Restless Legs Syndrome News and Research

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Restless legs syndrome (RLS) is a neurological disorder characterized by unpleasant sensations in the legs and an uncontrollable urge to move when at rest in an effort to relieve these feelings. RLS sensations are often described by people as burning, creeping, tugging, or like insects crawling inside the legs. Often called paresthesias (abnormal sensations) or dysesthesias (unpleasant abnormal sensations), the sensations range in severity from uncomfortable to irritating to painful.

The most distinctive or unusual aspect of the condition is that lying down and trying to relax activates the symptoms. As a result, most people with RLS have difficulty falling asleep and staying asleep. Left untreated, the condition causes exhaustion and daytime fatigue. Many people with RLS report that their job, personal relations, and activities of daily living are strongly affected as a result of their exhaustion. They are often unable to concentrate, have impaired memory, or fail to accomplish daily tasks.
XenoPort to present arbaclofen placarbil, XP13512 trial data at 62nd American Academy of Neurology meeting

XenoPort to present arbaclofen placarbil, XP13512 trial data at 62nd American Academy of Neurology meeting

FDA approves Mirapex ER tablets for signs and symptoms of idiopathic PD

FDA approves Mirapex ER tablets for signs and symptoms of idiopathic PD

Rapidly declining memory in people with cognitive impairment may indicate stage before Alzheimer's disease

Rapidly declining memory in people with cognitive impairment may indicate stage before Alzheimer's disease

Sleep deprivation may increase heart attack risk

Sleep deprivation may increase heart attack risk

People with varicose veins should seek professional consultation

People with varicose veins should seek professional consultation

Omeros obtains exclusive license to compounds from Asubio Pharma for use in its PDE7 program

Omeros obtains exclusive license to compounds from Asubio Pharma for use in its PDE7 program

Positive interim results from NxStage Medical's FREEDOM study in RLS

Positive interim results from NxStage Medical's FREEDOM study in RLS

Varicose veins may signal potential dangerous blood clots

Varicose veins may signal potential dangerous blood clots

Clot-busting drug therapy after stroke beneficial for women

Clot-busting drug therapy after stroke beneficial for women

Boehringer Ingelheim Pharmaceuticals receives FDA approval for Mirapex ER in treatment of early PD

Boehringer Ingelheim Pharmaceuticals receives FDA approval for Mirapex ER in treatment of early PD

Depomed receives final meeting minutes from FDA for pre-NDA meeting on DM-1796 for PHN

Depomed receives final meeting minutes from FDA for pre-NDA meeting on DM-1796 for PHN

FDA issues Complete Response Letter for Horizant in treatment of RLS

FDA issues Complete Response Letter for Horizant in treatment of RLS

Research findings highlight the vital need for better secondary stroke prevention

Research findings highlight the vital need for better secondary stroke prevention

Memory loss or decline in thinking abilities may indicate higher risk of stroke

Memory loss or decline in thinking abilities may indicate higher risk of stroke

Reducing DA dosage causes acute withdrawal symptoms in Parkinson's patients

Reducing DA dosage causes acute withdrawal symptoms in Parkinson's patients

Erectile dysfunction linked to RLS in older men

Erectile dysfunction linked to RLS in older men

Study: Men who do moderate-to-heavy intensity exercise are less likely to have stroke

Study: Men who do moderate-to-heavy intensity exercise are less likely to have stroke

Astellas Pharma and XenoPort submit NDA in Japan for PMDA approval

Astellas Pharma and XenoPort submit NDA in Japan for PMDA approval

Children with autism may have lower quality handwriting, says study

Children with autism may have lower quality handwriting, says study

FDA extends review date of New Drug Application for GSK1838262/XP13512

FDA extends review date of New Drug Application for GSK1838262/XP13512

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