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The Emerging Field of Gene Therapy with Adeno-Associated Viruses

In this interview, Arnaud Delobel, the R&D and Innovation Director at Quality Assistance talks to NewsMed-LS about the emerging field of gene therapy with adeno-associated viruses (AAV).

From Waters | Wyatt Technology 18 Oct 2022

Bioinformatics analysis of monkeypox virus-host cell interactions

A recent study posted to the bioRxiv* preprint server reported the interaction between monkeypox and human cells. Molecular sequences were screened to identify differentially expressed genes (DEGs) and their associated signal pathway, expression regulation, and metabolic pathways.

18 Oct 2022

Deep learning software helps to identify miniscule bacteria in microscopy images

Omnipose, a deep learning software, is helping to solve the challenge of identifying varied and miniscule bacteria in microscopy images.

17 Oct 2022

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

UVA Health researchers have discovered a molecule in the brain responsible for orchestrating the immune system's responses to Alzheimer's disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body's ability to fight those and other devastating neurological diseases.

17 Oct 2022

Researchers identify a new gene essential to colon cancer growth

Researchers at Mount Sinai's Tisch Cancer Institute have identified a new gene that is essential to colon cancer growth and found that inflammation in the external environment around the tumor can contribute to the growth of tumor cells.

17 Oct 2022

Genetic signature predicts tumor metastases and patient survival in clear cell kidney cancer

Among patients with kidney cancer, the activity of four specific genes in the cancer cells seems to be able to predict the risk of the tumor spreading and the patient's chances of survival.

17 Oct 2022

Novel drug target for triple-negative breast cancer discovered

Research led by Dr. Suresh Alahari, Professor of Biochemistry at LSU Health New Orleans' Schools of Medicine and Graduate Studies, reports a combination of a novel small inhibitory molecule and an FDA-approved chemotherapy drug suppresses the growth of triple-negative breast cancer cells synergistically.

17 Oct 2022

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

In a new study, researchers determined plasma signatures of proteins related to or derived from platelets in acute isolated pulmonary embolism (iPE) and deep vein thrombosis-associated PE (DVT-PE), compared to isolated DVT (iDVT).

17 Oct 2022

Scientists use enhanced environmental surveillance for poliovirus type 2 detection in London sewage samples

In a new study, researchers investigated molecular properties of type 2 poliovirus (PV) isolates obtained from sewage samples (SS) to detect PV transmission in communities.

17 Oct 2022

Study reviews hydroxychloroquine and remdesivir antiviral potency against SARS‐CoV‐2

In a new study, researchers outlined the synthesis and the possible mechanism of action (MOA) of two potential severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) repurposing drug candidates.

17 Oct 2022

Scientists identify group of genes shared between COVID-19 and diabetic kidney disease

Scientists identified five hub genes that might be associated with severe COVID-19 outcomes in patients with diabetic kidney disease.

17 Oct 2022

Increased TMPRSS2 expression in tongue tissue of females and alcohol drinkers identified as a potential risk factor for SARS-CoV-2 infection

Researchers explored the association between the expressions of the ACE-2 receptor and TMPRSS2 in the tongue tissue and dysgeusia during SARS-CoV-2 infections.

17 Oct 2022

What is the impact of COVID-19 and organophosphates on cardiac health?

In a new study, researchers discussed the impacts of organophosphates (OP) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on cardiovascular (CVS) health.

17 Oct 2022

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

A new review discussed the applications of single-cell ribonucleic acid sequencing (scRNA-seq) in understanding autoimmune disorders.

17 Oct 2022

Exploring molecular docking and molecular dynamics simulations as advanced tools for novel antiviral drug discovery

Researchers presented an overview of factors influencing emerging infectious diseases. They also highlighted the importance of molecular dynamic (MD) simulations and molecular docking (MDO) analysis for combating these diseases.

17 Oct 2022

Could COVID-19 infections trigger a relapse of mycosis fungoides or other cutaneous T-cell lymphomas?

Recently, authors highlighted the potential role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in triggering the relapse of mycosis fungoides, a type of cutaneous T-cell lymphoma.

17 Oct 2022

How the ‘love hormone’ oxytocin may have heart-healing properties

In this interview, News Medical speaks to Dr. Aitor Aguirre, Assistant Professor of Biomedical Engineering at Michigan State University, about how the ‘love hormone’ oxytocin may provide heart-healing properties.

17 Oct 2022

Selective immunoglobulin A deficiency a risk factor for severe COVID-19

In a recent study published in The Journal of Allergy and Clinical Immunology, researchers in New Zealand gathered evidence to show that selective immunoglobulin A deficiency (sIgAD) is an understated risk factor for severe coronavirus disease 2019 (COVID-19).

17 Oct 2022

A rare case of Hashimoto encephalopathy after COVID vaccination

In a recent ‘Letter to the Editor’ published in the English edition of the journal Neurologandiacute, researchers reported the rare occurrence of Hashimoto encephalopathy in a recipient of the (COVID-19) vaccine Spikevax. Spikevax, research name mRNA-1273, is a COVID-19 vaccine based on the messenger ribonucleic acid (mRNA) technology.

16 Oct 2022

High TNF receptors levels could predict COVID-19 mortality and disease severity

High levels of TNFR might successfully predict the increased severity of COVID-19.

16 Oct 2022

B Cell News and Research

The Emerging Field of Gene Therapy with Adeno-Associated Viruses

Bioinformatics analysis of monkeypox virus-host cell interactions

Deep learning software helps to identify miniscule bacteria in microscopy images

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

Researchers identify a new gene essential to colon cancer growth

Genetic signature predicts tumor metastases and patient survival in clear cell kidney cancer

Novel drug target for triple-negative breast cancer discovered

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

Scientists use enhanced environmental surveillance for poliovirus type 2 detection in London sewage samples

Study reviews hydroxychloroquine and remdesivir antiviral potency against SARS‐CoV‐2

Scientists identify group of genes shared between COVID-19 and diabetic kidney disease

Increased TMPRSS2 expression in tongue tissue of females and alcohol drinkers identified as a potential risk factor for SARS-CoV-2 infection

What is the impact of COVID-19 and organophosphates on cardiac health?

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

Exploring molecular docking and molecular dynamics simulations as advanced tools for novel antiviral drug discovery

Could COVID-19 infections trigger a relapse of mycosis fungoides or other cutaneous T-cell lymphomas?

How the ‘love hormone’ oxytocin may have heart-healing properties

Selective immunoglobulin A deficiency a risk factor for severe COVID-19

A rare case of Hashimoto encephalopathy after COVID vaccination

High TNF receptors levels could predict COVID-19 mortality and disease severity

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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