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Bionomics initiates BNC210 Phase 1b clinical trial in healthy volunteers

Bionomics Limited has initiated a Phase 1b clinical trial in healthy volunteers of BNC210, the Company's drug candidate in development for the treatment of anxiety and depression.

2 Feb 2015

RTI-HS, FDA partner to study patients' preferences that contributed to approval of new obesity device

RTI Health Solutions, a business unit of RTI International, partnered with the U.S. Food and Drug Administration to conduct a study on patients' preferences which contributed to the Agency's regulatory decision to approve the Maestro Rechargeable System, a first-of-kind device to treat obesity.

2 Feb 2015

Study examines why hydroxyurea yields mixed results in children with sickle cell disease

Electronic medication monitoring caps may help physicians put together the puzzle of why children taking a medicine that promises to curb sickle cell disease are showing mixed, confusing results.

2 Feb 2015

Researchers are developing stress-eating smartphone app with NIH support

Researchers at UMass Medical School and Worcester Polytechnic Institute are developing a stress-eating smartphone app that will help users better understand why they overeat, with the support of a $2 million award from the National Institutes of Health.

2 Feb 2015

ABIVAX doses first HIV positive patient in ABX464 Phase IIa clinical trial

ABIVAX, a leading clinical stage biotech company developing and commercialising anti-viral compounds and human vaccines, today announced that enrolment has been initiated and the first HIV positive patient dosed in a Phase IIa clinical trial of ABX464.

2 Feb 2015

Study identifies genetic basis of drug toxicity in leukemia patients of East Asian ancestry

January 26, 2015) About 10 percent of young leukemia patients of East Asian ancestry inherit a gene variation that is associated with reduced tolerance of a drug that is indispensable for curing acute lymphoblastic leukemia (ALL), the most common childhood cancer.

2 Feb 2015

Corn oil has greater effects on blood cholesterol than extra virgin olive oil

A study published in the January/February 2015 issue of the Journal of Clinical Lipidology indicates corn oil significantly reduces cholesterol more than extra virgin olive oil with favorable changes in both total and low-density lipoprotein (LDL) cholesterol.

31 Jan 2015

Inhibition of SIRT1 protein may hold promise for treatment of metastatic Ewing sarcoma

Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), led by Oscar Martínez Tirado participated in an international study which suggests inhibition of Sirtuin1 (SIRT1) protein as a future treatment option for metastatic Ewing sarcoma. The results of the study were published in the journal Cancer Research.

31 Jan 2015

Temple University Hospital participating in trial to test vibrating capsule for chronic constipation treatment

Chronic constipation is a common problem that affects approximately 15 percent of the U.S. population, according to the American Gastroenterological Association. It can be painful and lead to a reduction in a patient's quality of life. Temple University Hospital is the only hospital in the Philadelphia region participating in a nationwide clinical trial to test an innovative, vibrating capsule for patients with chronic constipation.

31 Jan 2015

Nuvo Research announces topline results from WF10 Phase 2 allergic rhinitis clinical trial

Nuvo Research Inc., a specialty pharmaceutical company with a diverse portfolio of topical and immunology products, today announced the results of its 16-week, double-blind, placebo-controlled, Phase 2 clinical trial conducted in Germany to compare the safety and efficacy of WF10 and its main constituents (sodium chlorite and sodium chlorate) with saline in patients with refractory allergic rhinitis and to compare the safety and efficacy of WF10 and its main constituents.

30 Jan 2015

TxCell receives milestone payment of EUR 1 million concerning Ovasave collaboration, license agreement from Trizell

TxCell SA, a biotechnology company developing innovative, cost-effective, personalized T-cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today the receipt of the latest milestone payment of EUR 1 million from the Ovasave collaboration option, development and license agreement from Trizell (Trizell Holding SA).

30 Jan 2015

Immunomic Therapeutics, Astellas Pharma sign license deal to develop LAMP-vax DNA vaccines

Immunomic Therapeutics, Inc. ("Immunomic Therapeutics"), a company developing next-generation vaccines based on the LAMP-vax platform, and Astellas Pharma Inc. ("Astellas") today announced they have entered into an exclusive license agreement for Japan to develop and commercialize JRC2-LAMP-vax, Immunomic Therapeutics' vaccine designed to treat allergies induced by Japanese red cedar pollen.

