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Weight loss most important factor for improving cardiovascular health in obese OSA patients

Obesity and obstructive sleep apnea (OSA) tend to co-exist and are associated with a variety of cardiovascular risk factors, including inflammation, insulin resistance, abnormal cholesterol, and high blood pressure. While effective therapies are available for OSA, researchers are still unclear about what interventions are most effective in reducing the burden of risk factors for cardiovascular disease associated with OSA in obese patients.

13 Jun 2014

New class of tumor-targeting agents can seek out dozens of solid tumors

Scientists at the University of Wisconsin Carbone Cancer Center (UWCCC) report that a new class of tumor-targeting agents can seek out and find dozens of solid tumors, even illuminating brain cancer stem cells that resist current treatments.

13 Jun 2014

Cranial ultrasound has greater sensitivity than temporal artery biopsy in diagnosis of GCA

A new study presented for the first time today at the European League Against Rheumatism Annual Congress (EULAR 2014), shows that cranial ultrasound has a greater sensitivity than temporal artery biopsy,* and a comparable specificity in the diagnosis of Giant Cell Arteritis (GCA).

13 Jun 2014

Scientists are now one step closer to pill against obesity

Obesity and diabetes are among the fastest growing health problems in the world, and the hunt is in for a pill that can fight the problem.

13 Jun 2014

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

Researchers at Benaroya Research Institute at Virginia Mason used cutting-edge tetramer technology developed at BRI to find the T cells that drive rheumatoid arthritis (RA). "By using tetramer technology, we were able to examine whether T cells in people with rheumatoid arthritis were increased in number or were unique in other ways," says BRI Associate Director Jane Buckner, MD, who led the study with BRI Tetramer Core Laboratory Manager Eddie James, PhD.

12 Jun 2014

Study supports proposal to screen all men with gout for presence of ED

A new study presented today at the European League Against Rheumatism Annual Congress showed that erectile dysfunction (ED) is present in most men with gout and is frequently severe.

12 Jun 2014

DNA methylation identified as potential anti-TNF response biomarker for RA

DNA methylation has been identified as a potential biomarker of response to etanercept and adalimumab in patients with rheumatoid arthritis (RA) according to preliminary results from one of the largest methylome-wide investigations of treatment response to anti-TNF therapies.

12 Jun 2014

Exercise transiently suppresses inflammation in rheumatic disease

Research findings presented today at the European League Against Rheumatism Annual Congress suggest that exercise transiently suppresses local and systemic inflammation, reinforcing the beneficial effects of exercise and the need for this to be regular in order to achieve clinical efficacy in rheumatic disease.

12 Jun 2014

Obese patients with rheumatoid arthritis have higher disease activity scores

A new study presented today at the European League Against Rheumatism Annual Congress showed that obese patients with rheumatoid arthritis (RA) have higher DAS (disease activity) scores than non-obese patients, irrespective of their disease stage.

12 Jun 2014

New research collaboration aims to develop better therapies for autoimmune diseases

Seattle Children's Research Institute and biotechnology company Kineta, Inc. today launched the Alliance for Children's Therapeutics (ACT), a first-of-its-kind pediatric research and funding collaboration designed to speed development of new medications for children and teens with lupus nephritis and other autoimmune diseases like multiple sclerosis, Type 1 diabetes and rheumatoid arthritis.

11 Jun 2014

Researchers find standard heart disease risk assessment tools for rheumatoid arthritis patients

Rheumatoid arthritis patients overall are twice as likely as the average person to develop heart problems. Pinpointing which rheumatoid arthritis patients need stepped-up heart disease prevention efforts has been a challenge; research by Mayo Clinic and others has found that standard heart disease risk assessment tools may underrate the danger a particular person faces.

