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COVID mRNA vaccines show diminished neutralization responses against Omicron

Researchers report an overview of antibody neutralization by all currently approved vaccines against the SARS-CoV-2 Omicron, Beta, and Delta VOCs.

29 Dec 2021

Researchers suggest hybrid convalescent plasma therapy neutralizes the omicron variant

New research suggests convalescent plasma from unvaccinated donors is not effective against the Omicron variant, however, “hybrid” convalescent plasma from donors who recovered from COVID-19 infection and are vaccinated provides considerable antibody protection.

29 Dec 2021

Animal study suggests Omicron is less infectious than previous SARS-CoV-2 strains

A new study suggests the Omicron (B.1.1.529) variant is not as infectious as scientists initially assumed.

29 Dec 2021

Study suggests saliva swabs may be more suitable for omicron detection

New study findings reveal that saliva samples are more useful than mid-turbinate samples for the accurate detection of omicron infection.

29 Dec 2021

Impact of an omicron outbreak at a private gathering in the Faroe Islands

New findings suggest that the Omicron variant has potent immune-escape capabilities, putting even newly boosted patients at risk of infection.

29 Dec 2021

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

A new study found that the presence of a subset of antibodies with broad neutralizing activities against all circulating variants of concern in the three-dose vaccines' memory B-derived antibody repertoire suggests that the Omicron/future variants infection may elicit selective and rapid recall of humoral responses, conferring secondary protection directed by memory etched in the immune system.

29 Dec 2021

Exploring immunogenicity and safety after a homologous booster dose of SARS-CoV-2 recombinant spike protein vaccine

Research suggests that a single booster dose of NVX-CoV2373 given approximately six months after the primary series induced significant increases in humoral antibodies, while also exhibiting an acceptable safety profile.

29 Dec 2021

Booster dose of mRNA vaccines found crucial in protecting against SARS-CoV-2 Omicron variants

A new study shows that Omicron is more infectious than any of the other variants and that booster vaccines, especially mRNA vaccines, are capable of neutralizing Omicron variants of pseudoviruses.

29 Dec 2021

New techniques enable visualization of DNA repair machinery in detail

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects and repair genetic damage is at work to prevent DNA mutations and diseases such as cancer.

29 Dec 2021

New biodegradable smart food packaging material helps kill harmful microbes

A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) and Harvard T.H. Chan School of Public Health, US, has developed a 'smart' food packaging material that is biodegradable, sustainable and kills microbes that are harmful to humans. It could also extend the shelf-life of fresh fruit by two to three days.

29 Dec 2021

New optogenetic tool uses focused light to reduce actin and myosin-based contractile force

Cell generated force plays essential roles in a wide range of biological processes, such as cell motility, cytokinesis, and tissue morphogenesis. In a study published in Nature Communications, a research team led by the Division of Quantitative Biology at the National Institute for Basic Biology in Japan has successfully developed "OptoMYPT"：an optogenetic tool that utilizes focused light to reduce actin and myosin-based contractile force.

29 Dec 2021

Pregnant women should not delay COVID-19 vaccination until late pregnancy, study suggests

COVID-19 vaccination of expectant mothers elicits levels of antibodies to the SARS-CoV-2 outer "spike" protein at the time of delivery that don't vary dramatically with the timing of vaccination during pregnancy and thus don't justify delaying vaccination, according to a study from researchers at Weill Cornell Medicine and NewYork-Presbyterian.

28 Dec 2021

Estimating the epidemic potential of SARS-CoV-2 Omicron variant in South Korea

Researchers in South Korea and France have conducted an analysis on individuals infected with Omicron variant (B.1.1.529) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to estimate the epidemic potential and long-term prospects of this virus in circulation. They have found that the basic reproduction number (R0) for this variant is 1.90, while the mean serial interval is 2.22 days.

28 Dec 2021

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

Now in new research, scientists from the University of Leicester have been investigating how these mutations alter the affinities of RBDs to ACE2.

28 Dec 2021

SARS-CoV-2 infection induces robust and cross-reactive immune responses in children

Researchers compare the convalescent humoral and cellular immune responses between children and adults infected with SARS-CoV-2.

28 Dec 2021

Study highlights importance of positive and negative selection in evolution of SARS-CoV-2 variants

Researchers from the University of Colorado Anschutz Medical Campus have been investigating the changes imparted on the Gamma variant by three RBD mutations.

28 Dec 2021

Third BNT162b2 dose effectively neutralizes SARS-CoV-2 Omicron pseudovirus

The findings reveal that the Omicron neutralizing titers induced by the third vaccine dose are comparable to that achieved against the original Wuhan strain (wild-type SARS-CoV-2) by the two-dose regimen. The study is currently available on the medRxiv* preprint server while awaiting peer review.

28 Dec 2021

Protein C News and Research

COVID mRNA vaccines show diminished neutralization responses against Omicron

Researchers suggest hybrid convalescent plasma therapy neutralizes the omicron variant

Animal study suggests Omicron is less infectious than previous SARS-CoV-2 strains

Study suggests saliva swabs may be more suitable for omicron detection

Impact of an omicron outbreak at a private gathering in the Faroe Islands

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

Exploring immunogenicity and safety after a homologous booster dose of SARS-CoV-2 recombinant spike protein vaccine

Booster dose of mRNA vaccines found crucial in protecting against SARS-CoV-2 Omicron variants

New techniques enable visualization of DNA repair machinery in detail

New biodegradable smart food packaging material helps kill harmful microbes

New optogenetic tool uses focused light to reduce actin and myosin-based contractile force

Pregnant women should not delay COVID-19 vaccination until late pregnancy, study suggests

Estimating the epidemic potential of SARS-CoV-2 Omicron variant in South Korea

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

SARS-CoV-2 infection induces robust and cross-reactive immune responses in children

Study highlights importance of positive and negative selection in evolution of SARS-CoV-2 variants

Third BNT162b2 dose effectively neutralizes SARS-CoV-2 Omicron pseudovirus

Study suggests spike mutation makes SARS-CoV-2 Omicron milder

Structural blueprint of nanoparticles developed to target neutrophils responsible for acute lung inflammation

Researchers discover antibodies that neutralize omicron and other SARS-CoV-2 variants

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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