30 Jan 2015

Sebacia reports positive clinical results from two independent studies in people with acne

Sebacia, Inc., a company dedicated to delivering breakthrough topical treatments to advance dermatology, has announced the presentation of positive clinical results from two independent studies conducted in Europeinvestigating the use of Sebacia gold microparticles to treat acne.

29 Jan 2015

ADDF awards grant to support initiation of AGB101 Phase 3 trial for aMCI treatment

The Alzheimer's Drug Discovery Foundation announced today a $900,000 grant to AgeneBio, a pharmaceutical company developing innovative therapies for neurologic and psychiatric diseases. The grant will support the initiation of an FDA-registered Phase 3 clinical trial of AGB101, a new therapeutic treatment for amnestic mild cognitive impairment (aMCI).

28 Jan 2015

Alzheimer's Association announces new research grants to study potential drug therapies

Many academic researchers and pharmaceutical companies have identified new Alzheimer's drug therapy candidates, but lack the funding to move them into human testing. At the same time, few funding sources support early-phase clinical drug trials. As a result, too many promising studies stall out early in the discovery process.

28 Jan 2015

Bronchial thermoplasty for severe asthma: an interview with Dr. Rob Niven

Internationally, severe asthma is defined as anybody who is on maximum therapy, which has no measurable side effects, but still have symptoms of persistent asthma. In the UK, that effectively means people who require oral steroids for their asthma two or more times a year.

27 Jan 2015

genae announces acquisition of e-novex

genae, a global Contract Research Organization and services provider for the medical industries, announced today the acquisition of e-novex, a leading provider of electronic data tools that change medical research.

27 Jan 2015

Neuromod Devices, Irish Tinnitus Association announce launch of Tinnitus Awareness Week 2015

Saturday 31st of January sees the launch of Tinnitus Awareness Week. This year a public event will take place, hosted by The Neuromod Clinic in conjunction with the Irish Tinnitus Association. This free of charge event will take place at The Hermitage Medical Clinic, Lucan, Dublin at 10.30am on Saturday the 31st January.

27 Jan 2015

Morphine after tonsillectomy may be life threatening for children

Treating post-operative pain with morphine can cause life-threatening respiratory problems in some children who have had their tonsils and/or adenoids removed, new research has found.

27 Jan 2015

Bayer, MD Anderson partner to evaluate how a drug may affect patient's disease-related symptoms

When cancer patients take part in a clinical trial to develop new therapies, they and their physicians want to know how they will feel and function during treatment. A new collaboration between Bayer and The University of Texas MD Anderson Cancer Center will go straight to the patients to learn how certain investigational new drugs affect them.

24 Jan 2015

Clinical Trial News and Research

Bionomics initiates BNC210 Phase 1b clinical trial in healthy volunteers

RTI-HS, FDA partner to study patients' preferences that contributed to approval of new obesity device

Study examines why hydroxyurea yields mixed results in children with sickle cell disease

Researchers are developing stress-eating smartphone app with NIH support

ABIVAX doses first HIV positive patient in ABX464 Phase IIa clinical trial

Study identifies genetic basis of drug toxicity in leukemia patients of East Asian ancestry

Corn oil has greater effects on blood cholesterol than extra virgin olive oil

Inhibition of SIRT1 protein may hold promise for treatment of metastatic Ewing sarcoma

Temple University Hospital participating in trial to test vibrating capsule for chronic constipation treatment

Nuvo Research announces topline results from WF10 Phase 2 allergic rhinitis clinical trial

TxCell receives milestone payment of EUR 1 million concerning Ovasave collaboration, license agreement from Trizell

Immunomic Therapeutics, Astellas Pharma sign license deal to develop LAMP-vax DNA vaccines

Sebacia reports positive clinical results from two independent studies in people with acne

ADDF awards grant to support initiation of AGB101 Phase 3 trial for aMCI treatment

Alzheimer's Association announces new research grants to study potential drug therapies

Bronchial thermoplasty for severe asthma: an interview with Dr. Rob Niven

genae announces acquisition of e-novex

Neuromod Devices, Irish Tinnitus Association announce launch of Tinnitus Awareness Week 2015

Morphine after tonsillectomy may be life threatening for children

Bayer, MD Anderson partner to evaluate how a drug may affect patient's disease-related symptoms

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