Immune System News and Research

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Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal that the bone marrow niche where HSC's form also ages, contributing to the problem.

3 Mar 2017

Sex differences in microglia activity affect pain treatment, study finds

A female brain's resident immune cells are more active in regions involved in pain processing relative to males, according to a recent study by Georgia State University researchers.

2 Mar 2017

Researcher examines scarring process in hope of preventing chronic lung transplant rejection

For patients affected by lung diseases such as pulmonary fibrosis, chronic obstructive pulmonary disease, cystic fibrosis and others, cures for their diseases are incredibly rare, if not nonexistent.

2 Mar 2017

Scientists track 'guardian immune cells' to uncover mechanics underlying inflammation and obesity

Scientists have uncovered the physiological mechanics underlying inflammation and obesity by tracking the actions of 'guardian immune cells' in response to changes in diet.

2 Mar 2017

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Using antibodies to treat disease has been one of the great success stories of early 21st-century medicine. Already five of the ten top-selling pharmaceuticals in the United States are antibody products. But antibodies are large, complex proteins that can be expensive to manufacture.

2 Mar 2017

Study increases understanding of how air pollution affects human health

Researchers from the University of Leicester have for the first time discovered that bacteria that cause respiratory infections are directly affected by air pollution - increasing the potential for infection and changing the effectiveness of antibiotic treatment.

2 Mar 2017

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

A Japanese research group has discovered that a newly-identified autoimmune endocrine disease that leads to hypopituitarism is caused by thymomas (a type of tumor originating from the thymic gland).

2 Mar 2017

Probiotic combination may help reduce hay fever symptoms, research shows

As we head into allergy season, you may feel less likely to grab a hanky and sneeze. That's because new University of Florida Institute of Food and Agricultural Sciences research shows a probiotic combination might help reduce hay fever symptoms, if it's taken during allergy season.

2 Mar 2017

Immune-stimulating chemical found in tumors may help stop cancer growth

A chemical found in tumors may help stop tumor growth, according to a new study.

2 Mar 2017

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers at Monash University and Peter MacCallum Cancer Centre have identified for the first time how a new class of epigenetic drug engages with the immune system to kill off cancer cells, offering powerful new pathways for enhanced blood cancer therapies.

1 Mar 2017

Immune system defect makes Addison’s patients prone to respiratory infections

Research led by University of Birmingham scientists has found that people suffering from the adrenal disorder known as Addison's disease suffer from an immune system defect which makes them prone to potentially deadly respiratory infections.

1 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

University of North Carolina Lineberger Comprehensive Cancer Center researchers have achieved a major milestone with the launch of two clinical trials testing an experimental therapy in which patients' own immune cells are genetically engineered to fight their cancer.

1 Mar 2017

Novel NMR spectroscopy platform holds potential to revolutionize drug development practices

Implementation of a new nuclear magnetic resonance spectroscopy platform will provide professors Nicolas Doucet and Steven LaPlante of Centre INRS-Institut Armand-Frappier with a powerful new tool for conducting an ambitious research program aimed at identifying new therapeutic molecules.

28 Feb 2017

Genetic variation may be reason for overreaction of immune system to viruses

Researchers at Cardiff University have discovered that genetic variation is the reason why some immune systems overreact to viruses.

28 Feb 2017

Activated T-cells promote heart failure after heart attack

Chronic inflammation after a heart attack can promote heart failure and death. University of Alabama at Birmingham researchers have now shown that activated T-cells — part of the immune system's inflammatory response — are both necessary and sufficient to produce such heart failure.

28 Feb 2017

Researchers justify alternative theory about cause of type 1 diabetes

An international team of researchers led by City of Hope's Bart Roep, Ph.D., the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and professor/founding chair of the Department of Diabetes Immunology, has been able to justify an alternative theory about the cause of type 1 diabetes (T1D) through experimental work.

28 Feb 2017

Immune System News and Research

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

Sex differences in microglia activity affect pain treatment, study finds

Researcher examines scarring process in hope of preventing chronic lung transplant rejection

Scientists track 'guardian immune cells' to uncover mechanics underlying inflammation and obesity

Scientists reveal new mRNA method to deliver safe, cost-effective therapeutic antibodies

Study increases understanding of how air pollution affects human health

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

Probiotic combination may help reduce hay fever symptoms, research shows

Immune-stimulating chemical found in tumors may help stop cancer growth

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Immune system defect makes Addison’s patients prone to respiratory infections

Using Spherical Nucleic Acids to Track and Treat Disease

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

Novel NMR spectroscopy platform holds potential to revolutionize drug development practices

Genetic variation may be reason for overreaction of immune system to viruses

Activated T-cells promote heart failure after heart attack

Researchers justify alternative theory about cause of type 1 diabetes

SBP researchers identify new regulator of innate immune response to foreign invaders

Scientists reveal how gluten plays role in development of rare form of cancer for coeliac patients

Fat stem cells may be preferred type for use in therapeutic applications, study shows

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