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BIOCIUS and Agilent launch RF360 High Resolution System for high-throughput screening of in vitro ADME assays

BIOCIUS Life Sciences, Inc. and Agilent Technologies Inc. today announced the launch of the RF360 High Resolution System for high-throughput screening of in vitro ADME assays. Combining the accurate mass capabilities of Agilent's time-of-flight (TOF) mass spectrometers and the unprecedented sample processing speed of RapidFire® technology, the instrument revolutionizes in vitro ADME analysis by eliminating the method development bottleneck in drug discovery.

From Evident Corporation - Life Sciences 20 May 2010

New study uses NMR in drug design

A new study by a team of researchers led by Jeffrey Peng, assistant professor of chemistry and biochemistry at the University of Notre Dame, is using Nuclear Magnetic Resonance, to move drug design into groundbreaking consideration of the dynamic flexibility of drugs and their targets.

20 May 2010

Androgen receptors promote hepatitis B virus in growth and development of hepatoma cells

Dr. Ming-Heng Wu of the Institute of Basic Medical Sciences at National Cheng Kung University (NCKU), Taiwan, in collaboration with Prof. Chawnshang Chang's laboratory of University of Rochester (UR), United States, have discovered that androgen receptors (AR) can promote hepatitis B virus-induced hepatocarcinogenesis through modulation of hepatitis B virus (HBV) RNA transcription.

20 May 2010

Scientists present data on denufosol tetrasodium for CF at ATS 2010 International Conference

Inspire Pharmaceuticals, Inc. announced today that Inspire scientists and collaborators will present data on denufosol tetrasodium, an investigational therapy for cystic fibrosis, during an oral presentation at the American Thoracic Society 2010 International Conference May 14 - 19, 2010 in New Orleans, LA.

20 May 2010

2010 funding program for Inova Life Sciences - George Mason University research collaboration open

What do you get when you mix a world-class health system with an innovative, entrepreneurial university? A very successful research collaboration.

20 May 2010

Loyola University Chicago introduces new online doctorate degree program in bioethics

Classes have begun for Loyola University Chicago's new online doctorate degree program in bioethics, designed to provide advanced training in the ethical issues surrounding the complexities of modern medical research and clinical care.

20 May 2010

FDA grants 510(k) market clearance for EraGen's MultiCode-RTx HSV 1&2 Kit

EraGen Biosciences Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) market clearance for EraGen's MultiCode®-RTx HSV 1&2 Kit.

20 May 2010

Results from Phase 1 clinical trials of TRC105, TRC102, and TRC093 to be presented at ASCO 2010

TRACON Pharmaceuticals, a biotechnology company that develops targeted therapies for oncology and ophthalmology, announced today that results from Phase 1 clinical trials of TRC105, TRC102, and TRC093 will be presented at the annual meeting of the American Society of Clinical Oncology on June 5-7, 2010 in Chicago, IL.

19 May 2010

USPTO issues Soligenix patent for use of beclomethasone dipropionate in treatment of IBS

Soligenix, Inc., a late-stage biopharmaceutical company, announced today that the United States Patent Office (USPTO) has issued a patent (US 7,704,985) entitled "Treatment of Irritable Bowel Syndrome and Related Bowel Diseases." The patent claims the use of beclomethasone dipropionate (BDP) to treat irritable bowel syndrome (IBS), a painful gastrointestinal condition that affects approximately 15% of the population in the industrialized world.

19 May 2010

Early tracheotomy not beneficial in terms of MV duration, mortality compared to late tracheotomy

Early tracheotomy in ICU patients on mechanical ventilation (MV) did not reduce mortality when compared to later tracheotomy in a study of cardiac surgery patients requiring prolonged ventilation in a Paris study.

19 May 2010

Family plays vital role in children's oral health: General Dentistry

Parents are a child's first teacher in life and play a significant role in maintaining his or her overall health. Providing oral health education to mothers and families is essential to teaching children healthy habits and preventing early childhood tooth decay, according to an article published in the May/June 2010 issue of General Dentistry, the peer-reviewed clinical journal of the Academy of General Dentistry.

18 May 2010

KaloBios Pharmaceuticals' KB001 promising in prevention of serious lung infection

The data from the initial clinical studies with KB001, a novel antibody fragment against PcrV on Pseudomonas aeruginosa (Pa) bioengineered by KaloBios Pharmaceuticals, Inc. and partnered with sanofi pasteur, demonstrated promising therapeutic activity in the prevention of serious lung infection in mechanically ventilated patients colonized with the bacterium and in limiting potentially damaging inflammation in patients with cystic fibrosis, where Pa plays an important role in the disease.

