Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.
A standard laboratory tool for measuring pharmacological activity of biological substances and performing other related tests may soon be replaced by a new miniaturized bioassay that will be faster, cheaper and more efficient for scientists to use, with new technology developed by Singapore's Institute of Bioengineering and Nanotechnology (IBN).
The editors of Tissue Engineering asked 24 leaders in the field what critical steps are needed for tissue engineering to achieve broad critical success by the year 2021 and published their findings in the December 2007 issue (Volume 13, Number 12).
Human embryonic stem cells can be genetically manipulated to help select out desirable cell types, according to a University of Nottingham study published online in Molecular Therapy.
Each year, pharmaceutical companies invest millions of dollars to test drugs, many of which will never reach the market because of side effects found only during human clinical trials.
Slow or troubled healing processes are one of the many negative outcomes of diabetes and many other human diseases.
Researchers of the BIOMAT (Biomaterials Centre) of the Universidad de La Habana have obtained an injectable macro-porous material, useful for the treatment of degenerative diseases such as osteoporosis, to refill bone cavities and in stomatology.
The benefits of applying technological know how to patient care were demonstrated by Prime Minister Gordon Brown at Imperial College London.
The new Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM) will be officially opened at the University of Nottingham on the 21st September, 2007 by Sir Keith O’Nions, Director General Science and Innovation at the Department for Innovation, Universities and Skills.
A team of Brown University biomedical engineers has invented a 3-D Petri dish that can grow cells in three dimensions, a method that promises to quickly and cheaply produce more realistic cells for drug development and tissue transplantation.
Green chemistry is being employed to develop revolutionary drug delivery methods that are more effective and less toxic - and could benefit millions of patients.
Scientists in Australia have found a way of identifying probable stem cells in the lining of women's wombs. The finding opens up the possibility of using the stem cells for tissue engineering applications such as building up natural tissue to repair prolapsed pelvic floors.
Infants and children receiving artificial heart-valve replacements face several repeat operations as they grow, since the since the replacements become too small and must be traded for bigger ones.
Rice University biomedical engineers have developed a new technique for growing cartilage from human embryonic stem cells, a method that could be used to grow replacement cartilage for the surgical repair of knee, jaw, hip, and other joints.
Blocking a naturally occurring inhibitor of bone formation accelerates healing of skull defects in mice, say researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital. The finding advances the understanding of how the skeleton develops and opens new therapeutic avenues for many of the disorders that are expected to afflict aging baby boomers.
A research group led by Dr. Cato T. Laurencin, with faculty representing five departments at the University of Virginia, will work on a first-of-its kind, $2 million grant project as they explore novel methods for the regeneration of musculoskeletal tissues.
Damaged or diseased vocal cords can forever change and even silence the voices we love, from a family member's to a famous personality's.
A $20-million deal announced to license Canadian stem cell technology in the U.S. underscores the Toronto area's global leadership in stem cell research.
University of Pittsburgh School of Medicine investigators have engineered artificial blood vessels from muscle-derived stem cells (MDSCs) and a biodegradable polymer that exhibit extensive remodeling and remain free of blockages when grafted into rats.
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual metastasis.
Researchers at the University of Pittsburgh School of Medicine have successfully isolated and cultured human hematopoietic stem cells from fat, or adipose, tissue, suggesting that they have found another important source of cells for reconstituting the bone marrow of patients undergoing intensive radiation therapy for blood cancers.
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