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Study uncovers three-way relationships between gut fungi, genetics and disease risk

A new genome-wide study uncovers evidence of the first three-way relationships between human genetic variation, variation in the fungal component of the human microbiome - known as the mycobiome - and risk of developing chronic disease.

9 Sep 2025

Frailty and microbial imbalance drive GI complications in bladder cancer surgery

Gastrointestinal (GI) complications, such as postoperative ileus (POI) and intra-abdominal infections (IAI), remain a major concern after radical cystectomy for bladder cancer.

8 Sep 2025

Study finds links between human genetic variation, gut mycobiome, and chronic disease risk

Clinicians' ability to diagnose and treat chronic diseases is limited by scientific uncertainty around factors contributing to disease risk. A study published September 2nd in the open-access journal PLOS Biology by Drs. Emily Van Syoc, Emily Davenport, and Seth Bordenstein at The Pennsylvania State University, United States, uncovers evidence of the first ternary relationships between human genetic variation, variation in gut mycobiome, and risk of developing chronic disease.

2 Sep 2025

Research reveals molecular details of ME/CFS and long COVID

Patients with chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) have heightened innate immune responses to bacteria, viruses, and fungi. While these responses are essential to fight infection, they can cause damage when unchecked.

1 Sep 2025

How do common painkillers drive stronger E. coli resistance?

Research shows that non-antibiotic medications like ibuprofen can enhance E. coli mutations, raising concerns about antimicrobial resistance in older adults.

29 Aug 2025

Indole chemistry breakthrough opens doors for more effective drug synthesis

Indole, a molecule made up of a six-membered benzene ring fused to a five-membered ring containing nitrogen, forms the core structure of many biologically active compounds.

25 Aug 2025

Virus inside the fungus drives deadly fungal infections

Researchers have discovered that a virus living inside the fungus Aspergillus fumigatus significantly boosts the fungus's ability to survive stress and cause severe infections in mammals.

21 Aug 2025

New strategies to tackle resistant foodborne pathogens

Innovative approaches in food and beverage analysis are transforming pathogen detection and control, emphasizing the role of natural compounds and sequencing.

19 Aug 2025

Light-activated therapy boosts effectiveness of antifungal drugs against Candida albicans

Researchers at the Optics and Photonics Research Center (CePOF) have succeeded in increasing the susceptibility of the fungus Candida albicans to drug treatment through light-activated therapy.

12 Aug 2025

AI discovers promising antibiotic compounds in Archaea microbes

They've survived for billions of years in boiling acid, deep-sea vents and salt flats. Now, some of Earth's oldest life forms - microbes called Archaea - are offering a new weapon in the fight against one of today's most urgent health threats: antibiotic resistance.

12 Aug 2025

Natural gut molecule reverses liver damage and repairs gut lining

UC Davis Health researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure.

12 Aug 2025

Newly discovered drug class could someday lead to breakthrough treatments for fungal infections

A research team at McMaster University has discovered a new drug class that could someday lead to breakthrough treatments for dangerous fungal infections.

11 Aug 2025

Balancing copper antimicrobials to combat antibiotic resistance

Copper has emerged as an ally in the battle against antibiotic-resistant bacteria. Copper sulfate liquids, for example, have been used since the 1700s to control fungal infections in vineyards, orchards and many other kinds of agricultural settings.

8 Aug 2025

Gut bacteria may connect pregnancy diet to childhood autism

Unhealthy maternal diets may alter gut microbes, impacting brain development and increasing autism risk in offspring. Study the microbiome's influence.

8 Aug 2025

KAIST researchers link placental inflammation to childhood allergies

It is already well-known that when a mother experiences inflammation during pregnancy, her child is more likely to develop allergic diseases.

7 Aug 2025

KAIST scientists achieve first total synthesis of herpotrichone with neuroprotective properties

"Herpotrichone" is a natural substance that has been evaluated highly for its excellent ability to suppress inflammation in the brain and protect nerve cells, displaying significant potential to be developed as a therapeutic agent for neurodegenerative brain diseases such as Alzheimer's disease and Parkinson's disease.

5 Aug 2025

Mapping microbiomes across the food system to restore health

Researchers have mapped how microbes underpin healthy food systems—and how we can stop their decline.

1 Aug 2025

Study finds rapid spread of antibiotic-resistant bacteria among malnourished children in Niger

A new study led by researchers at the Ineos Oxford Institute for antimicrobial research (IOI) has found that antimicrobial resistant bacteria is spreading rapidly among children being treated for severe malnutrition in a hospital facility in Niger.

1 Aug 2025

Gut mycobiota could help predict disability in multiple sclerosis

Gut fungal communities may impact multiple sclerosis severity, offering new insights into MS pathogenesis and potential microbiome-based treatment strategies.

29 Jul 2025

Study reveals how the body clock stays on track despite temperature changes

Researchers led by Gen Kurosawa at the RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS) in Japan have used theoretical physics to discover how our biological clock maintains a consistent 24-hour cycle-even as temperatures change.

22 Jul 2025