Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Stem-cell-derived brain cells hold promise for Alzheimer's, Parkinson's research

Researchers at the University of Wisconsin–Madison have identified a protein key to the development of a type of brain cell believed to play a role in disorders like Alzheimer's and Parkinson's diseases and used the discovery to grow the neurons from stem cells for the first time.

17 Nov 2023

New understanding of lung cancer cells' 'memories' suggests novel treatment approach

A new understanding of lung cancer cells' "memories" suggests a new strategy for improving treatment, Memorial Sloan Kettering Cancer Center (MSK) researchers have found.

17 Nov 2023

Researchers identify a promising new strategy for glaucoma cell replacement therapy

Glaucoma is one of the leading causes of blindness worldwide, and vision loss, due to the loss of retinal ganglion cells (RGCs), cannot currently be reversed with any treatment.

17 Nov 2023

Nerve-immune system cross-talk: Key to zebrafish heart regeneration

Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers led by Suphansa Sawamiphak from the Max Delbrück Center now report in the journal Developmental Cell.

17 Nov 2023

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

16 Nov 2023

Long-term monitoring of gene therapy patients crucial for safety, study says

Medical research has shown promising results regarding the potential of gene therapy to cure genetic conditions such as sickle cell disease and the findings of this study, published in Nature Medicine, offer important new insights into processes happening in the body after treatment.

16 Nov 2023

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

The R136S genetic mutation protected against apolipoprotein E4 (APOE4)-induced late-onset Alzheimer’s disease (LOAD).

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Study reveals mechanisms restricting oncogene-driven skin cancer formation

To form a cancer, cells need to accumulate oncogenic mutations that confer tumor-initiating properties.

15 Nov 2023

Microglia found to play crucial role in early human brain development

An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development.

14 Nov 2023

Bioengineered human heart muscle cells and micro-tissues take flight to space

Mount Sinai's Cardiovascular Research Institute is sending bioengineered human heart muscle cells and micro-tissues into space for the first time on NASA's 29th SpaceX commercial resupply services mission, which launched Thursday, November 9.

14 Nov 2023

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

14 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Autologous stem cell transplant shows promise for young patients with severe juvenile systemic sclerosis

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that patients with refractory juvenile systemic sclerosis improved significantly on nearly all measures for two years following autologous stem cell transplant.

10 Nov 2023

Study reveals early role of SYNGAP1 gene in brain development

The gene SYNGAP1, the variants of which are top risk factors for Autism Spectrum Disorder (ASD), has previously unappreciated effects on the developing brain, according to a new study published in Nature Neuroscience.

9 Nov 2023

NYU Langone Health performs the world's first whole-eye and partial-face transplant for military veteran

A surgical team from NYU Langone Health performed the world's first whole-eye and partial-face transplant for a 46-year-old military veteran from Arkansas who survived a work-related high-voltage electrical accident.

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Research brings the prospect of injection-free treatment closer for people with diabetes

A University of Alberta team has developed a new step to improve the process for creating insulin-producing pancreatic cells from a patient's own stem cells, bringing the prospect of injection-free treatment closer for people with diabetes.

7 Nov 2023

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

Stem Cells News and Research

Further Reading

Stem-cell-derived brain cells hold promise for Alzheimer's, Parkinson's research

New understanding of lung cancer cells' 'memories' suggests novel treatment approach

Researchers identify a promising new strategy for glaucoma cell replacement therapy

Nerve-immune system cross-talk: Key to zebrafish heart regeneration

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Long-term monitoring of gene therapy patients crucial for safety, study says

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals mechanisms restricting oncogene-driven skin cancer formation

Microglia found to play crucial role in early human brain development

Bioengineered human heart muscle cells and micro-tissues take flight to space

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

UCI researchers discover gene critical for muscle repair

Autologous stem cell transplant shows promise for young patients with severe juvenile systemic sclerosis

Study reveals early role of SYNGAP1 gene in brain development

NYU Langone Health performs the world's first whole-eye and partial-face transplant for military veteran

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Research brings the prospect of injection-free treatment closer for people with diabetes

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

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