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New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

This week, researchers report new findings that clarify the role of NOD2, a key molecular player in Crohn's Disease, in the cellular signaling pathways that control inflammatory responses. NOD2's clinical relevance is clear from the fact that it is encoded by a Crohn's Disease susceptibility gene.

28 Dec 2004

Evidence suggests that changes in the bacteria and fungi in the gastrointestinal tract can intensify the immune system's reaction to common allergens

If you want to avoid allergies or asthma, scientists at the University of Michigan Medical School suggest you start paying more attention to what's in your gut.

23 Dec 2004

Jumping genes help explain immune system's remarkable ability

A team led by Johns Hopkins scientists has found the first clear evidence that the process behind the human immune system's remarkable ability to recognize and respond to a million different proteins might have originated from a family of genes whose only apparent function is to jump around in genetic material.

22 Dec 2004

Study finds new method can improve chemo survival

Seeking to find a way to lessen patients’ vulnerability to deadly infections following chemotherapy, researchers at the Stanford University School of Medicine have figured out a way to boost the immune function in animals following such treatments.

21 Dec 2004

Study on first new potential drug for tuberculosis in 40 years

454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation, announced today that its proprietary whole genome sequencing technology was used by scientists at Johnson & Johnson Pharmaceutical Research & Development L.L.C. (J&JPRD) to help understand the basis of tuberculosis drug resistance.

20 Dec 2004

Scientists have identified a novel anti-tuberculosis (TB) compound

Scientists at Johnson & Johnson Pharmaceutical Research and Development have identified a novel anti-tuberculosis (TB) compound that works better and faster than the current standard of care in mouse models of TB infection.

14 Dec 2004

Study sheds light on how bacteria persist despite antibiotics

Researchers at the Hebrew University of Jerusalem and Rockefeller University in New York have demonstrated the constant presence of antibiotic-tolerant "persistent cells" within bacteria colonies and have shown, through mathematical modeling, how these cells develop into "normal" cells following their survival of even heavy dosages of antibiotics.

13 Dec 2004

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

An international consortium of scientists lead by Dr. James Paulson of The Scripps Research Institute has created a technology that will advance our understanding of the role of complex sugar chains (glycans or carbohydrates) that decorate the surface of cells in the body.

8 Dec 2004

Dane County patient dumping case unloads costs on consumers

The Wisconsin Hospital Association expressed disappointment with the Wisconsin Supreme Court’s decision yesterday that allows Dane County and other counties to impose yet another hidden tax on health care consumers.

8 Dec 2004

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

"All cancers are marked by some form of DNA replication gone awry, so a basic understanding of DNA replication is of paramount importance to those designing cancer-fighting drugs,"

8 Dec 2004

New clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans

Researchers have unlocked new clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans. One of the keys to this species of bacteria is its production of streptokinase (SK), an enzyme that activates plasminogen, the blood clot-dissolving protein in humans.

6 Dec 2004

New research aims to reduce deaths and ease burden on hospitals

New research by scientists at Australia's Macquarie University will investigate antibiotic resistance genes in humans in an effort to combat worldwide death rates due to infectious diseases and reduce the growing burden on our health system by decreasing patients' length of stay.

6 Dec 2004

Autophagy is also cell's second line of defense against invading pathogens such as strep

Cells give up their secrets slowly. Just when you think that all major cellular systems are understood, along comes a surprise. The latest is about autophagy, a major pathway for degrading and recycling within cells.

4 Dec 2004

New and revealing portrait of Yersinia pestis emerges

Yersinia pestis, the causative agent of the “Black Death” or “Bubonic” plague, has been a scourge of human civilization. One of the most virulent bacterial pathogens known, killing nearly 90% of those infected, Y. pestis was responsible for three historic pandemics that shattered whole societies.

4 Dec 2004

People could be exposed to antibiotic-resistant bacteria from breathing air from swine feeding facilities

People could be exposed to antibiotic-resistant bacteria from breathing the air from concentrated swine feeding facilities, according to researchers at the Johns Hopkins Bloomberg School of Public Health.

4 Dec 2004

FDA approval of cream to treat bacterial vaginosis

KV Pharmaceutical Company has announced that it has received approval from the United States Food and Drug Administration (FDA) to market Clindesse (clindamycin phosphate) Vaginal Cream, 2%, a single-dose prescription cream therapy indicated to treat bacterial vaginosis ("BV").

3 Dec 2004

Oral administration of saline spray may stop spread of influenza, tuberculosis, and SARS

Some individuals exhale many more pathogen-laden droplets than others in the course of ordinary breathing, scientists have found, but oral administration of a safe saline spray every six hours might slash exhalation of germs in this group by an average 72 percent.

29 Nov 2004

Bacterial News and Research

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

Evidence suggests that changes in the bacteria and fungi in the gastrointestinal tract can intensify the immune system's reaction to common allergens

Jumping genes help explain immune system's remarkable ability

Study finds new method can improve chemo survival

Study on first new potential drug for tuberculosis in 40 years

Scientists have identified a novel anti-tuberculosis (TB) compound

Study sheds light on how bacteria persist despite antibiotics

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

Dane County patient dumping case unloads costs on consumers

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

New clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans

New research aims to reduce deaths and ease burden on hospitals

Autophagy is also cell's second line of defense against invading pathogens such as strep

New and revealing portrait of Yersinia pestis emerges

People could be exposed to antibiotic-resistant bacteria from breathing air from swine feeding facilities

FDA approval of cream to treat bacterial vaginosis

Oral administration of saline spray may stop spread of influenza, tuberculosis, and SARS

Salmonella pathogen uses molecular hydrogen to grow and become virulent

FDA approval of Tysabri, for the treatment of multiple sclerosis

Positive results of study with human lactoferrin

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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