Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Analysis: Keto diets place pregnant women and kidney disease patients at risk of adverse health effects

In the most comprehensive analysis yet of ketogenic (keto) diets, a review in Frontiers in Nutrition finds keto diets place pregnant women and kidney disease patients at risk of adverse health effects.

3 Aug 2021

Two new proteins identified as therapeutic targets for preventing NAFLD and associated liver cancer

An international study led by the Lipids&Liver research team at the UPV/EHU-University of the Basque Country, the results of which have recently been published in the prestigious journal Cancer Research, has demonstrated that inhibiting either of the proteins E2F1 or E2F2 in the liver protects against the development of obesity-driven nonalcoholic fatty liver disease and its progression to cancer.

29 Jul 2021

3D imaging reveals degeneration of liver sympathetic nerves in nonalcoholic fatty liver disease

With the application of a novel three-dimensional imaging technology, researchers at Karolinska Institutet in Sweden have discovered that one portion of the autonomic nervous system in the liver undergoes severe degeneration in non-alcoholic fatty liver disease.

22 Jul 2021

'Good cholesterol' protects the liver from inflammation and injury, study shows

The body's so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury.

22 Jul 2021

Children of obese mothers at increased risk of fatty liver disease

Children and young people whose mothers had a BMI greater than 30 during early pregnancy are at an increased risk of fatty liver disease.

19 Jul 2021

Chemical modification in RNA molecules may offer protection against liver disease

A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells' protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver and can lead to advanced liver disease, according to a new study by UCLA researchers.

19 Jul 2021

New study finds an association between alcohol use and higher risk of several cancers

A new study from the World Health Organization's International Agency for Research on Cancer (IARC), published in the journal Lancet Oncology, has found an association between alcohol and a substantially higher risk of several forms of cancer, including breast, colon, and oral cancers.

14 Jul 2021

Study reveals how non-alcoholic fatty liver disease can develop into a life-threatening complication

Researchers revealed how non-alcoholic fatty liver disease can develop into a life-threatening complication.

13 Jul 2021

Patient characteristics including demographic factors and comorbidities can accurately predict the outcome of COVID-19 infection severity

New machine learning models incorporating COVID-19 infection data show that patient demography is a key predictor of infection outcome.

13 Jul 2021

Selective immunotoxins may help treat liver fibrosis

Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

12 Jul 2021

New approach that uses machine learning could transform drug development

Writing in the July 12, 2021 online issue of Nature Communications, researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

12 Jul 2021

Adults with ADHD at higher risk of many physical conditions, finds study

Adults with ADHD are at higher risk of a wide range of physical conditions, including nervous system, respiratory, musculoskeletal, and metabolic diseases, according to a large register-based study from Karolinska Institutet in Sweden published in The Lancet Psychiatry.

7 Jul 2021

22 blood plasma lipids found to be associated with lower symptom improvement in schizophrenia

Researchers from Skoltech and the Mental Health Research Center have found 22 lipids in the blood plasma of people with schizophrenia that were associated with lower symptom improvement over time during treatment.

6 Jul 2021

A new method for generating metabolic profiles of single cells

Scientists from the European Molecular Biology Laboratory and the German Cancer Research Center have presented a new method for generating metabolic profiles of individual cells.

6 Jul 2021

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice.

6 Jul 2021

Scientists outline new target for treating type 2 diabetes

This year marks the 100th anniversary of the discovery of insulin, a scientific breakthrough that transformed Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, from a terminal disease into a manageable condition.

30 Jun 2021

CN Bio’s PhysioMimix™ adopted by King’s College London to investigate chronic liver disease

CN Bio today announced that King’s College London, an internationally renowned research university, has adopted the PhysioMimix™ Multi-Organ MPS.

From CN Bio 29 Jun 2021

Researcher receives $2.5 million award to curb HIV infection among people who inject drugs

International organizations and countries around the world are working to eliminate HIV/AIDS by 2030. To reach this goal, new approaches are needed--particularly among difficult-to-reach groups such as people who inject drugs (PWID), who are 30 times more likely to contract HIV/AIDS compared with the general population.

28 Jun 2021

Preliminary results of AAV-mediated gene therapy for Crigler Najjar syndrome

Preliminary results from the European gene therapy trial for Crigler-Najjar syndrome, conducted by Genethon in collaboration with European network CureCN, were presented at the EASL (European Association for the Study of the Liver) annual International Liver Congress on June 26.

28 Jun 2021

Study examines effect of sorafenib in patients with advanced hepatocellular carcinoma

Oncotarget published "Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib" which reported that this study investigated the association of the IGF/CTP score with overall survival and progression-free survival of HCC patients treated with sorafenib.

28 Jun 2021

Liver Disease News and Research

Further Reading

Analysis: Keto diets place pregnant women and kidney disease patients at risk of adverse health effects

Two new proteins identified as therapeutic targets for preventing NAFLD and associated liver cancer

3D imaging reveals degeneration of liver sympathetic nerves in nonalcoholic fatty liver disease

'Good cholesterol' protects the liver from inflammation and injury, study shows

Children of obese mothers at increased risk of fatty liver disease

Chemical modification in RNA molecules may offer protection against liver disease

New study finds an association between alcohol use and higher risk of several cancers

Study reveals how non-alcoholic fatty liver disease can develop into a life-threatening complication

Patient characteristics including demographic factors and comorbidities can accurately predict the outcome of COVID-19 infection severity

Selective immunotoxins may help treat liver fibrosis

New approach that uses machine learning could transform drug development

Adults with ADHD at higher risk of many physical conditions, finds study

22 blood plasma lipids found to be associated with lower symptom improvement in schizophrenia

A new method for generating metabolic profiles of single cells

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Scientists outline new target for treating type 2 diabetes

CN Bio’s PhysioMimix™ adopted by King’s College London to investigate chronic liver disease

Researcher receives $2.5 million award to curb HIV infection among people who inject drugs

Preliminary results of AAV-mediated gene therapy for Crigler Najjar syndrome

Study examines effect of sorafenib in patients with advanced hepatocellular carcinoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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