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Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Whether a melanoma patient will better respond to a single immunotherapy drug or two in combination depends on the abundance of certain white blood cells within their tumors, according to a new study conducted by UC San Francisco researchers joined by physicians from UCSF Health.

20 Jul 2017

Skin-applied microneedle patch boosts immunization to seasonal flu vaccine recipients, study finds

A boosting skin vaccination with a biodegradable microneedle patch and protein constructed from sequences of influenza virus subtypes could improve the effectiveness of conventional influenza vaccines, according to a study led by Georgia State University.

19 Jul 2017

Engineered macrophages invade and engulf tumor cells in mouse models

One reason cancer is so difficult to treat is that it avoids detection by the body. Agents of the immune system are constantly checking the surfaces of cells for chemical signals that say they belong, but cancer cells express the same chemical signals as healthy ones.

19 Jul 2017

Two cell types partner to protect pancreatic tumors from immune attack

Two cell types work together to protect pancreatic tumors from destruction by the immune system. But, blocking this partnership may restore the system's ability to attack these same tumor cells.

19 Jul 2017

Scientists manage to permeate living cells with small antibodies

Scientists at the Technische Universität Darmstadt, Ludwig Maximilians University Munich and the Leibniz Institute for Molecular Pharmacology have managed to introduce tiny antibodies into living cells. The researchers now report on the synthesis and applications for these nanobodies in "Nature Chemistry".

19 Jul 2017

Titanium dioxide nanoparticles can intensify inflammatory reaction in patients with colitis

Titanium dioxide, one of the most-produced nanoparticles worldwide, is being used increasingly in foodstuffs.

19 Jul 2017

Researchers identify new way to increase immune response against cancer and infections

An international research team led by Université de Montréal medical professor Christopher Rudd, director of research in immunology and cell therapy at Maisonneuve-Rosemont Hospital Research Centre, has identified a key new mechanism that regulates the ability of T-cells of the immune system to react against foreign antigens and cancer.

19 Jul 2017

Unique 'Golden Hour' study details ultra-early immune response to trauma

Scientists from the University of Birmingham are carrying out pioneering research as part of a major £10 million study aimed at improving outcomes for patients who have suffered a traumatic injury.

19 Jul 2017

Study shows how omega-3 fatty acids can produce same medicinal qualities as marijuana

Chemical compounds called cannabinoids are found in marijuana and also are produced naturally in the body from omega-3 fatty acids.

18 Jul 2017

Youngest person in U.S. receives full face transplant by Cleveland Clinic team

A team of surgeons and doctors at the Cleveland Clinic made history after operating upon a 21 year old woman for 31 hours to give her a full face transplant. The operation held in May this year was a successful one with the woman receiving a completely new face from a donor.

18 Jul 2017

Research finding could pave way for novel compounds to tackle bacterial resistance

Bacteria or 'superbugs' that have adapted to resist multiple antibiotics are responsible for around 700,000 deaths globally a year; new types of antibiotics are urgently needed.

18 Jul 2017

Study: Breast cancer patients receiving neoadjuvant radiation have lower risk of second primary tumor

Moffitt Cancer Center researchers launched a first of its kind study comparing the long-term benefits of radiation therapy in women with breast cancer either before surgery (neoadjuvant) or after surgery (adjuvant).

17 Jul 2017

Subjective well-being can influence physical health

A new review indicates that subjective well-being—factors such as life satisfaction and enjoyment of life—can influence physical health. The review's investigators also examine why this is so and conditions where it is most likely to occur.

17 Jul 2017

Immune system controls eye tissue regeneration in zebrafish, research finds

Researchers at Johns Hopkins Medicine report evidence that zebrafishes' natural ability to regenerate their eyes' retinal tissue can be accelerated by controlling the fishes' immune systems.

17 Jul 2017

CNIC research holds potential to improve current cancer immunotherapy strategies

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have investigated how different subtypes of essential immune-response cells called CD8+ T lymphocytes cooperate to mount a stronger anti-tumor response.

17 Jul 2017

Southampton researchers find new approach to reverse treatment resistance in lymphoma patients

Researchers from the University of Southampton have identified why some people may become resistant to monoclonal antibodies, a common type of immunotherapy used in lymphoma treatment.

17 Jul 2017

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

A Massachusetts General Hospital research team has identified a novel mechanism behind resistance to angiogenesis inhibitors - drugs that fight cancer by suppressing the formation of new blood vessels.

14 Jul 2017

Feinstein Institute professor finds protein as potential cause for lupus

Leading rheumatologist and Feinstein Institute for Medical Research Professor Betty Diamond, MD, may have identified a protein as a cause for the adverse reaction of the immune system in patients suffering from lupus.

14 Jul 2017

Prior dengue fever in people infected by Zika does not lead to worse illness

Individuals who are infected by Zika virus after having dengue fever do not appear to become more severely ill than people with Zika who have never had dengue.

14 Jul 2017

Scientists uncover new group of Treg cells and DNA features linked to juvenile idiopathic arthritis

A team of scientists and doctors from the SingHealth Duke-NUS Academic Medical Centre has uncovered a new group of regulatory T (Treg) cells and DNA features associated with juvenile idiopathic arthritis (JIA), the most common form of arthritis among children under the age of 16.

14 Jul 2017

Immune System News and Research

Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Skin-applied microneedle patch boosts immunization to seasonal flu vaccine recipients, study finds

Engineered macrophages invade and engulf tumor cells in mouse models

Two cell types partner to protect pancreatic tumors from immune attack

Scientists manage to permeate living cells with small antibodies

Titanium dioxide nanoparticles can intensify inflammatory reaction in patients with colitis

Researchers identify new way to increase immune response against cancer and infections

Unique 'Golden Hour' study details ultra-early immune response to trauma

Study shows how omega-3 fatty acids can produce same medicinal qualities as marijuana

Youngest person in U.S. receives full face transplant by Cleveland Clinic team

Research finding could pave way for novel compounds to tackle bacterial resistance

Study: Breast cancer patients receiving neoadjuvant radiation have lower risk of second primary tumor

Subjective well-being can influence physical health

Immune system controls eye tissue regeneration in zebrafish, research finds

CNIC research holds potential to improve current cancer immunotherapy strategies

Southampton researchers find new approach to reverse treatment resistance in lymphoma patients

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

Feinstein Institute professor finds protein as potential cause for lupus

Prior dengue fever in people infected by Zika does not lead to worse illness

Scientists uncover new group of Treg cells and DNA features linked to juvenile idiopathic arthritis

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