Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Disrupting tuft cell development may be a new way to treat deadly lung cancer

Cold Spring Harbor Laboratory Professor Christopher Vakoc's team discovered in 2018 a new type of small-cell lung cancer. The cancer originates from cells known as tuft cells.

22 Jun 2022

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T–cell therapy for treatment of solid tumors.

22 Jun 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Gene expression regulation by N6-methyladenosine

A recent study published in Molecular Cell reviewed the control of gene expression by N6-methyladenosine (m6A), a modified nucleotide in the messenger ribonucleic acid (mRNA).

22 Jun 2022

Researchers map cancer driver mutations across the human genome

In a recent study published in Nature Biotechnology, researchers explored the causes of cancer by mapping somatic mutation rates across the human genome.

22 Jun 2022

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

A recent study published in the Cell Reports journal analyzed immune ecology at the placenta in mild or asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy.

22 Jun 2022

New technology can revitalize the bactericidal effects of conventional antibiotics in MDR E.coli infections

A research team led by Professor Kelvin Yeung Wai-kwok from the Department of Orthopaedics and Traumatology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) has designed a non-invasive technology to revitalize the bactericidal effects of conventional antibiotics in multidrug-resistant (MDR)Escherichia coli (E. coli)-associated deep tissue infections, such as urinary tract and peritoneal infections.

22 Jun 2022

Potential SARS-CoV-2 antivirals based on host miRNAs

A recent research paper posted to the bioRxiv* preprint server demonstrated micro ribonucleic acids (miRNAs) as potential antiviral options against various coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

21 Jun 2022

A longitudinal population-based study of COVID-19 in the UK

In a recent study posted to the medRxiv* pre-print server, researchers identified potential risk factors and incident symptoms of coronavirus disease 2019 (COVID-19) in the general population of the United Kingdom (UK).

21 Jun 2022

Study shows molecular details of HIV-1 assembly and viral envelope protein incorporation

Assembly of HIV-1, which causes AIDS, takes place on the inner plasma membrane leaflet of infected cells, a geometric building process that creates hexamers out of trimers of the viral Gag protein, as guided by Gag's N-terminal matrix domain.

21 Jun 2022

Scientists discover 15 additional genetic mutations linked to KCNK9 imprinting syndrome

A collaborative team of scientists led by Mayo Clinic's Center for Individualized Medicine has discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome.

21 Jun 2022

Researchers investigate the cell adhesion behavior on spider silk for medical use

Silk has been cultivated for centuries by domesticated silkworms, but it has been difficult to commercially produce spider silk in bulk due to their cannibalistic tendencies.

21 Jun 2022

Erectile dysfunction drugs may be able to boost the effect of chemotherapy in esophageal cancer

A group of drugs commonly used to treat erectile dysfunction may be able to boost the effect of chemotherapy in esophageal cancer, according to new research funded by Cancer Research UK and the Medical Research Council.

21 Jun 2022

Protein produced by soft-tissue sarcomas makes immune cells ‘go bad’

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting.

21 Jun 2022

Computer simulation model helps understand why chemotherapy resistance occurs

Understanding why and how chemotherapy resistance occurs is a major step toward optimizing treatments for cancer.

21 Jun 2022

Research may pave the way for a future test to diagnose ALS

Amyotrophic lateral sclerosis (ALS) is a progressive disease of the nervous system. It affects nerve cells in the brain and spinal cord called motor neurons.

21 Jun 2022

Researchers discover the skin's natural protection from nighttime bacterial invasion in mice

Researchers at Kyoto University have discovered the skin's natural protection from nighttime bacterial invasion in mice, which may provide a basis for eventually developing a drug treatment.

21 Jun 2022

A class of protein-cleaving enzymes suspected to play a role in hereditary brain disease

Similar to Alzheimer's disease, the hereditary disease spinocerebellar ataxia type 17 (SCA17) leads to the destruction of brain nerve cells and the premature death of patients.

21 Jun 2022

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

Researchers comparatively assessed the generation of B lymphocyte-mediated antibody responses and T lymphocyte-mediated cellular responses between mRNA BNT162b vaccinees and mild COVID-19 patients.

21 Jun 2022

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

A new study reported four cases of Myelin Oligodendrocyte Glycoprotein-Associated Disorder that commenced after SARS-CoV-2 infection.

21 Jun 2022

Protein News and Research

Further Reading

Disrupting tuft cell development may be a new way to treat deadly lung cancer

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

Gene expression regulation by N6-methyladenosine

Researchers map cancer driver mutations across the human genome

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

New technology can revitalize the bactericidal effects of conventional antibiotics in MDR E.coli infections

Potential SARS-CoV-2 antivirals based on host miRNAs

A longitudinal population-based study of COVID-19 in the UK

Study shows molecular details of HIV-1 assembly and viral envelope protein incorporation

Scientists discover 15 additional genetic mutations linked to KCNK9 imprinting syndrome

Researchers investigate the cell adhesion behavior on spider silk for medical use

Erectile dysfunction drugs may be able to boost the effect of chemotherapy in esophageal cancer

Protein produced by soft-tissue sarcomas makes immune cells ‘go bad’

Computer simulation model helps understand why chemotherapy resistance occurs

Research may pave the way for a future test to diagnose ALS

Researchers discover the skin's natural protection from nighttime bacterial invasion in mice

A class of protein-cleaving enzymes suspected to play a role in hereditary brain disease

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

SARS-CoV-2 infection may be a trigger of myelin oligodendrocyte glycoprotein-associated disorder

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