a primary tumor to other sites in the body.

2 Nov 2022

UC researchers receive NIH grant to study how alcohol, fentanyl affect HIV medications

The United States has set a goal of reducing the number of new HIV infections by 75% by 2025 and by at least 90% by 2030, mirroring the United Nations' initiative to end the AIDS epidemic as a global health threat by 2030.

2 Nov 2022

The importance of accurate pipetting in biomedical laboratory work

In this interview, Stephanie Stursberg, Group Product Manager for pipetting platforms at INTEGRA Biosciences, talks to NewsMedical about the importance of accurate and efficient pipetting in biomedical laboratory work.

From INTEGRA Biosciences 2 Nov 2022

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

A new study aimed to analyze the molecular interactions between the hCypA protein and the SARS-CoV-2 variants to determine the impact of variants on the blocking and binding potential of the hCypA–S protein complex with the ACE2 receptor.

2 Nov 2022

Researchers study the unique adaptability of small intestinal bacteria for the first time

Bacteria in the small intestine adapt dynamically to our nutritional state, with individual species disappearing and reappearing.

1 Nov 2022

New control system could be used to finely tune the production of useful proteins

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

1 Nov 2022

Researchers offer new insights into the neurobiological basis of autism spectrum disorders

Findings from a new study published in Cell Reports, involving a collaborative effort between researchers at the Luikart Laboratory at Dartmouth's Geisel School of Medicine and the Weston Laboratory at the University of Vermont, are providing further insight into the neurobiological basis of autism spectrum disorders (ASD) and pointing to possible treatments.

1 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

B Cell News and Research

Inflammation increases the expression of risk gene in first-episode schizophrenia patients

Researchers shed light on the key functions of innate immune cells

Investigating the role of the gut-to-brain axis in defensive responses

Gut colonization by proteobacteria modulates mice’s neurobehavioral response to cocaine

New insights into the dynamic inner world of the human immune system

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

Vimentin is an important co-receptor for SARS-CoV-2 infection

Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

A portable air sampler to quantify and capture SARS-CoV-2 aerosols in laboratories

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Study uncovers a control hub for skin inflammation

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

Higher viscosity of extracellular fluid enhances cancer dissemination

UC researchers receive NIH grant to study how alcohol, fentanyl affect HIV medications

The importance of accurate pipetting in biomedical laboratory work

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

Researchers study the unique adaptability of small intestinal bacteria for the first time

New control system could be used to finely tune the production of useful proteins

Researchers offer new insights into the neurobiological basis of autism spectrum disorders

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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