Inflammation News and Research

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Researchers find a class of drug that could be promising treatment for uveitis

Ocular inflammation uveitis is a serious disease that can destroy eye tissue and cause irreversible blindness.

2 Nov 2018

Researchers take first step in bioengineering human uterus to treat endometrial diseases

Researchers at Northwestern Medicine have taken the first step in bioengineering the human uterus to treat endometriosis, uterine-factor infertility and endometrial cancer.

1 Nov 2018

Inflammation can cause sleep and shiftwork-type disorders

Inflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome and Crohn's disease, has unexpected effects on body clock function and can lead to sleep and shiftwork-type disorders, a new Northwestern Medicine study in mice found.

31 Oct 2018

Study offers hope of early detection, treatment of liver cancer

Liver cancer is the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. Most cases are discovered too late for a cure -- but now a study offers hope of early detection, and targets for new treatments.

31 Oct 2018

Alzheimer's Association's Part the Cloud program funds innovative research on brain cells

Innovative research aimed to possibly rejuvenate brain cells will be explored by six international researchers with the goal of discovering effective drugs for people with early stage Alzheimer's disease and other dementias.

31 Oct 2018

UA pharmacology professors aim to avoid opioid analgesic tolerance

For thousands of Americans, opioids no longer relieve pain -- they cause pain. Known as "opioid tolerance," patients eventually become desensitized to opioids and more sensitive to pain after years of using the pain relievers.

31 Oct 2018

Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Delivering an effective therapeutic payload to specific target cells with few adverse effects is considered by many to be the holy grail of medical research. A new Tel Aviv University study explores a biological approach to directing nanocarriers loaded with protein "game changers" to specific cells.

30 Oct 2018

Atopic dermatitis found to be highly prevalent among adults in the U.S.

As many as 16.5 million adults in America suffer from a skin disease known as atopic dermatitis, an inflammatory disease that results in red, itchy skin.

30 Oct 2018

New findings highlight importance of inflammatory component in atherosclerosis pathogenesis

One of the main characteristics of atherosclerosis is the accumulation of lipids in the intimal layer of the arterial wall.

29 Oct 2018

Common diabetes medication may protect against age-related macular degeneration

Researchers from Taiwan have shown that people with type 2 diabetes who took a common diabetes medication, metformin, had a significantly lower rate of age-related macular degeneration.

29 Oct 2018

Novartis enters into clinical development agreement with Pfizer to improve treatment of NASH

Novartis announced today that it has entered into a clinical development agreement with Pfizer which will include a study combining tropifexor and one or more Pfizer compounds for the treatment of NASH, including an Acetyl CoA-Carboxylase (ACC) Inhibitor (PF-05221304, a Diacylglycerol O-Acyltransferase 2 (DGAT2) Inhibitor (PF-06865571, and a Ketohexokinase (KHK) Inhibitor (PF-06835919).

29 Oct 2018

Toxic effects of drugs in the lungs 'more widespread than thought'

A systematic review of research has revealed that the toxic effects on the lung of drugs commonly taken to treat a range of common conditions is much more widespread than thought.

29 Oct 2018

Getting right level of leptin may help protect cardiovascular health

Like that famous bowl of porridge, when leptin levels are "just right" they help protect our cardiovascular health, scientists say.

29 Oct 2018

Researchers identify new potential target to inhibit progression of liver disease

Naglaa Shoukry, Ph. D., and her team have made a significant breakthrough in their research aiming to limit the progression of liver disease.

26 Oct 2018

Tel Aviv University researchers uncover biological ultraviolet protection 'timer'

Scientists at Tel Aviv University have discovered a critical 48-hour cycle that is responsible for synchronizing the biological mechanisms that protect our skin from sun damage.

26 Oct 2018

New method to block immunosuppression in cancer discovered

Belgian research groups from the UCLouvain and WELBIO, VIB and Ghent University, and the biotechnology company argenx elucidated the three-dimensional structure of an assembly of proteins operating on cells that dampen immune responses

26 Oct 2018

Treating gum disease could help people with Type 2 diabetes manage their blood glucose levels

A study funded by Diabetes UK has found that treating periodontitis (gum disease) could help people with Type 2 diabetes manage their blood glucose levels, and may reduce their risk of diabetes-related complications.

25 Oct 2018

Researchers discover mechanisms that lead to osteoarthritis after knee joint injury

Knee joint injuries are typically related to sports, such as football, rugby or ice hockey, but people often do not know that such injuries may lead to joint inflammation and post-traumatic osteoarthritis.

25 Oct 2018

Researchers track where tetracycline antibiotics go in human cells

We know that antibiotics treat bacterial infections. We also know why they work. Tetracycline antibiotics, for example, stop bacteria from making protein. Like a boot on a wheel, the drugs bind to the bacterial cell's ribosome--where protein is made--and prevent it from working. Without protein, the bacteria weaken and die.

25 Oct 2018

Targeting specific signaling pathway could provide new avenue for treating fetal alcohol syndrome

Fetal alcohol spectrum disorders are an array of conditions that can occur in a person whose mother consumed alcohol during pregnancy. Fetal alcohol syndrome, the most severe of these conditions, often results in physical abnormalities, behavioral development issues and intellectual disabilities.

24 Oct 2018

Inflammation News and Research

Researchers find a class of drug that could be promising treatment for uveitis

Researchers take first step in bioengineering human uterus to treat endometrial diseases

Inflammation can cause sleep and shiftwork-type disorders

Study offers hope of early detection, treatment of liver cancer

Alzheimer's Association's Part the Cloud program funds innovative research on brain cells

UA pharmacology professors aim to avoid opioid analgesic tolerance

Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Atopic dermatitis found to be highly prevalent among adults in the U.S.

New findings highlight importance of inflammatory component in atherosclerosis pathogenesis

Common diabetes medication may protect against age-related macular degeneration

Novartis enters into clinical development agreement with Pfizer to improve treatment of NASH

Toxic effects of drugs in the lungs 'more widespread than thought'

Getting right level of leptin may help protect cardiovascular health

Researchers identify new potential target to inhibit progression of liver disease

Tel Aviv University researchers uncover biological ultraviolet protection 'timer'

New method to block immunosuppression in cancer discovered

Treating gum disease could help people with Type 2 diabetes manage their blood glucose levels

Researchers discover mechanisms that lead to osteoarthritis after knee joint injury

Researchers track where tetracycline antibiotics go in human cells

Targeting specific signaling pathway could provide new avenue for treating fetal alcohol syndrome

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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