11 Jun 2014

Bayer HealthCare seeks EU marketing authorization of EYLEA for macular edema following BRVO

Regeneron Pharmaceuticals, Inc. and Bayer HealthCare today announced that Bayer HealthCare has submitted an application to the European Medicines Agency (EMA) seeking marketing authorization in the European Union (EU) for EYLEA (aflibercept) Injection for the treatment of macular edema following branch retinal vein occlusion (BRVO).

11 Jun 2014

Celsus’ expert highlights serious side effects of topical corticosteroids

A 2013 Mayo Clinic study involving more than 140,000 patients revealed that skin disorders are the most common nonacute reason Americans seek health care.

9 Jun 2014

Antiviral therapy may prevent hepatitis B virus from developing into hepatocellular carcinoma

Researchers have found that antiviral therapy may be successful in preventing hepatitis B virus from developing into the most common form of liver cancer, hepatocellular carcinoma (HCC).

9 Jun 2014

Research findings on mTor, circadian rhythm, animal aging and FAT10 presented at AGE meeting

The 43rd Annual Meeting of the American Aging Association held May 30-June 2, 2014, at the Westin Riverwalk Hotel in San Antonio, Texas, featured the latest scholarship and research findings in the field of aging research from more than 70 leading experts.

6 Jun 2014

Lack of O2 in fat cells triggers inflammation and insulin resistance in obesity

Researchers at the University of California, San Diego School of Medicine have, for the first time, described the sequence of early cellular responses to a high-fat diet, one that can result in obesity-induced insulin resistance and diabetes.

6 Jun 2014

FCVB 2014 to feature cutting edge research in basic cardiovascular science

Cutting edge research in basic cardiovascular science will be presented at Frontiers in CardioVascular Biology (FCVB) 2014, held 4-6 July at the Palau de Congressos de Catalunya in Barcelona, Spain.

5 Jun 2014

New antibiotic proves effective in treating serious bacterial skin and skin-structure infections

A study published in today's New England Journal of Medicine reports that the antibiotic dalbavancin is as effective as vancomycin, the current standard-of-care antibiotic used to treat serious bacterial skin and skin-structure infections.

5 Jun 2014

New book documents groundbreaking studies on modified citrus pectin

One of the nation's leading writers on the use of naturopathic medicine has released a new book documenting groundbreaking studies on modified citrus pectin (MCP) and its application for addressing serious health issues like cancer, heart disease, chronic inflammation and fibrosis.

4 Jun 2014

Georgia State University establishes new research center to help fight obesity epidemic

The Center for Obesity Reversal, a new top-level research center at Georgia State University, has been established to foster research projects that will help fight the nation's obesity epidemic.

4 Jun 2014

Inflammation News and Research

Weight loss most important factor for improving cardiovascular health in obese OSA patients

New class of tumor-targeting agents can seek out dozens of solid tumors

Cranial ultrasound has greater sensitivity than temporal artery biopsy in diagnosis of GCA

Scientists are now one step closer to pill against obesity

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

Study supports proposal to screen all men with gout for presence of ED

DNA methylation identified as potential anti-TNF response biomarker for RA

Exercise transiently suppresses inflammation in rheumatic disease

Obese patients with rheumatoid arthritis have higher disease activity scores

New research collaboration aims to develop better therapies for autoimmune diseases

Researchers find standard heart disease risk assessment tools for rheumatoid arthritis patients

Bayer HealthCare seeks EU marketing authorization of EYLEA for macular edema following BRVO

Celsus’ expert highlights serious side effects of topical corticosteroids

Antiviral therapy may prevent hepatitis B virus from developing into hepatocellular carcinoma

Research findings on mTor, circadian rhythm, animal aging and FAT10 presented at AGE meeting

Lack of O2 in fat cells triggers inflammation and insulin resistance in obesity

FCVB 2014 to feature cutting edge research in basic cardiovascular science

New antibiotic proves effective in treating serious bacterial skin and skin-structure infections

New book documents groundbreaking studies on modified citrus pectin

Georgia State University establishes new research center to help fight obesity epidemic

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