Wound News and Research

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NLRP3 inflammasome plays dual, time-dependent roles during acute wound healing

Wound healing is a multistep biological process involving inflammation, tissue formation, and remodeling.

2 Mar 2026

How zinc deficiency could worsen heart inflammation and what that means for patients

This review examines how zinc regulates inflammatory and redox signaling pathways involved in myocarditis and pericarditis, highlighting mechanisms such as NF-κB inhibition and the redox zinc switch. The authors conclude that maintaining optimal zinc status may support cardiovascular resilience, while emphasizing that clinical translation requires further targeted trials.

1 Mar 2026

Study maps how NF-κB regulates gene expression in cells

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor dictates the alteration of gene expression in cells.

27 Feb 2026

SolasCure completes Phase II clinical trial, demonstrating accelerated healing with Aurase Wound Gel

SOLASCURE Ltd (SolasCure), a biotechnology company developing a novel treatment to transform chronic wound healing, today announced the successful completion of its second Phase II clinical trial, CLEANVLU2. The study demonstrated that its investigational product, Aurase Wound Gel (AWG), heals chronic wounds at a faster rate than current standard of care, providing clinical validation of its ability to deliver continuous enzymatic debridement while simultaneously activating wound healing.

24 Feb 2026

An Arm and a Leg: Personal finance guru faces down an insurance denial

Less than 36 hours before his wife was scheduled to undergo major surgery, New York Times personal finance columnist Ron Lieber got an unwelcome letter from his family's insurance plan: It was denying prior authorization for the procedure.

19 Feb 2026

Injectable clay-based bandages rapidly stop severe internal bleeding

Traumatic injury is the third leading cause of death in the state of Texas, surpassing strokes, Alzheimer's disease and diabetes, according to the Centers for Disease Control and Prevention.

18 Feb 2026

Developmental ANGPTL4 deficiency protects mice from colitis and tumors

A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation.

18 Feb 2026

Oxygen-delivering gel heals chronic wounds in mice

As aging populations and rising diabetes rates drive an increase in chronic wounds, more patients face the risk of amputations.

17 Feb 2026

Review: Pathogenesis, diagnosis, and management of harlequin ichthyosis

Harlequin ichthyosis (HI) is a rare, severe genetic skin disorder caused by ABCA12 mutations, leading to defective lipid transport and loss of skin barrier function.

17 Feb 2026

Northwestern scientists develop advanced organoid model for human spinal cord injury

Northwestern University scientists have developed the most advanced organoid model for human spinal cord injury to date.

11 Feb 2026

Polygenic analysis provides new insight into hypermobile Ehlers–Danlos syndrome

Hypermobile Ehlers–Danlos syndrome (hEDS) is one of the most common heritable connective tissue disorders.

10 Feb 2026

Study reveals how two key proteins contribute to abnormal bone growth after injury

After serious injuries, burns, fractures, or major surgeries, the body normally repairs damaged tissues and restores movement.

9 Feb 2026

Soft bioelectronic systems for personal health monitoring

Announcing a new article publication for BIO Integration journal. Soft and sustainable wearable bioelectronics are emerging as key platforms for personal health monitoring and digital healthcare.

9 Feb 2026

Bioadhesive patches target remaining glioblastoma cells after surgery

Glioblastoma is the most prevalent and aggressive brain tumor. It proliferates very rapidly, is highly invasive, and there is currently no treatment capable of halting its progression or curing it, which means life expectancy after diagnosis is very short.

6 Feb 2026

Burn injuries may have driven key human evolutionary traits

Humans' exposure to high temperature burn injuries may have played an important role in our evolutionary development, shaping how our bodies heal, fight infection, and sometimes fail under extreme injury, according to new research.

4 Feb 2026

Pigs and grizzly bears may reveal secrets of youthful skin

The secret to youthful appearance and repairing scars may lie in a microscopic skin structure humans share with pigs and grizzly bears - but, surprisingly, not monkeys.

4 Feb 2026

Emotional pain often outweighs fear in post-traumatic stress disorder

New research is challenging the long-held view of post-traumatic stress disorder (PTSD) as a fear-based disorder. In a new study, 68% of trauma-exposed individuals reported that emotional pain (guilt, shame, sadness, loss of joy) impaired their daily functioning more than fear.

4 Feb 2026