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New molecule shows promise in treating acetaminophen-induced liver injury

Acetaminophen is one of the most common painkillers and is found in hundreds of different medications. While safe at recommended doses, acetaminophen overdose is the leading cause of acute liver injury in the U.S.

18 Aug 2025

Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds

A large Medicare cohort study found that older adults prescribed pregabalin had a significantly higher risk of developing heart failure compared to those prescribed gabapentin. The elevated risk was most pronounced in individuals with pre-existing cardiovascular disease, especially women and White patients.

13 Aug 2025

Understanding opioid safety and overdose prevention for older adults

With increasing age, older adults are more likely to encounter health conditions and injuries that require opioid therapy for pain relief.

13 Aug 2025

Cherokee Nation Behavioral Health and Emory team up to prevent youth substance use

While overdose deaths in the U.S. sharply declined in 2024, they remain high. Almost 90,000 Americans died from drug overdoses between October 2023 and September 2024.

6 Aug 2025

As California’s behavioral health workforce buckles, help is years away

This spring, the Good News Rescue Mission, which runs the only emergency homeless shelter in Shasta County, received a game-changing $17.8 million state grant to build a 75-bed residential treatment facility in a region where thousands struggle with drug and alcohol addiction.

6 Aug 2025

New analgesic shows promise as opioid alternative

Opioids like morphine are widely used in medical practice due to their powerful pain-relieving effects. However, they carry the risk of serious adverse effects such as respiratory depression and drug dependence.

4 Aug 2025

Deadly opioid contaminants uncovered in Adelaide street drug supply

A synthetic opioid 1000 times more potent than morphine is infiltrating the street drug trade in Adelaide, Australia, sparking fears of a wave of overdoses that could be lethal.

1 Aug 2025

Copper may protect brain health after stroke

Research shows dietary copper intake boosts cognitive function in older adults, particularly those with a stroke history, highlighting its neuroprotective role.

1 Aug 2025

ANXA2 positive hepatocytes drive migration based repair in acute liver failure

Acute liver failure (ALF) represents a life-threatening condition marked by rapid deterioration of liver function, often necessitating urgent liver transplantation.

18 Jul 2025

New funding empowers Be Well Texas to combat opioid crisis

The Texas Health and Human Services Commission has selected Be Well Texas, an initiative of the Be Well Institute on Substance Use and Related Disorders at The University of Texas Health Science Center at San Antonio (UT Health San Antonio), to lead a major expansion of opioid use disorder and recovery support services across Texas.

17 Jul 2025

Exploring the changing intensity of opioid use

Illegal opioids can create substantial harms, but the extent of those harms depends on multiple factors, including the amount consumed.

16 Jul 2025

Nearly one-third of UK maternal deaths tied to involvement of children's social care services

The involvement of children's social care services was a common factor in nearly a third of UK maternal deaths occurring during, or within a year of, pregnancy between 2014 and 2022, finds research published in the open access journal BMJ Medicine.

12 Jul 2025

Who’s policing opioid settlement spending? A crowdsourced database might help

After years of legal battles, state attorneys general won billions of dollars in opioid settlements from drug companies accused of fueling the addiction crisis. They declared victory at press conferences, and some touted the deals during their gubernatorial campaigns.

11 Jul 2025

In a nation growing hostile toward drugs and homelessness, Los Angeles tries leniency

Inside a bright new building in the heart of Skid Row, homeless people hung out in a canopy-covered courtyard — some waiting to take a shower, do laundry, or get medication for addiction treatment.

8 Jul 2025

Most Medicaid plans cover naloxone but barriers still exist

A new study found that almost all plans in 40 states and Washington, DC covered at least one form of the opioid overdose reversal drug naloxone, although certain restrictions and quantity limits may still prevent people from accessing this life-saving drug.

27 Jun 2025

New toolkit aims to transform opioid education through patient collaboration

It's difficult to overstate the corrosive impact of Canada's ongoing opioid crisis. Since 2016, there have been over 40,000 opioid-related deaths across the country, devastating Canadian families from all walks of life. Opioid-related hospitalizations and calls to paramedics have ballooned.

20 Jun 2025

Cardiovascular deaths surge among less educated Americans

About 525,000 more deaths occurred among US adults in 2023 than would be expected had pre-2010 mortality trends continued. More than 90 percent of these deaths occurred among individuals without a Bachelor's degree and were largely caused by cardiovascular diseases, underscoring how educational attainment can influence individuals' health opportunities and outcomes.

14 Jun 2025

Green light activates modified penicillin to target bacterial infections

To treat bacterial infections, medical professionals prescribe antibiotics. But not all active medicine gets used up by the body.

12 Jun 2025

Mount Sinai receives NIH grant to study overdoses linked to synthetic opioids

The Icahn School of Medicine at Mount Sinai has been awarded a $3.8 million grant from the National Institute on Drug Abuse, a division of the National Institutes of Health, to study drug overdose cases linked to novel synthetic opioids.

10 Jun 2025

Two patients faced chemo. The one who survived demanded a test to see if it was safe.

JoEllen Zembruski-Ruple, while in the care of New York City's renowned Memorial Sloan Kettering Cancer Center, swallowed the first three chemotherapy pills to treat her squamous cell carcinoma on Jan. 29, her family members said. They didn't realize the drug could kill her.

4 Jun 2025