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New strategy could increase the effectiveness of chemotherapy treatments

New research led by a team at Massachusetts General Hospital (MGH) points to a promising strategy to boost tumors' intake of cancer drugs, thereby increasing the effectiveness of chemotherapy treatments.

7 May 2021

Study reports vitamin C inhibits SARS-CoV-2 virus main protease

Based on structural analysis, researchers found that vitamin C binds to 3CLpro, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease essential in viral replication. In vitro cell inhibition studies also showed vitamin C could inhibit 3CLpro, indicating a possible new antiviral treatment method.

6 May 2021

Indian SARS-CoV-2 variant shows enhanced host cell entry and immune evasion

A study conducted by researchers in Germany has found that the B.1.617 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has emerged in India entered certain types of lung and intestine cells with slightly increased efficiency compared with the original wild-type strain.

6 May 2021

UMass Amherst researchers achieve breakthrough in the fight against cancer

A team of researchers at the Center for Bioactive Delivery at the University of Massachusetts Amherst's Institute for Applied Life Sciences has engineered a nanoparticle that has the potential to revolutionize disease treatment, including for cancer.

6 May 2021

New method for qualifying safe drug dosing regimens in pediatrics

Determining safe yet effective drug dosages for children is an ongoing challenge for pharmaceutical companies and medical doctors alike.

6 May 2021

This small Canadian drugmaker wants to make J&J vaccines for poor nations. It needs more than a patent waiver.

Biolyse Pharma Corp., which makes a cancer medication, was gearing up to start making generic biologic drugs, made from living organisms. Then the pandemic hit.

6 May 2021

About 84% of antibodies in plasma target non-RBD epitopes on SARS-CoV-2 spike protein, finds study

In a new study recently published in the journal Science, a team of researchers in the U.S. found that most of the antibodies circulating in the blood target areas of the viral spike protein outside the receptor-binding domain (RBD), the part of the spike that binds directly to human cell receptors.

6 May 2021

Many adults with hypertension may be taking other medications that could raise blood pressure

Nearly 1 in 5 adults with high blood pressure, a leading risk factor for heart disease and stroke, also take a medicine that could be elevating their blood pressure, according to new research presented at the American College of Cardiology's 70th Annual Scientific Session.

6 May 2021

Daily intake of two or more sugar-sweetened drinks associated with higher bowel cancer risk

Drinking two or more daily sugar-sweetened beverages in adulthood is linked to a doubling in the risk of bowel cancer before the age of 50--at least in women, finds research published online in the journal Gut.

6 May 2021

Fear of losing employer-sponsored health insurance keeps 1 in 6 workers in their jobs

One out of every six adult workers (16%) in the United States are staying in jobs they might otherwise leave out of fear of losing their employer-sponsored health insurance, according to a new West Health-Gallup survey of more than 3,800 U.S. adults.

6 May 2021

Benefits of drug research are not being shared equitably among study participants, indicates study

A Yale-led study reveals that new medicines and vaccines approved for use in the United States are often unavailable in countries that hosted their clinical trials, suggesting that the benefits of drug research are not being shared equitably among populations that participate in testing.

6 May 2021

Study examines artemisinin-based combination therapy as first-line treatment for malaria

When a mosquito begins to nibble on you, it is not merely feeding on your blood, it is also injecting its saliva into your skin. If that saliva happens to be full of parasites carrying malaria or other diseases from its last victim, then most likely you will become infected, too.

6 May 2021

Study finds no evidence of increased risk for COVID-19 from aspirin/NSAID use

At the beginning of the pandemic, there were concerns over the use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs), increasing the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. NSAIDs are commonly used to treat SARS-CoV-2 infection-related symptoms such as flu and cough and are frequently taken by older adults with multiple health conditions.

6 May 2021

Microneedles for cancer immunotherapy may lead to minimal invasiveness, side effects

A recent study from the University of Helsinki monitors the breakthrough progresses in the development of microneedles for immunotherapy and discusses the challenges regarding their production.

6 May 2021

Study: Second vaccine dose still makes organ transplant recipients vulnerable to COVID-19

In a study published today in the Journal of the American Medical Association (JAMA), Johns Hopkins Medicine researchers show that although two doses of a vaccine against SARS-CoV-2 - the virus that causes COVID 19 - confers some protection for people who have received solid organ transplants, it's still not enough to enable them to dispense with masks, physical distancing and other safety measures.

6 May 2021

FDA outlines inspectional activities during COVID-19 pandemic

Today, the U.S. Food and Drug Administration issued a new report titled, "Resiliency Roadmap for FDA Inspectional Oversight," outlining the agency's inspectional activities during the COVID-19 pandemic and its detailed plan to move toward a more consistent state of operations, including the FDA's priorities related to this work going forward.

6 May 2021

Drugs News and Research

New strategy could increase the effectiveness of chemotherapy treatments

Study reports vitamin C inhibits SARS-CoV-2 virus main protease

Indian SARS-CoV-2 variant shows enhanced host cell entry and immune evasion

UMass Amherst researchers achieve breakthrough in the fight against cancer

New method for qualifying safe drug dosing regimens in pediatrics

This small Canadian drugmaker wants to make J&J vaccines for poor nations. It needs more than a patent waiver.

About 84% of antibodies in plasma target non-RBD epitopes on SARS-CoV-2 spike protein, finds study

Many adults with hypertension may be taking other medications that could raise blood pressure

Daily intake of two or more sugar-sweetened drinks associated with higher bowel cancer risk

Fear of losing employer-sponsored health insurance keeps 1 in 6 workers in their jobs

Benefits of drug research are not being shared equitably among study participants, indicates study

Study examines artemisinin-based combination therapy as first-line treatment for malaria

Study finds no evidence of increased risk for COVID-19 from aspirin/NSAID use

Microneedles for cancer immunotherapy may lead to minimal invasiveness, side effects

Study: Second vaccine dose still makes organ transplant recipients vulnerable to COVID-19

FDA outlines inspectional activities during COVID-19 pandemic

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Covid shot in the arm not enough to keep pharmacies in business

World Asthma Day 2021: How could smart inhalers improve asthma care?

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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