Immune System News and Research

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CRISPR technology shows potential as a “molecular recorder” through DNA encoded movie

The researchers from Harvard University, Seth L. Shipman, Jeff Nivala, Jeffrey D. Macklis and George M. Church, believe that their study is a major step forward to a "molecular recorder" that may someday make it possible to get read-outs, has published online their proof-of-concept on July 12, 2017, in the journal Nature.

14 Jul 2017

FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

A Food and Drug Administration (FDA) panel created history by recommending a gene therapy for patients with cancer. In this therapy the patient’s own genes would be modified to fight the cancer cells. The patient’s cells which are thus altered to treat the cancer would thus be termed as “living drugs” as they act as soldiers to treat the cancer. These cells boost up the immune system and help the body fight the cancer.

14 Jul 2017

Scientists positively influence immune response in viral and bacterial co-infection

Researchers from Charité - Universitätsmedizin Berlin were able to positively influence the immune response in severe viral and bacterial co-infection.

13 Jul 2017

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia.

13 Jul 2017

FDA advisory committee recommends Novartis' CAR-T therapy for young leukemia patients

Today the FDA's Oncologic Drugs Advisory Committee, an independent panel of experts, voted unanimously to recommend to the FDA approval of Novartis' experimental CAR-T therapy called Tisagenlecleucel, also known as CTL019.

13 Jul 2017

Nagoya University researchers define new category of genetic skin diseases

Nagoya University-led team reviews skin diseases to define a new type of genetic-based inflammation for improving diagnosis and treatment of rare skin conditions.

13 Jul 2017

Targeting acid metabolite reduces size and spread of breast cancer

It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability to spread to the lungs.

12 Jul 2017

Researchers unlock better treatment strategy for viral diseases

RMIT University scientists in Melbourne, Australia, have led an international collaboration that potentially unlocks better treatment of viral diseases, including the flu and common cold.

12 Jul 2017

Ocular microbiome trains developing immune system to ward off pathogens, study shows

Bugs in your eyes may be a good thing. Resident microbes living on the eye are essential for immune responses that protect the eye from infection, new research shows.

11 Jul 2017

Antibiotic use during peripartum period linked to greater risk of inflammatory condition in offspring

A study by researchers at the University of Chicago Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles human IBD.

11 Jul 2017

Women and men with bipolar disorder may have different immune markers

Men and women react differently to compounds associated with immune system response to bipolar disorder, according to Penn State College of Medicine researchers.

11 Jul 2017

Intestinal viruses may affect person's chance of developing Type 1 diabetes

Doctors can't predict who will develop Type 1 diabetes, a chronic autoimmune disease in which one's own immune system destroys the cells needed to control blood-sugar levels, requiring daily insulin injections and continual monitoring.

11 Jul 2017

Ubiquitous human herpesvirus 6 may play key role in brain diseases like multiple sclerosis

The ubiquitous human herpesvirus 6 (HHV-6) may play a critical role in impeding the brain's ability to repair itself in diseases like multiple sclerosis.

10 Jul 2017

JAX researchers explore how dendritic cells promote adaptive immunity to virus

A research team led by Jackson Laboratory Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a long-standing puzzle of immunology: How do dendritic cells (DCs) do their job of promoting adaptive immunity to a virus while avoiding getting infected themselves?

7 Jul 2017

Researchers receive $8.6 million NIH grant for efforts to improve lung transplantation

Researchers at the University of Virginia School of Medicine have received more than $8.6 million in federal grants to support efforts that could dramatically increase the number of lungs available for transplant – and then save the lives of the people who receive them.

6 Jul 2017

Zirconia-doped ceria nanoparticles can act as effective antioxidants in sepsis treatment

During sepsis, cells are swamped with reactive oxygen species generated in an aberrant response of the immune system to a local infection.

6 Jul 2017

Marine natural compounds hold potential to combat tuberculosis

A team of researchers at the University of Central Florida has discovered a potential new weapon in the fight against tuberculosis, and it lives in the Little Mermaid's realm.

6 Jul 2017

Sialic acid found in animals protects farm children from asthma

It is a known fact that microbes on farms protect children from asthma and allergies. But even non-microbial molecules can have a protective effect: Immunologists from the University of Zurich have shown that a sialic acid found in farm animals is effective against inflammation of lung tissue.

6 Jul 2017

Scientists develop novel DNA-based strategy to protect against broad array of influenza viruses

A novel, synthetic, DNA-based strategy to provide protection against a broad array of influenza viruses has been developed in preclinical models by scientists at The Wistar Institute, MedImmune (the global biologics research and development arm of AstraZeneca) and Inovio Pharmaceuticals, Inc.

6 Jul 2017

Combination therapy may lead to new standard of care for kidney cancer patients

Combination therapy with two immunotherapy drugs produces an unprecedented doubling of response rates from 20 percent to 40 percent, new study shows.

6 Jul 2017

Immune System News and Research

CRISPR technology shows potential as a “molecular recorder” through DNA encoded movie

FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

Scientists positively influence immune response in viral and bacterial co-infection

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

FDA advisory committee recommends Novartis' CAR-T therapy for young leukemia patients

Nagoya University researchers define new category of genetic skin diseases

Targeting acid metabolite reduces size and spread of breast cancer

Researchers unlock better treatment strategy for viral diseases

Ocular microbiome trains developing immune system to ward off pathogens, study shows

Antibiotic use during peripartum period linked to greater risk of inflammatory condition in offspring

Women and men with bipolar disorder may have different immune markers

Intestinal viruses may affect person's chance of developing Type 1 diabetes

Ubiquitous human herpesvirus 6 may play key role in brain diseases like multiple sclerosis

JAX researchers explore how dendritic cells promote adaptive immunity to virus

Researchers receive $8.6 million NIH grant for efforts to improve lung transplantation

Zirconia-doped ceria nanoparticles can act as effective antioxidants in sepsis treatment

Marine natural compounds hold potential to combat tuberculosis

Sialic acid found in animals protects farm children from asthma

Scientists develop novel DNA-based strategy to protect against broad array of influenza viruses

Combination therapy may lead to new standard of care for kidney cancer patients

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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