Malignant News and Research

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Scientists discover mechanism by which epithelial tumors cause maturation defects

Conducted on the fly Drosophila, the study shows that tumors caused by chromosomal instability delay entry into the adult phase.

23 Feb 2021

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma

Cancer cells acquire growth advantages over normal cells in myriad ways. Changes in cell programming allow these cells to grow in an uncontrolled fashion, thereby forming the cancer mass.

23 Feb 2021

3D microscopy analysis provides accurate recreation of human glioblastoma’s features

Researchers at the Institut de Neurociències obtained a highly accurate recreation of human glioblastoma’s features using a novel 3D microscopy analysis

19 Feb 2021

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

The first randomized Phase II clinical trial to report on single and combined neoadjuvant immune checkpoint inhibitor therapy in stage I-III non-small cell lung cancer (NSCLC) found combination therapy produced a significant clinical benefit, as assessed by major pathologic response (MPR) rate, as well as enhanced tumor immune cell infiltration and immunological memory.

18 Feb 2021

Study reveals extremely low detection of SARS-CoV-2 on surfaces in oncology facilities

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, evaluated the frequency of SARS-CoV-2, the virus that causes COVID-19, on various environmental surfaces in outpatient and inpatient hematology/oncology settings located within Rutgers Cancer Institute and Robert Wood Johnson University Hospital, an RWJBarnabas Health facility.

18 Feb 2021

Researchers evaluate frequency of SARS-CoV-2 in hematology/oncology settings

18 Feb 2021

Accumulation of fatty tissue in the neck predicts adiposity, heart problems

Researchers from the University of Granada warn that an accumulation of fatty tissue in the neck (both the double chin and the deeper deposits, located between muscles and around the cervical vertebrae) is a predictor of central and overall adiposity, cardiometabolic risk, and a pro-inflammatory profile in sedentary young adults.

17 Feb 2021

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

The National Cancer Institute has granted a $2.5 million, five-year R37 MERIT Award to Dr. Bryan Burt, associate professor of surgery and chief of the Division of General Thoracic Surgery, for his research project titled, "Proteomic Determinants of Response to Checkpoint Blockade in Malignant Pleural Mesothelioma."

16 Feb 2021

Scientists discover new immunotherapy target for malignant brain tumors

Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system.

15 Feb 2021

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

Today, the U.S. Food and Drug Administration approved Cosela (trilaciclib) as the first therapy in its class to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage (when the cancer has spread beyond the lungs) small cell lung cancer.

13 Feb 2021

Disrupting cancer cell cycle with two commercially available inhibitors causes tumor cell death

With two commercially available inhibitors, the cell cycle of the cancer cells in the childhood tumor neuroblastoma can be disrupted at a key point causing tumor cell death.

12 Feb 2021

New review summarises effect of aquatic pollution on cancer prevalence in wild animals

The recent review, published in Environment International and led by the University of Tartu, summarises the effect of aquatic pollution on cancer prevalence in wild animals with the help of more than 300 reviewed studies.

11 Feb 2021

Inherited genetic variation may affect the response to cancer immunotherapy

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer.

10 Feb 2021

Gene panel test enables highly accurate diagnosis of liposarcomas

Researchers have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel test that allows for highly accurate diagnosis of the most common types of liposarcoma.

5 Feb 2021

Novel 3D-printed esophageal stents could revolutionize the delivery of cancer treatment

World-first 3D printed esophageal stents developed by the University of South Australia could revolutionize the delivery of chemotherapy drugs to provide more accurate, effective and personalized treatment for patients with esophageal cancer.

3 Feb 2021

New technology uses near-infrared imaging and machine learning to find hidden tumors

Tumors can be damaging to surrounding blood vessels and tissues even if they're benign. If they're malignant, they're aggressive and sneaky, and often irrevocably damaging. In the latter case, early detection is key to treatment and recovery.

3 Feb 2021

Nivolumab monotherapy is effective treatment option for relapsed malignant mesothelioma

Nivolumab monotherapy is an effective treatment option for relapsed malignant mesothelioma (MM), according to research presented today at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.

31 Jan 2021

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts (a type of cells found in connective tissue), namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer.

30 Jan 2021

Physicians receive Pfizer Prize for research on leukemia, cardiac arrhythmias

This year, four of a total of fifteen Pfizer Research Prizes have been awarded to physicians from the University of Bern and the Inselspital, University Hospital Bern.

28 Jan 2021

New results challenge the current understanding of medulloblastoma

Scientists at St. Jude Children's Research Hospital and their colleagues have published a detailed account of SJMB03, a clinical trial for pediatric patients with medulloblastoma.

28 Jan 2021

Malignant News and Research

Scientists discover mechanism by which epithelial tumors cause maturation defects

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma

3D microscopy analysis provides accurate recreation of human glioblastoma’s features

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

Study reveals extremely low detection of SARS-CoV-2 on surfaces in oncology facilities

Researchers evaluate frequency of SARS-CoV-2 in hematology/oncology settings

Accumulation of fatty tissue in the neck predicts adiposity, heart problems

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

Scientists discover new immunotherapy target for malignant brain tumors

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

Disrupting cancer cell cycle with two commercially available inhibitors causes tumor cell death

New review summarises effect of aquatic pollution on cancer prevalence in wild animals

Inherited genetic variation may affect the response to cancer immunotherapy

Gene panel test enables highly accurate diagnosis of liposarcomas

Novel 3D-printed esophageal stents could revolutionize the delivery of cancer treatment

New technology uses near-infrared imaging and machine learning to find hidden tumors

Nivolumab monotherapy is effective treatment option for relapsed malignant mesothelioma

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

Physicians receive Pfizer Prize for research on leukemia, cardiac arrhythmias

New results challenge the current understanding of medulloblastoma

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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