Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

BUSM, BMC anesthesiologists win APSF's Ellison C. Pierce Award

For the second consecutive year, anesthesiologists from Boston Medical Center (BMC) and Boston University School of Medicine (BUSM) have received the prestigious Ellison C. Pierce Award for the Best Scientific Exhibit in Patient Safety from the Anesthesia Patient Safety Foundation.

1 Dec 2011

New insights into immune-system changes that may trigger cartilage breakdown

Challenging long-held notions that osteoarthritis is a result mainly of wear and tear on the joints, researchers led by Dr. William H. Robinson of the Department of Veterans Affairs Palo Alto Health Care System and Stanford University have provided new insights into the immune-system changes that may trigger cartilage breakdown.

21 Nov 2011

Stem cell bandage human clinical trial for torn meniscal cartilage

The company behind a pioneering stem cell bandage, believed to be the world's first adult and autologous (patient's own) stem cell treatment designed to heal torn meniscal cartilage, can now take the technology to human clinical trials thanks to an investment from one of the UK's most successful entrepreneurs.

14 Nov 2011

Special supplement examines effects of articular cartilage injury, degeneration in soccer players

More than 300 million play soccer across the globe and while the game is one of fast footwork, two organizations are trying to make sure these athletes stay on their feet. F-d-ration Internationale de Football Association (FIFA) and International Cartilage Repair Society (ICRS) have teamed up on a special supplement of Cartilage (published by SAGE) that examines the effects of articular cartilage injury and degeneration in soccer players.

14 Nov 2011

Cultivating cells in sealed, sterile plastic bags

Using plasmas, sealed plastic bags can be modified at atmospheric pressure so that human cells can adhere to and reproduce on their walls. Cell culture bags of this kind are an important aid for research and clinical purposes and may eventually replace the Petri dishes used today.

11 Nov 2011

New genetic approach to treat fibrodysplasia ossificans progressiva

Scientists at Penn's Perelman School of Medicine Center for Research in FOP and Related Disorders have developed a new genetic approach to specifically block the damaged copy of the gene for a rare bone disease, while leaving the normal copy untouched.

9 Nov 2011

BioMimetic Therapeutics reports third quarter total revenues of $0.4M

BioMimetic Therapeutics, Inc., a biotechnology company specializing in the development and commercialization of innovative bioactive products to promote the healing of musculoskeletal injuries and diseases, today reported its financial results as of and for the three and nine months ended September 30, 2011.

9 Nov 2011

Infinity third quarter total revenue increases marginally to $23.3 million

Infinity Pharmaceuticals, Inc. today highlighted its recent clinical and business progress and announced its third quarter 2011 financial results.

9 Nov 2011

ACR honors NYU Langone professor with Distinguished Basic Investigator Award

Steven B. Abramson, MD, senior vice president and vice dean of education, faculty and academic affairs and professor, Departments of Medicine and Pathology at NYU Langone Medical Center received the Distinguished Basic Investigator Award at the American College of Rheumatology (ACR) & Association of Rheumatology Health Professionals (ARHP) annual scientific meeting this week in Chicago.

8 Nov 2011

Low-grade inflammatory processes drive development of osteoarthritis

In a study to be published online Nov. 6 in Nature Medicine, investigators at the Stanford University School of Medicine have shown that the development of osteoarthritis is in great part driven by low-grade inflammatory processes.

8 Nov 2011

$Narcotic analgesics increase risk of falls and fractures among elderly$

Narcotic analgesics increase risk of falls and fractures among elderly

Falls and fractures among senior citizens have increased since rofecoxib was removed from the market in 2004, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago.

7 Nov 2011

Sports participation may increase risk of knee osteoarthritis

According to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago, participating in certain sports such as soccer, as well as elite long distance running, weight lighting and wrestling may increase the risk of developing knee osteoarthritis.

7 Nov 2011

Nearly 6.5M younger Americans to be diagnosed with knee OA in next ten years

Based on current trends, nearly 6.5 million Americans between the ages of 35 and 84 are expected to be diagnosed with knee osteoarthritis in the next 10 years, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago.

7 Nov 2011

Intensive diet, exercise reduce pain and improve mobility in people with knee OA

According to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago, weight loss combined with exercise reduces pain and improves mobility in people with knee osteoarthritis.

7 Nov 2011

$Postmenopausal women with OA have higher risk of bone fractures, falls$

Postmenopausal women with OA have higher risk of bone fractures, falls

Postmenopausal women with osteoarthritis have a 20 percent higher risk of bone fractures and experience almost 30 percent more falls than those without the disease, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago.

7 Nov 2011

Final results from Vertex VX-509 Phase 2a study on RA

Vertex Pharmaceuticals Incorporated today announced the final results from a Phase 2a study of the investigational selective oral JAK3 inhibitor VX-509.

6 Nov 2011

Rothman researchers to develop gold standard definition for periprosthetic joint infection

A rise in periprosthetic joint infection (PJI) rates has the orthopedic community moving to develop it's first-ever agreed upon definition and diagnostic criteria to help better treat patients.

5 Nov 2011

MSCs can be reprogrammed to have enhanced survival and therapeutic efficacy

Chinese stem cell scientists have published new research that improves the survival and effectiveness of transplanted stem cells. The research led by Dr Hsiao Chang Chan, from the Chinese University of Hong Kong, is published in Stem Cells.

3 Nov 2011

Biogen Idec enters global collaboration for oral Syk inhibitor program with Portola

Biogen Idec and Portola Pharmaceuticals, Inc. today announced that they have entered into an exclusive, worldwide collaboration and license agreement under which both companies will develop and commercialize highly selective, novel oral Syk inhibitors for the treatment of various autoimmune and inflammatory diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).

28 Oct 2011

Regeneron announces positive results from sarilumab Phase 2b trial on RA

Regeneron Pharmaceuticals, Inc. today announced that detailed clinical data from the positive Phase 2b portion of the seamless Phase 2/3 MOBILITY trial of sarilumab in rheumatoid arthritis (RA) will be presented at a late-breaking poster session at the upcoming American College of Rheumatology (ACR) Annual Scientific Meeting, which will take place from November 5-9 in Chicago.

28 Oct 2011