Cytotoxicity News and Research

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Magnolia essential oil fights bacteria and oxidative stress with natural potency

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17 Apr 2025

Selective depletion of PD-1 positive lymphocytes using a novel bispecific killer engager

This new article publication from Acta Pharmaceutica Sinica B, discusses a bispecific killer engager for targeted depletion of PD-1 positive lymphocytes.

14 Apr 2025

Researchers explore drug repurposing strategy for Parkinson's disease

Despite significant advances in Parkinson's disease (PD) treatment, it remains incurable, with limited therapeutic options.

10 Apr 2025

ICRAFT platform identifies new targets for cancer immunotherapy

Professor Zeng Zexian's team from the Center for Quantitative Biology at the Peking University Academy for Advanced Interdisciplinary Studies, in collaboration with the Peking University-Tsinghua University Joint Center for Life Sciences, has developed ICRAFT, an innovative computational platform for identifying cancer immunotherapy targets.

1 Apr 2025

Traditional Chinese medicine targets cholesterol metabolism for cancer treatment

Researchers explore how natural compounds in traditional Chinese medicine can modulate cholesterol metabolism to combat cancer.

31 Mar 2025

Inhibition of tumor xenograft growth in mice without systemic toxicity

The management of breast cancer involves various therapeutic approaches. However, many current anticancer treatments indiscriminately damage both cancerous and healthy cells. In cancer treatment, Streptomycetes have already been proven as the main resources producing anti-cancer drugs. Streptomyces coelicolor is a representative of the genus Streptomyces.

27 Mar 2025

Anti-HIV active diterpenoids identified in Daphne pseudomezereum

A research group led by Professor Wei Li from the Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Toho University, in collaboration with the Duke University Medical Center in the United States, has discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).

21 Mar 2025

Research poses a new explanation for how cancer-fighting drugs attack and destroy tumor cells

Research by UMass Chan Medical School scientists Sharon Cantor, PhD, and Jenna M. Whalen, PhD, poses a new explanation for how cancer-fighting drugs attack and destroy BRCA1 and BRCA2 tumor cells.

7 Mar 2025

Biomass smoke compounds linked to lung damage and respiratory diseases

Biomass burning-whether from wildfires, wood stoves or agricultural fires-sends massive amounts of tiny particles and chemicals into the air.

27 Feb 2025

Study identifies vitamin E succinate as key to tumor growth control

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to immunotherapy.

12 Feb 2025

Microplastics in food packaging may increase heart disease risk

Microplastics pose a threat to heart health, causing harmful changes in vascular cells and increasing the risk of cardiovascular diseases like atherosclerosis.

10 Feb 2025

Neoantigen vaccine sparks powerful immune defense against kidney cancer

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to long-lasting T cell expansion and no disease recurrence after 40 months.

6 Feb 2025

Researchers develop T cell growth method that enhances cancer-fighting ability in melanoma model

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

31 Jan 2025

Decades of research push cytomegalovirus vaccine closer to reality

Researchers review decades of progress in human cytomegalovirus (HCMV) vaccine development, emphasizing challenges, innovative platforms, and the critical need for effective prevention strategies.

6 Jan 2025

New artificial muscle mimics natural tissue with high elasticity and toughness

The study, led by Dr. Cheng-Hui Li from the School of Chemistry and Chemical Engineering, Nanjing University, and Dr. Pengfei Zheng from the Children's Hospital of Nanjing Medical University, successfully developed an artificial muscle with mechanical properties similar to natural muscle tissue.

2 Jan 2025

Insights into LKB1's role in tumorigenesis

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101402, discusses insights into targeting LKB1 in tumorigenesis.

20 Dec 2024

Exploring the cytotoxic potential of neocryptolepine derivatives against cancer

Announcing a new publication for Acta Materia Medica journal. Cancer has been a severe public health and social problem, a leading disease that has diminished the quality of life, and a barrier to improving life expectancy.

13 Dec 2024

Ketone body β-hydroxybutyrate restores protein balance and targets Alzheimer’s-linked aggregates

Scientists identify β-hydroxybutyrate as a key regulator of protein solubility, offering a novel pathway to combat neurodegeneration in aging and Alzheimer’s disease.

4 Dec 2024

Cancer therapy may raise heart attack and stroke risks by disrupting immune regulation in arteries

Immune checkpoint inhibitors may heighten cardiovascular risks by altering immune interactions in atherosclerotic plaques, particularly in diabetic patients.