Thrombus News and Research

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A blood clot or thrombus, is the final product of the blood coagulation step in hemostasis. It is achieved via the aggregation of platelets that form a platelet plug, and the activation of the humoral coagulation system (i.e. clotting factors).

UCalgary study could help physicians make better treatment decisions for stroke

More than 80 percent of strokes are caused when a blood vessel to the brain becomes blocked, called an ischemic stroke.

19 Sep 2018

Penumbra introduces new advancements in stroke thrombectomy aspiration technology

Penumbra, Inc., a global healthcare company focused on innovative therapies, today announced U.S. commercial availability of the Penumbra System's most advanced technology: Penumbra JET 7 and Penumbra JET D Reperfusion Catheters powered by the Penumbra ENGINE aspiration source.

4 Sep 2018

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut.

7 Aug 2018

Researchers develop drug-delivery system that allows rapid response to heart attacks

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a drug-delivery system that allows rapid response to heart attacks without surgical intervention.

7 Aug 2018

CERENOVUS announces launch of novel stent retriever for treating stroke patients

CERENOVUS, part of the Johnson & Johnson Medical Devices Companies, announced the first patients have been treated with its new EMBOTRAP II Revascularization Device since it became commercially available in the U.S. EMBOTRAP II is a next-generation stent retriever used to capture and remove life-threatening blood clots from the brain following an ischemic stroke.

26 Jul 2018

Mechanical thrombectomy appears to be important therapy for acute stroke in very old patients

The mechanical removal of blood clots in acute stroke is highly effective but not suitable for all patients.

18 Jun 2018

Powerful clot-busting drugs reserved for selected patients with deep vein thrombosis

Not all patients with blood clots in their legs – a condition known as deep vein thrombosis – need to receive powerful but risky clot-busting drugs, according to results of a large-scale, multicenter clinical trial.

7 Dec 2017

Discovery of natural molecule could lead to effective treatments for gum disease and atherosclerosis

Resolvin E1, a molecule produced naturally in the body from an omega -3 fish oil, topically applied on gum tissues not only prevents and treats gum disease as previously shown (Hasturk et al 2006 and 2007), but also decreases the likelihood for advanced arterial atherosclerotic plaques to rupture and form a dangerous thrombus or blood clot.

16 Nov 2017

High level of heart disease pipeline innovation could bridge unmet need in treating CVD

With over 1,400 products in active development, the innovation pipeline for cardiovascular disease (CVD) is extensive, with four key CVD indications – hypertension, heart failure, dyslipidemia and thrombosis – now accounting for around half of all pipeline innovation, according to GBI Research, a recognized leader in providing business information and analytics.

24 Aug 2017

Novel small molecule tracer for PET imaging spots blood clots

Blood clots in veins and arteries can lead to heart attack, stroke, and pulmonary embolism, which are major causes of mortality.

6 Jul 2017

CWRU researcher receives major NIH grants to develop microscopic drug-delivery systems

Nicole F. Steinmetz, PhD, George J. Picha Professor in Biomaterials, member of the Case Comprehensive Cancer Center, and Director of the Center for Bio-Nanotechnology at Case Western Reserve School of Medicine, has received two major grants from the National Institutes of Health to develop microscopic drug-delivery systems for patients living with breast cancer, and patients at risk for serious blood clots.

29 Jun 2017

Newly developed ultrafast cardiac imaging test changes clinical management in one-third of patients

Researchers in the UK and Peru have developed a faster and cheaper cardiac imaging test that can be used in developing countries, according to the results of the INCA-Peru study presented today at EuroCMR 2017.

26 May 2017

Researchers discover new anti-thrombotic drug target for developing more protective blood thinners

Blood platelets shore up open wounds and help cuts heal, but they can also cause heart attacks and strokes when a congealed ball of platelets known as a thrombus breaks free from a site of injury and gets lodged in blood vessels that feed oxygen to the brain or heart.

24 May 2017

Pulmonary thrombosis-on-a-chip enables unprecedented study of blood responses to organ-level injury

The average human pair of lungs is permeated by a network of about 164 feet of blood vessels (roughly the width of a football field), including microscopic blood capillaries, which facilitate the diffusion of oxygen into the bloodstream in exchange for carbon dioxide.

23 May 2017

Doctors perform first-ever robotic, minimally-invasive surgical removal of stage IV tumor thrombus

A surgical team at Keck Medicine of the University of Southern California has pushed the boundaries of clinical care by performing the first-ever robotic, minimally-invasive surgical removal of a stage IV tumor thrombus, which is when a kidney cancer tumor extends into the heart.

19 Apr 2017

Expert encourages cardiologists to continue using conventional drug-eluting stents

In a New England Journal of Medicine editorial published last week, Debabrata Mukherjee, M.D., provides expert commentary on bioresorbable stents, an alternative to the traditional stents used in patients with cardiac conditions.

6 Apr 2017

OCT offers safe and better guidance for patients undergoing PCI to treat coronary artery disease

Optical coherence tomography (OCT) provides safe and improved guidance for patients undergoing percutaneous coronary intervention to treat coronary artery disease, according to results from the ILLUMIEN III: OPTIMIZE PCI trial.

31 Oct 2016

Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

Researchers from the University of Arkansas for Medical Science (USA), in collaboration with University Hospital Frankfurt and University Hospital Dresden, under the supervision of Prof. Vladimir Zharov and with the participation of Alexander Melerzanov, the dean of Department of Biological and Medical Physics (MIPT), conducted experiments on mice to detect blood clotting using photoacoustic flow-cytometry.

21 Sep 2016

New magnetically controlled drug safe, effective in dissolving blood clots

Critical conditions associated with the blockage of blood vessels are one of the primary health concerns worldwide.

22 Jun 2016

Consensus paper on atrial cardiomyopathies could be important step forward for research, treatment

The first consensus paper on atrial cardiomyopathies is set to be published simultaneously in EP-Europace, HeartRhythm, and the Journal of Arrhythmia. The key contents are launched today at CARDIOSTIM - EHRA EUROPACE 2016.

13 Jun 2016