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A counter to counterfeit drugs

The counterfeiting of medicines has been known of since around 1990 and is a growing problem-in both developing and developed countries. Counterfeit medicines are estimated as more than 10% of the global medicines market and in some developing countries it is thought to be as high as 50%. One prediction is that global counterfeit drug sales will reach $75 billion by 2010.

30 Jul 2008

New insights into the neural circuitry of trust

The brain centers triggered by a betrayal of trust have been identified by researchers, who found they could suppress such triggering and maintain trust by administering the brain chemical oxytocin. The researchers said their findings not only offer basic insights into the neural machinery underlying trust; the results may also help in understanding the neural basis of social disorders such as phobias and autism.

21 May 2008

First 3-D view of anti-cancer agent

Researchers from the Indiana University School of Medicine and the Purdue School of Science at Indiana University-Purdue University Indianapolis have created the first three-dimensional image of how a well-established chemotherapy agent targets and binds to DNA.

19 Mar 2008

Purdue tackles large public health issue at indoor swimming pools

Researchers at Purdue University have determined how certain airborne contaminants are created when chlorine reacts with sweat and urine in indoor swimming pools, a step toward learning how to reduce the formation of "volatile disinfection byproducts" that cause respiratory irritation.

20 Feb 2008

Scientists solve structure of gene regulator that plays key role in cancer

Scientists at The Wistar Institute have collaborated on a major advance in understanding a gene regulator that contributes to some of the deadliest cancers in humans.

14 Feb 2008

Researchers pinpoint brain region responsible for pain's ability to affect cognitive processing

Anybody who's tried to concentrate on work while suffering a headache knows that pain compellingly commands attention,which is how evolution helped ensure survival in a painful world.

9 Jul 2007

Researchers catch moving proteins in mid-fold

Any photographer can vouch for the difficulty of capturing a clear picture of a moving target.

17 May 2007

New understanding of cholera pathogen

Researchers at Rensselaer Polytechnic Institute have discovered new details about how bacteria generate energy to live. In two recently published papers, the scientists add key specifics to the molecular mechanism behind the pathogen that causes cholera.

29 Jan 2007

Usefulness of BMI is suspect

For years doctors have used the body mass index (BMI), a ratio of height and weight, to characterize the clinical weight status of their patients.

24 Jul 2006

Functional imaging of numerical processing in adults and 4-y-old children

Four-year-olds who are still developing numerical abilities show activity in the same brain region during numerical tasks as do math-adept adults, Duke University researchers Jessica Cantlon, Kevin Pelphrey and colleagues report in the open access journal PLoS Biology.

11 Apr 2006

Patterns of fMRI activity dissociate overlapping functional brain areas that respond to biological motion

A swaying tree and a moving person activate distinctive areas of the brain's visual cortex, since recognizing people is essential for social interaction. So, an important question in exploring the visual system is how the visual cortex manages such specific recognition of "biological motion."

19 Mar 2006

Research reveals possible mechanisms for the treatment of cocaine addiction

Researchers are now understanding in greater detail the molecular machinery underlying the short-term brain changes that produce the high of cocaine, as well as the longer-term changes behind addiction. Their findings offer hope for targeted drugs that can short-circuit that addiction machinery.

19 Oct 2005

So you thought that smell was cheese!

Researchers in the UK have found that visual words can influence the perception of smells, with pleasant words influencing olfactory brain regions to perceive an odour as pleasant, an interesting idea that might hold particular relevance for restaurateurs and advertisers.

20 May 2005

Researchers make gains in understanding antibiotic resistance

Howard Hughes Medical Institute researchers chiseling away at the problem of antibiotic resistance now have a detailed explanation of how the drugs' main cellular target in bacteria evolves to become resistant to some of these medications.

22 Apr 2005

Faster, more accurate diagnostic test for Sjogren's syndrome

Researchers in Japan are developing a faster, more accurate diagnostic test for Sjögren’s (SHOW-grins) syndrome, an incurable autoimmune disorder characterized by chronically dry eyes and dry mouth.

11 Apr 2005

New ideas for creating a new generation of oral medications to treat infertility

Researchers now have a much better picture of how follicle-stimulating hormone (FSH), one of the most frequently used fertility drugs, works, and with it new ideas for creating a new generation of oral medications to treat infertility.

20 Jan 2005

Findings could lead to new knowledge that could speed the development of drugs to block botulism or tetanus toxins more rapidly

The first detailed structure of a botulism toxin attached to its target protein reveals that the toxin snakes the protein around itself — a sort of “reverse anaconda” — to recognize the receptor.

13 Dec 2004

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Using hairlike microelectrodes and computer analysis, neurobiologists at Duke University Medical Center have demonstrated that they can see the detailed instant-to-instant electrical "brainscape" of neural activity across a living brain.

8 Dec 2004

Spitting into a cup could someday be an alternative to blood testing

Researchers have identified the largest number of proteins to date in human saliva, a preliminary finding that could pave the way for more diagnostic tests based on saliva samples. Such tests show promise as a faster, cheaper and potentially safer diagnostic method than blood sampling, they say.

5 Oct 2004