Protein News and Research

RSS

Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

"Selfish chromosomes" explain why most human embryos die very early on, study suggests

New research by a scientist at the Milner Center for Evolution at the University of Bath suggests that "selfish chromosomes" explain why most human embryos die very early on. The study, published in PLoS, Biology, explaining why fish embryos are fine but sadly humans' embryos often don't survive, has implications for the treatment of infertility.

6 Jul 2022

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

When the coronavirus causing COVID-19 infects human cells, the cell's protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, which could increase its ability to infect other cells and to evade antibodies, a new study from the University of Illinois Urbana-Champaign found.

6 Jul 2022

Bone marrow transplants may be an effective treatment for ALS, research suggests

Along with the central nervous system, the immune system may play a fundamental role in Amyotrophic Lateral Sclerosis (ALS), suggesting that bone marrow transplants may be an effective novel treatment for the neurodegenerative disease.

6 Jul 2022

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses.

6 Jul 2022

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available.

5 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

Scientists uncover HIV’s sweet spot

HIV researchers have long been trying to identify the specific cells that the virus prefers to infect and hide in. They know that HIV favors a special type of immune cells called memory CD4 T cells.

5 Jul 2022

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

A study from the National Institutes of Health describes the immune response triggered by COVID-19 infection that damages the brain's blood vessels and may lead to short- and long-term neurological symptoms.

5 Jul 2022

Researchers explore how diet and feeding patterns affect intestinal microbes

An estimated 500 to 1,000 bacterial species reside in each person's gut, perhaps numbering 100,000 trillion microorganisms.

5 Jul 2022

Research uses big data to find cancerous mutations in cells

Artificial intelligence and machine learning are among the latest tools being used by cancer researchers to aid in detection and treatment of the disease.

5 Jul 2022

Study opens up a new avenue for the development of selective drug therapies

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

5 Jul 2022

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

A study conducted at the University of São Paulo in Brazil shows that the synthetic molecule Pep19 acts on the endocannabinoid system, which helps regulate and balance key metabolic functions, such as appetite, fat breakdown (lipolysis), and energy release.

5 Jul 2022

Study identifies a molecule that boosts fat burning

A study led by the University of Bonn has identified a molecule - the purine inosine - that boosts fat burning in brown adipocytes.

5 Jul 2022

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

A new study showed that the newly designed oral nano-in-micro hydrogel delivery platform could be efficiently used to deliver curcumin for the treatment of Ulcerative Colitis.

5 Jul 2022

Human gingival epithelial cells become damaged by cannabis smoke condensate

In a new study, scientists evaluated the effect of cannabis smoke condensate (CSC) on the gingival epithelial cells.

5 Jul 2022

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

In a new study,researchers suggested the inclusion of nucleocapsid protein in vaccines against SARS-CoV-2.

5 Jul 2022

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

In a new study, researchers assessed the influence of severe coronavirus disease 2019 on scrotal infections.

5 Jul 2022

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

In a new study, researchers reported on the non-ACE2 blocking neutralizing antibodies elicited in response to severe coronavirus disease 2019 using deep ribonucleic acid sequencing with >100 million reads per sample and molecular dynamic simulations.

5 Jul 2022

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

In a recent study published in the journal Science Immunology, researchers in the United States described a rare anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) three antibody cocktail IMM-BCP-01.

4 Jul 2022

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires specific interactions between the human protein ZCCHC14 and a group of enzymes called TENT4 poly(A) polymerases.

4 Jul 2022

Protein News and Research

Further Reading

"Selfish chromosomes" explain why most human embryos die very early on, study suggests

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

Bone marrow transplants may be an effective treatment for ALS, research suggests

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

Novel inhalable COVID-19 vaccine

Scientists uncover HIV’s sweet spot

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

Researchers explore how diet and feeding patterns affect intestinal microbes

Research uses big data to find cancerous mutations in cells

Study opens up a new avenue for the development of selective drug therapies

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

Study identifies a molecule that boosts fat burning

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

Human gingival epithelial cells become damaged by cannabis smoke condensate

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

A guide to advancing biotherapeutic research eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo