Plasmodium falciparum News and Research

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Researchers identify key role of enzyme essential for invasion of the toxoplasmosis parasite

Scientists from the universities of Geneva and Zurich and the PSI have identified the structure and functions of RON13, an enzyme of the toxoplasmosis parasite that is essential for the infectious mechanism in humans.

24 Jun 2021

Novel vaccine based on mRNA technology protects against malaria in animal models

Scientists from the Walter Reed Army Institute of Research and Naval Medical Research Center partnered with researchers at the University of Pennsylvania and Acuitas Therapeutics to develop a novel vaccine based on mRNA technology that protects against malaria in animal models, publishing their findings in npj Vaccines.

18 Jun 2021

Malaria parasites may survive, replicate within the spleen of asymptomatic individuals, study suggests

Malaria, a disease caused mainly by the parasites Plasmodium falciparum and Plasmodium vivax, (P. vivax) is associated with over 400,000 deaths each year.

1 Jun 2021

Researchers map malaria parasites in unprecedented cellular detail

Researchers have mapped in fine detail the genetic changes malaria parasites go through as they prepare to infect people.

28 May 2021

Researchers reach new milestone in the development of effective malaria vaccine

Sanaria PfSPZ-CVac" is a live vaccine consisting of infectious Plasmodium falciparum (Pf) malaria parasites that are injected into the subject at the same time as they receive an antimalarial drug.

5 May 2021

World Malaria Day 2021: An interview with Sir Brian Greenwood

News-Medical interviews Sir Brian Greenwood about raising awareness for malaria during the COVID-19 pandemic and achieving elimination of the disease.

23 Apr 2021

Malaria mutations may be gaining a foothold in Africa, shows new data

New data provide the first clinical evidence that drug-resistant mutations in the malaria parasite Plasmodium falciparum may be gaining a foothold in Africa.

15 Apr 2021

Study finds remarkable differences in the way individuals respond to malaria

Scientists have discovered that tracking malaria as it develops in humans is a powerful way to detect how the malaria parasite causes a range of infection outcomes in its host.

31 Mar 2021

Deforestation may cause initial increase in malaria infections across Southeast Asia

Deforestation may cause an initial increase in malaria infections across Southeast Asia before leading to later decreases, a study published today in eLife suggests.

10 Mar 2021

Basigin does not facilitate SARS-CoV-2 entry, say researchers

Researchers investigated the significance of a transmembrane glycoprotein basigin, or CD147, as a host cell co-receptor required for the entry of SARS-CoV-2. The findings reveal that recombinant human basigin does not interact with full-length spike protein or spike RBD of SARS-CoV-2.

24 Feb 2021

World's largest resource of genome variation data on malaria parasites released

Genome variation data on more than 7,000 malaria parasites from 28 endemic countries is released today (24 February) in Wellcome Open Research.

24 Feb 2021

Countries with older populations have higher SARS-CoV-2 infections and deaths, says study

A new study examines some patterns revealed by a study of the factors operating in different regions and countries, to offer plausible hypotheses of these variations.

23 Feb 2021

Cone snail venom could potentially treat severe forms of malaria

Severe forms of malaria such as Plasmodium falciparum may be deadly even after treatment with current parasite-killing drugs.

18 Feb 2021

Development of malaria vaccines deserves urgent attention just like COVID-19

Developing vaccines to fight malaria deserves urgent attention just like COVID-19, argues Damaris Matoke-Muhia.

17 Feb 2021

New findings could help better understand the mechanisms underlying severe malaria

The levels of small molecules called microRNAs (miRNAs) circulating in blood could help identify early on children with life-threatening forms of malaria, according to a study led by the Barcelona Institute for Global Health, an institution supported by "la Caixa" Foundation, in collaboration with the Manhiça Health Research Center (CISM) in Mozambique.

13 Jan 2021

Multiple blood feeding by mosquitoes may increase malaria transmission

Multiple bouts of blood feeding by mosquitoes shorten the incubation period for malaria parasites and increase malaria transmission potential, according to a study published December 31 in the open-access journal PLOS Pathogens by Lauren Childs of Virginia Tech, Flaminia Catteruccia of the Harvard T.H. Chan School of Public Health, and colleagues.

4 Jan 2021

Population mobility patterns could help address malaria in the Amazon, say scientists

Understanding population mobility patterns could hold the key to tackling malaria in the Amazon, say scientists. Malaria has traditionally been seen as a rural scourge, but increasingly it is being documented in or near urban areas, experts warn, as a new study shows that human mobility plays an important role in the "urbanization" of the disease.

17 Dec 2020

School children with no malaria symptoms could be super-spreaders of the disease

School-age children with no malaria symptoms could serve as super-spreaders of the disease, an observation that could open a new chapter on malaria control, a meeting has heard. The new findings from a study that was conducted in Uganda were reported at the virtual annual meeting of the American Society of Tropical Medicine and Hygiene last month (18 November).

3 Dec 2020

Lancaster University to help control the spread of invasive malaria mosquito

Lancaster University is involved in a major research project which aims to control the spread of an invasive malaria mosquito in Sudan and Ethiopia.

20 Nov 2020

Royal Government of Cambodia commits to eliminating the deadliest strain of malaria

The Royal Government of Cambodia (RGC) today committed to eliminating Plasmodium falciparum within the next few months, and to maintaining zero cases by 2023, through the launch of an innovative and targeted approach for the ‘last mile’ of malaria elimination in the country.

16 Nov 2020