Immune System News and Research

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International research effort reveals major insights into spread of West African Ebola epidemic

An international effort to analyze the entire database of Ebola virus genomes from the 2013-2016 West African epidemic reveals insights into factors that sped or slowed the rampage and calls for using real-time sequencing and data-sharing to contain future viral disease outbreaks.

12 Apr 2017

NIH study provides unprecedented detail on host response to Ebola virus disease

Analysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health (NIH) in 2015 found changes in antiviral and immune response genes that pinpointed key transition points in the response to infection.

12 Apr 2017

Gladstone scientists discover common mechanism that links neurodegeneration in young and old

Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), identified a common mechanism in two forms of neurodegeneration that affect young adults or the elderly.

12 Apr 2017

Vitamin B supplements can mitigate impact of fine particle pollution on cardiovascular disease

B vitamins can mitigate the impact of fine particle pollution on cardiovascular disease, according to new research conducted at Columbia University's Mailman School of Public Health.

12 Apr 2017

Human Vaccines Project, VUMC and Illumina team up to decipher genetic underpinnings of immune system

The Human Vaccines Project and Vanderbilt University Medical Center (VUMC) today announced that they joined forces with Illumina, Inc., to decipher the human immunome, the genetic underpinnings of the immune system.

12 Apr 2017

New transgenic mouse could help monitor potential dangers of emerging influenza viruses

Researchers in Germany have developed a transgenic mouse that could help scientists identify new influenza virus strains with the potential to cause a global pandemic.

10 Apr 2017

Scientists shed light on evolutionary arms race between CMV and immune system

Imaging CoE scientists have solved a 40-year old mystery and shed light on an evolutionary arms race played out between cytomegalovirus (CMV) and the immune system.

10 Apr 2017

New research sheds light on movement of white blood cells to sites of infection

One of the mysteries of the living body is the movement of cells - not just in the blood, but through cellular and other barriers.

10 Apr 2017

Programmed proteins could lead to inexpensive malaria vaccine

Despite decades of malaria research, the disease still afflicts hundreds of millions and kills around half a million people each year - most of them children in tropical regions.

10 Apr 2017

Viral trigger may underlie development of celiac disease

Reovirus, which commonly infects humans without causing any symptoms, may trigger an immune response to gluten that causes celiac disease, report US researchers.

10 Apr 2017

Microbiologists accurately predict evolution of HIV surface proteins using financial math models

What do particle diffusion in liquids and stock price prediction have to do with building a better HIV vaccine? According to University of Iowa microbiologist Hillel Haim, you can apply concepts from the first two to predict the evolution of HIV surface proteins, information that can then be used to design better vaccines.

7 Apr 2017

Immunologists discover how rescue proteins delay ‘executioner’ machinery that kills damaged cells

A research team led by St. Jude Children's Research Hospital immunologists has discovered how a set of proteins delays the "executioner" machinery that kills damaged or infected cells in a process called necroptosis.

7 Apr 2017

Study of interactions between chemokines pinpoints potential targets for treatment of inflammation

Signal molecules called chemokines often work in tandem to recruit specific sets of immune cells to sites of tissue damage.

7 Apr 2017

Researchers uncover critical pathway that helps pancreatic cancer cells turn off immune system

Researchers at NYU Langone Medical Center and its Perlmutter Cancer Center have uncovered a critical pathway by which pancreatic cancer cells turn off the immune system charged with attacking them. The findings appear in a paper published online in Nature Medicine April 10.

7 Apr 2017

Infection with reovirus could be key initiating event for developing celiac disease, study suggests

Infection with reovirus, a common but otherwise harmless virus, can trigger the immune system response to gluten that leads to celiac disease, according to new research from the University of Chicago and the University of Pittsburgh School of Medicine.

6 Apr 2017

Cancer uses immature immune cells as support system for successful metastasis, study shows

More typically, these immature immune cells might help us fight cancer, but scientists have now shown cancer can commandeer the cells to help it spread.

6 Apr 2017

Tumor necrosis factor may help control blood pressure, study suggests

Investigators at the Ted Rogers Centre for Heart Research have discovered a surprising new role for tumor necrosis factor (TNF): namely, that it is a major regulator of small blood vessel function, the key determinant of blood pressure. The study is published online today in Nature Communications.

6 Apr 2017

Researchers solve medical mystery through genetics

Researchers have identified the genetic mutation responsible for one patient's serious health problems, finally solving a medical mystery that has endured for over 30 years.

6 Apr 2017

Case Western Reserve University researchers aim to treat oral complications of HIV

While advances in HIV treatment have dramatically improved patient lifespans and quality of life, nagging side effects remain; among the most common is chronic inflammation--essentially, when an immune system imbalance causes the body to attack itself.

6 Apr 2017

Researchers develop stable brain implant based on anti-inflammatory coating

Complex neurotechnological devices are required to directly select and influence brain waves inside the skull's interior. Although it has become relatively easy to implement the devices, researchers are still faced with challenges when trying to keep them running properly in living organisms over time.

5 Apr 2017

Immune System News and Research

International research effort reveals major insights into spread of West African Ebola epidemic

NIH study provides unprecedented detail on host response to Ebola virus disease

Gladstone scientists discover common mechanism that links neurodegeneration in young and old

Vitamin B supplements can mitigate impact of fine particle pollution on cardiovascular disease

Human Vaccines Project, VUMC and Illumina team up to decipher genetic underpinnings of immune system

New transgenic mouse could help monitor potential dangers of emerging influenza viruses

Scientists shed light on evolutionary arms race between CMV and immune system

New research sheds light on movement of white blood cells to sites of infection

Programmed proteins could lead to inexpensive malaria vaccine

Viral trigger may underlie development of celiac disease

Microbiologists accurately predict evolution of HIV surface proteins using financial math models

Immunologists discover how rescue proteins delay ‘executioner’ machinery that kills damaged cells

Study of interactions between chemokines pinpoints potential targets for treatment of inflammation

Researchers uncover critical pathway that helps pancreatic cancer cells turn off immune system

Infection with reovirus could be key initiating event for developing celiac disease, study suggests

Cancer uses immature immune cells as support system for successful metastasis, study shows

Tumor necrosis factor may help control blood pressure, study suggests

Researchers solve medical mystery through genetics

Case Western Reserve University researchers aim to treat oral complications of HIV

Researchers develop stable brain implant based on anti-inflammatory coating

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