Immunoglobulin News and Research

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Low neutralizing antibody titers against SARS-CoV-2 Mu in BNT162b2 vaccinated

Researchers assess the neutralizing antibody titers in BNT162b2-vaccinated people against SARS-CoV-2 isolates from the Mu, Gamma, and B.1.111 lineages.

28 Nov 2021

A review of natural immunity, vaccines, and variants in SARS-CoV-2 reinfection

In a literature review article published in the Journal of Community Hospital Internal Medicine Perspectives, authors from the US performed a thorough investigation of previous studies and case reports of SARS-CoV-2 reinfection. This review discusses the role of natural immunity, vaccines, and SARS-CoV-2 variants in reinfection.

25 Nov 2021

Study explores adverse effects of SARS-CoV-2-induced antibody responses

The authors of a research paper published in the journal Frontiers in Immunology used Sandwich ELISA tests to determine the distribution of IgG sub-classes and complement activation levels in plasma from convalescent individuals.

25 Nov 2021

COVID-19 vaccine boosters to prevent breakthrough SARS-CoV-2 infections in healthy adults

Researchers measured anti-RBD IgG and virus neutralization before and after vaccination with boosters.

25 Nov 2021

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Researchers conducted a study on COVID-19 convalescent patients and post-vaccinated populations to identify the minimal levels of antibody required to protect against SARS-CoV-2 infection.

24 Nov 2021

Limited immune responses three months after Pfizer-BioNTech vaccination among elderly

In this study, published on the medRxiv* preprint server, the humoral response to SARS-CoV-2 was assessed before and after three months of administration of the BNT162b2 mRNA COVID-19 vaccination (Pfizer-BioNTech). In addition, elders' humoral responses were compared to those of a younger group, and a functional neutralization experiment against the Wuhan-Hu-1 (WH1) virus and the Delta variant was carried out.

23 Nov 2021

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Scientists generate a VLP type NP platform made of recombinant viral antigens conjugated with TMV virions.

23 Nov 2021

Inactivated virion-based vaccine confers robust cell-mediated immunity against major SARS-CoV-2 variants

Indian researchers determine the magnitude, quality, and persistence of cellular and humoral memory responses after vaccination with BBV152/Covaxin.

23 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

REGEN-COV is effective in preventing severe COVID-19 in immunocompromised individuals

A recent study assesses the efficacy of repeat doses of REGEN-COV in SARS-CoV-2-negative adults who were healthy or had chronic medical conditions.

18 Nov 2021

NIH study finds naturally acquired immunity is weak against SARS-CoV-2 variants

Immunity acquired after recovering from SARS-CoV-2 infection is not sufficient in protecting against reinfection from variants.

18 Nov 2021

Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern

Canadian public health researchers recently published a study in the journal Antiviral Research wherein they described generating a panel of murine hybridomas recognizing SARS-CoV-2 spike protein or nucleoprotein, capable of neutralizing the SARS-CoV-2 variants of concern, proving their therapeutic potential.

17 Nov 2021

Long-term Pfizer vaccine-elicited SARS-CoV-2 antibody profile in breast milk

A new study indicates that the Pfizer vaccine induces antibodies in the breast milk against SARS-CoV-2.

17 Nov 2021

SARS-CoV-2 reinfection associated with housing instability

Researchers examine the impact of demographic factors and antibody responses following SARS-CoV-2 reinfection.

17 Nov 2021

Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

A new study published in the journal Diagnostics was based on the hypothesis that detecting urinary SARS-CoV-2 nucleic acid––which may result in renal and cardiovascular endothelial destruction to facilitate viral access to the kidney parenchyma—may be used as a specific biomarker to indicate the severity of COVID-19.

16 Nov 2021

Immunoglobulin News and Research

Low neutralizing antibody titers against SARS-CoV-2 Mu in BNT162b2 vaccinated

A review of natural immunity, vaccines, and variants in SARS-CoV-2 reinfection

Study explores adverse effects of SARS-CoV-2-induced antibody responses

COVID-19 vaccine boosters to prevent breakthrough SARS-CoV-2 infections in healthy adults

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Limited immune responses three months after Pfizer-BioNTech vaccination among elderly

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Inactivated virion-based vaccine confers robust cell-mediated immunity against major SARS-CoV-2 variants

Paper-based innovations for COVID-19 diagnosis

REGEN-COV is effective in preventing severe COVID-19 in immunocompromised individuals

NIH study finds naturally acquired immunity is weak against SARS-CoV-2 variants

Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern

Long-term Pfizer vaccine-elicited SARS-CoV-2 antibody profile in breast milk

SARS-CoV-2 reinfection associated with housing instability

Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

Rapid finger stick test to detect antibodies against SARS-CoV-2 variants

Thrombosis with thrombocytopenia syndrome rare but serious adverse event associated with Ad26.COV2.S vaccination

Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases

The case for vaccinating children under 12 against COVID-19

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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