Genome News and Research

RSS

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Findings by scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna reveal a surprising role for histone deacetylase 1 (HDAC1) - a member of a family of chromatin modifying proteins - in the development of skin tumors.

18 Nov 2013

DNA tells the story of how ancient humans first came to the Americas

University of Illinois anthropology professor Ripan Malhi looks to DNA to tell the story of how ancient humans first came to the Americas and what happened to them once they were here.

18 Nov 2013

Close to 100 novel human gene regions that code for proteins may be linked to cancer

By using a new analysis method, researchers at Karolinska Institutet and Science for Life Laboratory (SciLifeLab) in Sweden have found close to one hundred novel human gene regions that code for proteins. A number of these regions are so-called pseudogenes, which may be linked to cancer.

18 Nov 2013

Scientists discover gene associated with high risk of severe childhood asthma.

An international scientific team has discovered a gene associated with a high risk of severe childhood asthma. The specific gene variant may be an actual cause of this form of asthma, a leading cause of hospitalization in young children.

17 Nov 2013

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Researchers at Case Western Reserve University and Cleveland Clinic Lerner Research Institute have discovered recent genetic mutations in a parasite that causes over 100 million cases of malaria annually-changes that may render tens of millions of Africans who had been considered resistant, susceptible to infection.

16 Nov 2013

Researchers explain new function of 2 key molecules involved in tumor progression

Researchers from IMIM (Hospital del Mar Medical Research Institute) lead by Dr. Sandra Peir- have described a new function for two key molecules involved in tumor progression.

16 Nov 2013

Genome sequence data indicates that common species of malaria may evolve to become bigger threat

Provocative new research shows that the Plasmodium vivax parasite, responsible for nearly 20 million cases of malaria in 2010, may be "rapidly evolving" to overcome the natural resistance conferred by a blood type found in millions of Africans, scientists reported today at the annual meeting of the American Society of Tropical Medicine and Hygiene.

16 Nov 2013

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

The Joint Center for Cancer Precision Medicine, a collaborative initiative among Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, and the Broad Institute of MIT and Harvard, has been established to create "precision medicine treatment pathways" for patients with advanced cancers and to speed the development of personalized therapies.

16 Nov 2013

Researchers use new approach to parse roles of key mutated protein that causes familial AD

Researchers at the University of California, San Diego School of Medicine have used genetic engineering of human induced pluripotent stem cells to specifically and precisely parse the roles of a key mutated protein in causing familial Alzheimer's disease, discovering that simple loss-of-function does not contribute to the inherited form of the neurodegenerative disorder.

15 Nov 2013

Taiwan scientists confirm world’s first case of wild avian influenza A H6N1 virus in human

Scientists from Taiwan report on the world’s first confirmed case of human infection with a wild avian influenza A H6N1 virus in The Lancet Respiratory Medicine.

14 Nov 2013

Researchers generate most complete genome sequences from single cells and individual neurons

Researchers led by bioengineers at the University of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. The breakthrough comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.

14 Nov 2013

Research findings call for a rethinking of cancer genetics

Johns Hopkins researchers report that the deletion of any single gene in yeast cells puts pressure on the organism’s genome to compensate, leading to a mutation in another gene. Their discovery, which is likely applicable to human genetics because of the way DNA is conserved across species, could have significant consequences for the way genetic analysis is done in cancer and other areas of research, they say.

14 Nov 2013

Professor receives NOK 75M grant to develop idea for next generation personalized cancer therapy

Extensive statistical analyses of the mutation distribution in several thousand cancerous tumours make it possible to find cures for types of cancer that cannot be treated today.

13 Nov 2013

Study uncovers novel mechanism that helps govern regulated gene expression

A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression. The study was published on line in advance of print November 10 in the journal Nature Structural and Molecular Biology.

13 Nov 2013

Agilent collaborates with Baylor College of Medicine to provide CGH microarrays to researchers

Agilent Technologies Inc. has announced it is collaborating with Baylor College of Medicine's Medical Genetics Laboratories to provide customized CGH (comparative genomics hybridization) microarrays to researchers worldwide. Six new microarray designs unite the power of Baylor's data-rich expertise in genetics research with Agilent's microarray manufacturing capabilities to enable advanced discoveries in cancer and cytogenetics research.

12 Nov 2013

Viewpoints: Shinseki's efforts haven't yet solved VA's problems; treating children with mental illness is complicated; abuse of painkillers

Just in time for Veterans Day, the embattled secretary of Veterans Affairs, Eric K. Shinseki, announced last week that his department had reduced its backlog of overdue disability claims from more than 600,000 in March to about 400,000. "The trend line is in the right direction," Shinseki told reporters, noting that the VA had cut the number of claims older than a year by 93%. With hundreds of thousands of cases still unresolved, Shinseki hasn't gotten much credit so far - but to the surprise of his critics, he's on track to achieve his goal of eliminating the backlog by 2015. Still, that won't solve all the VA's problems; far from it (Doyle McManus, 11/10).

12 Nov 2013

Scientists use new technology to study whole genome to find the cause of genetic disease

For the first time, scientists have used new technology which analyses the whole genome to find the cause of a genetic disease in what was previously referred to as "junk DNA".

11 Nov 2013

A*STAR scientists discover potential target to weed out progression of cancer

Scientists at A*STAR have discovered an enzyme, Wip1 phosphatase, as a potential target to weed out the progression of cancer. Although studies in the past have revealed that this enzyme plays a critical role in regulating the budding of tumours, scientists have for the first time unearthed a mechanism for its mode of action.

10 Nov 2013

Coding variants in immune disease-related genes play only small part in risk for psoriasis

Coding variants in immune disease-related genes play only a small part in the overall genetic risk for psoriasis, according to a new study led by Anhui Medical University and BGI.

10 Nov 2013

Cancer research leaders announce the opening of ICGC-TCGA-DREAM SMC Challenge

Cancer research leaders from the Ontario Institute for Cancer Research and the University of California, Santa Cruz, in collaboration with Sage Bionetworks and IBM's DREAM, will announce tomorrow the opening of the ICGC-TCGA-DREAM Somatic Mutation Calling Challenge at the Sixth Annual RECOMB/ISCB conference.

8 Nov 2013

Genome News and Research

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

DNA tells the story of how ancient humans first came to the Americas

Close to 100 novel human gene regions that code for proteins may be linked to cancer

Scientists discover gene associated with high risk of severe childhood asthma.

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Researchers explain new function of 2 key molecules involved in tumor progression

Genome sequence data indicates that common species of malaria may evolve to become bigger threat

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

Researchers use new approach to parse roles of key mutated protein that causes familial AD

Taiwan scientists confirm world’s first case of wild avian influenza A H6N1 virus in human

Researchers generate most complete genome sequences from single cells and individual neurons

Research findings call for a rethinking of cancer genetics

Professor receives NOK 75M grant to develop idea for next generation personalized cancer therapy

Study uncovers novel mechanism that helps govern regulated gene expression

Agilent collaborates with Baylor College of Medicine to provide CGH microarrays to researchers

Viewpoints: Shinseki's efforts haven't yet solved VA's problems; treating children with mental illness is complicated; abuse of painkillers

Scientists use new technology to study whole genome to find the cause of genetic disease

A*STAR scientists discover potential target to weed out progression of cancer

Coding variants in immune disease-related genes play only small part in risk for psoriasis

Cancer research leaders announce the opening of ICGC-TCGA-DREAM SMC Challenge

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News