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NYSCF announce partnership with Ngene to develop new disease treatments

The New York Stem Cell Foundation Research Institute today announced a partnership with Ngene Therapeutics Inc. to develop new disease treatments that leverage human stem cell research and novel gene editing techniques.

10 Jan 2019

Microbial metabolite from pomegranates can reduce and protect against IBD

Scientists at the University of Louisville have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, can reduce and protect against inflammatory bowel disease.

10 Jan 2019

Mechanism underlying impaired allergic inflammation in children may explain hygiene hypothesis

The hygiene hypothesis may explain why asthma and other allergic airway diseases have dramatically increased over the past decades in industrialized countries.

9 Jan 2019

Investigational topical cream may be effective for treating atopic dermatitis

A study published in the British Journal of Dermatology indicates that an investigational nonsteroidal topical cream may be effective for treating atopic dermatitis, one of the most common inflammatory skin diseases.

9 Jan 2019

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Millions of people suffer from inflammatory bowel disease worldwide, either in the form of ulcerative colitis or Crohn's disease, and few effective long-term treatments are available. Chronic intestinal inflammation is a hallmark of IBD.

9 Jan 2019

New mechanism of gene regulation involved in tumor progression discovered

Genes contain all the information needed for the functioning of cells, tissues, and organs in our body. Gene expression, meaning when and how are the genes being read and executed, is thoroughly regulated like an assembly line with several things happening one after another.

9 Jan 2019

Study: Rutin found in fruits and vegetables protect mice against snake venom

Rutin, a bioflavonoid found in certain vegetables and fruits, protects mice against snake venom by minimizing bleeding and inflammation, according to a study performed at the Butantan Institute, a research institution belonging to the government of São Paulo State in Brazil.

9 Jan 2019

FDA approves initiation of first-in-human trial of DNA-encoded monoclonal antibody

The Wistar Institute, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc., announce that the FDA has approved the initiation of a first-in-human clinical trial investigating the safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody therapeutic technology for the prevention of Zika virus infection.

9 Jan 2019

Essential nutrient may hold promise in the war against Alzheimer's disease

In a new study, researchers at the Biodesign Institute explore a safe and simple treatment for one of the most devastating and perplexing afflictions: Alzheimer's disease.

8 Jan 2019

High-fat diets shown to increase blood pressure

A new study has added to the evidence that a high-fat diet is unhealthy for both younger males and females. The study also found sex-linked differences in the physiological effects of a HFD.

8 Jan 2019

Higher fat consumption appear to be bad for blood pressure in younger males and females

There's more evidence that a high-fat diet is bad for both younger males and females, but exactly how it's harmful may differ between the sexes, scientists report.

8 Jan 2019

CytoReason enters into drug discovery collaboration agreement with Pfizer

CytoReason, a leader in machine learning for drug discovery and development, announced today that it has entered into a collaboration agreement with Pfizer Inc. that will leverage CytoReason's cell-centered models of the immune system.

8 Jan 2019

Washington University scientists find an unknown route for cellular fuel delivery

Scientists at Washington University School of Medicine in St. Louis have identified a previously unknown route for cellular fuel delivery, a finding that could shed light on the process of aging and the chronic diseases that often accompany it.

8 Jan 2019

MGH-led research team reveals how solid stress impacts tissue surrounding brain tumors

A Massachusetts General Hospital-led research team has demonstrated, for the first time, how solid stress - the physical forces exerted by the solid components of a tumor - impacts the tissue surrounding brain tumors and contributes to resulting neurological dysfunction and neuronal cell death.

8 Jan 2019

Study of rare uterine sarcoma reveals clinically relevant molecular subtypes

Undifferentiated uterine sarcoma is a very rare but extremely aggressive cancer type. It can be divided into four groups with different characteristics of clinical importance - a new study at Karolinska Institutet reveals.

7 Jan 2019

Faulty immune receptor in HIV patients could be reason why many experience complications

For HIV patients, treatments that control the infection have come a long way. But many still struggle with a host of other disease-related complications such as neurocognitive disorders, cardiovascular issues, diabetes and chronic inflammation.

7 Jan 2019

First viable mouse model of Hirschsprung's disease developed

About one in every 5,000 babies is born without enteric neurons in distal colon resulting in Hirschsprung's disease. Because of the lacking neurons, contents of the gut cannot pass normally resulting in constipation and enlargement of colon.

7 Jan 2019

Higher vitamin C intake crucial for metabolic syndrome patients to halt cycle of antioxidant disruption

A higher intake of vitamin C is crucial for metabolic syndrome patients trying to halt a potentially deadly cycle of antioxidant disruption and health-related problems, an Oregon State University researcher says.

2 Jan 2019

New research could help restore youthful characteristics

If only we could keep our bodies young, healthy and energetic, even as we attain the wisdom of our years. New research at the Weizmann Institute of Science suggests this dream could be at least partly obtainable in the future.

2 Jan 2019

New insights on cellular death mechanisms caused by the loss of neuronal cells and astrocytes

The blood circulation to neurons is affected due to Ischemic, hemorrhagic stroke and subarachnoid hemorrhage stimulation the activation of pathophysiological responses i.e. mitochondrial death pathways, protein misfolding, apoptosis, pyroptosis, necrosis, autophagy, mitophagy, ferritinophagy, excitotoxicity, free radicals release, and inflammation.

31 Dec 2018

Inflammation News and Research

NYSCF announce partnership with Ngene to develop new disease treatments

Microbial metabolite from pomegranates can reduce and protect against IBD

Mechanism underlying impaired allergic inflammation in children may explain hygiene hypothesis

Investigational topical cream may be effective for treating atopic dermatitis

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

New mechanism of gene regulation involved in tumor progression discovered

Study: Rutin found in fruits and vegetables protect mice against snake venom

FDA approves initiation of first-in-human trial of DNA-encoded monoclonal antibody

Essential nutrient may hold promise in the war against Alzheimer's disease

High-fat diets shown to increase blood pressure

Higher fat consumption appear to be bad for blood pressure in younger males and females

CytoReason enters into drug discovery collaboration agreement with Pfizer

Washington University scientists find an unknown route for cellular fuel delivery

MGH-led research team reveals how solid stress impacts tissue surrounding brain tumors

Study of rare uterine sarcoma reveals clinically relevant molecular subtypes

Faulty immune receptor in HIV patients could be reason why many experience complications

First viable mouse model of Hirschsprung's disease developed

Higher vitamin C intake crucial for metabolic syndrome patients to halt cycle of antioxidant disruption

New research could help restore youthful characteristics

New insights on cellular death mechanisms caused by the loss of neuronal cells and astrocytes

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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