Immune System News and Research

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Scientists unravel mystery of T cell signaling process vital to immune response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained a mystery.

16 May 2017

Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

Analysis of a patient's gut microbiome - the microbial population of the gastrointestinal tract - may be able to predict the likelihood of successful treatment for inflammatory bowel disease with biologic drugs that target immune system activity.

16 May 2017

IBM scientists identify new way to trigger the body's immune response to fight diseases

IBM announced its researchers have identified a new way to trigger the body's immune response by using polymer-coated graphene sheets. The research was recently published in Nature Communications.

16 May 2017

Study provides insights into how HCMV infection causes birth defects

Fresh insights into how a common virus replicates could pave the way for new therapies to stop its spread.

15 May 2017

Scientists discover simple way to use light for steering killer immune cells toward tumors

The science behind harnessing the immune system to fight cancer is complicated, but a University of Rochester Medical Center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumors.

15 May 2017

Scientists uncover potential strategy to shock and kill HIV virus

Scientists at the Gladstone Institutes discovered that an enzyme called SMYD2 could be a new therapeutic target for flushing out the HIV that hides in infected individuals. Overcoming this latent virus remains the most significant obstacle to a cure.

15 May 2017

New research could lead to earlier diagnosis and better management of inflammatory bowel disease

A University of Manchester test on the mucus lining of the intestine, performed in mice, has found changes in bacteria that could lead to inflammatory bowel disease 12 weeks earlier than previously possible through looking at stool samples, leading to the possibility of earlier diagnosis and better management of the disease in humans.

From The University of Manchester 15 May 2017

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

ImmusanT, Inc., a clinical-stage company developing Nexvax2, a therapeutic vaccine intended to protect against the effects of gluten exposure while maintaining a gluten-free diet in HLA-DQ2.5+ patients with celiac disease, today announced the publication of positive data from two Phase 1 clinical trials of Nexvax2 in celiac disease.

12 May 2017

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

In the body, anti-cancer immunity is immobilized by stealth cancer forces. But a natural de-immobilizer has been identified - and it has a vendetta.

12 May 2017

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

Boosting a part of the immune system known to have anti-tumor properties may actually help tumors grow in cancers linked to chronic inflammation.

12 May 2017

Scientists reveal how immune cells activate to kill parasitic worms

An international team of researchers including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine, reveals how immune cells called macrophages activate to kill parasitic worms.

11 May 2017

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet in Munich led by Professor Heiko Hermeking have now uncovered the molecular mechanism that links the two phenomena.

11 May 2017

Introduction of ART has increased life expectancy in HIV patients by 10 years

A study published in the journal The Lancet HIV has found an increase in life expectancy of 20-year-old HIV patients in the EU and North America who had started antiretroviral therapy (ART) after it was introduced mid-1990s. When compared with patients who were not treated with ART, the life expectancy had increased by around a decade in these patients.

11 May 2017

Study generates comprehensive catalog of diseases linked to variations in HLA genes

A study led by researchers at Vanderbilt University Medical Center and the University of Arizona College of Pharmacy has generated the first comprehensive catalog of diseases associated with variations in human leukocyte antigen genes that regulate the body's immune system.

11 May 2017

Immune System News and Research

Scientists unravel mystery of T cell signaling process vital to immune response

Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

IBM scientists identify new way to trigger the body's immune response to fight diseases

Study provides insights into how HCMV infection causes birth defects

Scientists discover simple way to use light for steering killer immune cells toward tumors

Scientists uncover potential strategy to shock and kill HIV virus

New research could lead to earlier diagnosis and better management of inflammatory bowel disease

Phase 1 clinical studies reveal safety, tolerability of therapeutic vaccine in celiac disease patients

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

Scientists reveal how immune cells activate to kill parasitic worms

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

Introduction of ART has increased life expectancy in HIV patients by 10 years

Study generates comprehensive catalog of diseases linked to variations in HLA genes

Researchers identify cells that drive autoimmune disease

Researchers uncover structure of embryo-protecting protein

Mothers infected with malaria during pregnancy can alter infants’ immunity

New method helps visualize, measure real-time lipid metabolism in living fish

Study: Brain injury can increase impulsivity problems in rats

Breast-feeding transfers beneficial bacteria to the baby’s gut, new study finds

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