18 May 2010

Article demonstrates single agent activity of KRX-0401 in neuroblastoma tumor preclinical models

Keryx Biopharmaceuticals today announced the publication of an article in the May 12th Journal of the National Cancer Institute, entitled "In Vitro and In Vivo Inhibition of Neuroblastoma Tumor Cell Growth by AKT Inhibitor Perifosine," demonstrating the single agent activity of KRX-0401 (perifosine) in neuroblastoma tumor preclinical models.

18 May 2010

Dental care during pregnancy is essential for combating adverse effects of oral disease

It's no secret that pregnancy is an important time in a woman's life. While women often hear about how pregnancy causes physical changes that affect their hormone or appetite levels, these changes can have a great effect on their oral health as well. Despite the fact that good oral health is essential for the overall health of both mother and child, only 22 to 34 percent of women in the United States visit a dentist during pregnancy.

18 May 2010

Emisphere Technologies first-quarter net loss increases to $18.5 million

Emisphere Technologies, Inc. today announced its financial results for the first quarter 2010.

17 May 2010

Argos Therapeutics presents AGS-004 autologous dendritic cell therapy Phase 2a trial data at 19th CAHR

Argos Therapeutics today announced the presentation of data from the Phase 2a trial of AGS-004, demonstrating that the personalized immunotherapy has a positive impact on the genetic diversity of residual HIV virus, and also results in substantially increased time to viral rebound in HIV patients treated with AGS-004 following antiretroviral therapy (ART) interruption.

17 May 2010

Soligenix first-quarter revenues decrease to $336,000

Soligenix, Inc., a late-stage biopharmaceutical company, announced today its financial results for the first quarter of 2010.

17 May 2010

Novel internet-based strategy effective in patients with severe prednisone dependent asthma

Patients with severe asthma who use an internet-supported strategy and daily monitoring of exhaled nitric oxide were able to control their asthma with lower overall dosing of oral corticosteroids than patients who underwent usual care, according to research from the Netherlands.

17 May 2010

Better health care for the indigenous population

A report from Melbourne University says that Indigenous Australians are six times more likely than other Australians to be blind and more than a third of this population has never had an eye examination. Now a substantial number of optometrists will be sent to remote Aboriginal communities under a $6.5 million federal program.

16 May 2010

Indigenous Australians at higher risk of diseases: studies

Central Australia ranks first in incidences of pneumonia among children with alarming figures like 78.4 cases per 1,000 children annually. This is much higher than even South Africa, Uruguay, Gambia, Fiji or Pakistan.

16 May 2010

Oral News and Research

BIOCIUS and Agilent launch RF360 High Resolution System for high-throughput screening of in vitro ADME assays

New study uses NMR in drug design

Androgen receptors promote hepatitis B virus in growth and development of hepatoma cells

Scientists present data on denufosol tetrasodium for CF at ATS 2010 International Conference

2010 funding program for Inova Life Sciences - George Mason University research collaboration open

Loyola University Chicago introduces new online doctorate degree program in bioethics

FDA grants 510(k) market clearance for EraGen's MultiCode-RTx HSV 1&2 Kit

Results from Phase 1 clinical trials of TRC105, TRC102, and TRC093 to be presented at ASCO 2010

USPTO issues Soligenix patent for use of beclomethasone dipropionate in treatment of IBS

Early tracheotomy not beneficial in terms of MV duration, mortality compared to late tracheotomy

Family plays vital role in children's oral health: General Dentistry

KaloBios Pharmaceuticals' KB001 promising in prevention of serious lung infection

Article demonstrates single agent activity of KRX-0401 in neuroblastoma tumor preclinical models

Dental care during pregnancy is essential for combating adverse effects of oral disease

Emisphere Technologies first-quarter net loss increases to $18.5 million

Argos Therapeutics presents AGS-004 autologous dendritic cell therapy Phase 2a trial data at 19th CAHR

Soligenix first-quarter revenues decrease to $336,000

Novel internet-based strategy effective in patients with severe prednisone dependent asthma

Better health care for the indigenous population

Indigenous Australians at higher risk of diseases: studies

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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