Mitochondria News and Research

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Increasing energy supply within injured spinal cord nerves could help them heal

When the spinal cord is injured, the damaged nerve fibers--called axons--are normally incapable of regrowth, leading to permanent loss of function.

3 Mar 2020

Researchers explore the role of SLC25A32 in cancer cell proliferation

Oncotarget Volume 11 Issue 8 reported that while it is known that cancer cells require one-carbon and FAD-dependent mitochondrial metabolism to sustain cell proliferation, the role of SLC25A32 in cancer cell growth remains unexplored.

28 Feb 2020

Switching what heart cells consume could help them regenerate

Switching what the powerhouses of heart cells consume for energy could help the heart regenerate when cells die, a new study led by UT Southwestern researchers suggests.

23 Feb 2020

Researchers discover glial cells that control stress response, extend lifespan in worms

While many of us worry about proteins aggregating in our brains as we age and potentially causing Alzheimer's disease or other types of neurodegeneration, we may not realize that some of the same proteins are aggregating in our muscles, setting us up for muscle atrophy in old age.

23 Feb 2020

Abnormally low levels of a key protein detected in brains of young men with autism

Using cutting-edge imaging technology, researchers at Massachusetts General Hospital (MGH) have shown that the brains of young men with autism spectrum disorder (ASD) have low levels of a protein that appears to play a role in inflammation and metabolism.

23 Feb 2020

New C. elegans model will accelerate study of a rare disease

The model will permit to accelerate and reduce the price of the research, which is studying the mechanisms and the possible pharmacological targets for the neuronal alterations of this disease.

20 Feb 2020

Study reveals how overexposure to fluoride causes defects in tooth enamel

Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel- a novel explanation for how dental fluorosis, a condition caused by overexposure to fluoride during childhood, arises.

18 Feb 2020

Live-cell imaging provides new insights into dynamic structure of mitochondria

As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. Until now, it has been assumed that these functions underlie a static structure of mitochondrial membranes.

18 Feb 2020

Plant-based diets improve heart health via the gut microbiome

A new study published in February 2020 in the Journal of the American College of Cardiology reports that a reduced intake of animal-based foods and a diet based on plants can result in a lower risk of coronary heart disease (CHD) by influencing the gut microbiome pattern to favor beneficial species.

17 Feb 2020

Targeting regulatory T cells could boost the effects of cancer immunotherapy

A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor.

17 Feb 2020

Drinking cocoa could relieve peripheral arterial disease

Someday, according to a new study, doctors might prescribe chocolate or cocoa to help patients with peripheral arterial disease to walk easier. The study published in February 2020 in the journal Circulation Research of the American Heart Association (AHA) reports a significant improvement in walking distance in patients following regular cocoa consumption.

16 Feb 2020

Combination of green tea extract and exercise mitigates fatty liver disease in mice

The combination of green tea extract and exercise reduced the severity of obesity-related fatty liver disease by 75% in mice fed a high-fat diet, according to Penn State researchers, whose recent study may point to a potential health strategy for people.

16 Feb 2020

Cocoa consumption may improve walking performance in peripheral artery disease patients

Consumption of cocoa may improve walking performance for patients with peripheral artery disease, according to the results of a small, preliminary, phase II research trial published today in the American Heart Association's journal Circulation Research.

14 Feb 2020

Light-activated protein restores mitochondrion function in fruit fly model of Parkinson’s disease

A light-sensitive protein can restore mitochondria function in fruit flies bearing a gene mutation associated with Parkinson’s disease and relieve its symptoms, report researchers at Juntendo University in the journal Communications Biology.

13 Feb 2020

Mysterious virus found in Brazil puzzles scientists with its unique genetic makeup

A team of Brazilian scientists discovered a puzzling new virus made of genetic material never seen before. But the virus won’t pose a serious health threat to humanity since it seems to only hunt amoebas.

12 Feb 2020

Researchers identify control of a mitochondrial protective mechanism

Mitochondria are known as the "powerhouses" of cells. However, under critical pathophysiological conditions, they can use cellular energy for self-preservation.

12 Feb 2020

Study lays foundation for translating mitochondrial biology into clinical applications

A study led by The University of Texas MD Anderson Cancer Center furthered understanding about mitochondria, the cell components known as the "powerhouse of the cell." Knowing more about the genome is crucial given that mitochondria play important roles in tumorigenesis.

6 Feb 2020

Gut microbes in wasps help overcome pesticides

An intriguing study published in February 2020 in the journal Cell Host & Microbe reports that when wasps are exposed to atrazine, a commonly used pesticide, the gut microbiome undergoes changes that help them overcome the ill-effects of the exposure. In addition, the changes are passed on to the offspring, which means that the next generation will also inherit atrazine resistance even without being exposed to the chemical.

4 Feb 2020

Defective ATP13A2 gene can lead to Parkinson's disease, shows study

Biomedical scientists at KU Leuven have discovered that a defect in the ATP13A2 gene causes cell death by disrupting the cellular transport of polyamines.

30 Jan 2020

Research uncovers disease-aggravating mutation in mouse model of GRACILE syndrome

The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome. This discovery provides a new tool for studies of mitochondrial diseases.

29 Jan 2020

Mitochondria News and Research

Increasing energy supply within injured spinal cord nerves could help them heal

Researchers explore the role of SLC25A32 in cancer cell proliferation

Switching what heart cells consume could help them regenerate

Researchers discover glial cells that control stress response, extend lifespan in worms

Abnormally low levels of a key protein detected in brains of young men with autism

New C. elegans model will accelerate study of a rare disease

Study reveals how overexposure to fluoride causes defects in tooth enamel

Live-cell imaging provides new insights into dynamic structure of mitochondria

Plant-based diets improve heart health via the gut microbiome

Targeting regulatory T cells could boost the effects of cancer immunotherapy

Drinking cocoa could relieve peripheral arterial disease

Combination of green tea extract and exercise mitigates fatty liver disease in mice

Cocoa consumption may improve walking performance in peripheral artery disease patients

Light-activated protein restores mitochondrion function in fruit fly model of Parkinson’s disease

Mysterious virus found in Brazil puzzles scientists with its unique genetic makeup

Researchers identify control of a mitochondrial protective mechanism

Study lays foundation for translating mitochondrial biology into clinical applications

Gut microbes in wasps help overcome pesticides

Defective ATP13A2 gene can lead to Parkinson's disease, shows study

Research uncovers disease-aggravating mutation in mouse model of GRACILE syndrome

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