ACE2 News and Research

RSS

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

The current study looked at the impact of the virus on the CNS in the Syrian golden hamster, a useful animal model for COVID-19.

9 Nov 2021

Novel tetravalent antibodies for the ultrapotent and broad neutralization of SARS-CoV-2 variants

Researchers from the University of Toronto set out to create a new tetravalent antibody that could bind with enough potency that it could remain effective against VOCs.

9 Nov 2021

Scientists develop a high-throughput, cell-free screening platform for anti-SARS-CoV-2 antibody discovery

Scientists from Northwestern University, USA, have recently developed a high-throughput, automated screening platform to rapidly identify anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies. The study is currently available on the bioRxiv* preprint server.

8 Nov 2021

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic lung diseases like COPD and asthma.

8 Nov 2021

Discovery of potent neutralizing antibodies against SARS-CoV-2 variants

In a recent study, the researchers identify and characterize mAbs that are effective against the wild-type SARS-CoV-2 strain and B.1.351 variant.

8 Nov 2021

Study finds SARS-CoV-2 infection of endothelial cells unlikely

Researchers from the University of Queensland have investigated whether infection of endothelial cells with SARS-CoV-2 is possible.

8 Nov 2021

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

A new study describes a new small molecule compound that has shown impressive safety, tolerability, and bioavailability against SARS-CoV-2.

7 Nov 2021

Convalescent plasma post-vaccination increases binding and neutralizing antibodies against SARS-CoV-2 variants

A recent study assesses the boost in antibodies against SARS-CoV-2)variants post-vaccination in plasma samples from previously infected COVID-19 patients.

7 Nov 2021

“Catching SARS-CoV-2 in the act” – viral infection of nasal mucosa spares nerve cells

A new study discusses the entry of SARS-CoV-2 into the respiratory and olfactory mucosa of the nasal cavity.

4 Nov 2021

Novel model-based framework evaluates immune mechanism of COVID-19 vaccine response

A model framework for characterizing viral dynamics and vaccine efficacy in non-human primates is described and applied to the identification of correlates of protection in three independent vaccine studies.

4 Nov 2021

Pre-clinical follow-up study boosting with original formulation and next generation INO-4802 SARS-CoV-2 vaccine candidate

Researchers describe the antibody-inducing effects of DNA-based synthetic vaccines INO-4800 and INO-4802 against SARS-CoV-2 in non-human primates.

3 Nov 2021

Anti-inflammatory diets in COVID-19

A recent review of research published in the journal Diseases has shown that anti-inflammatory diets can be useful in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or reducing the severity of coronavirus disease 2019 (COVID-19).

3 Nov 2021

Isolation of potent neutralizing monoclonal antibodies using nanoparticles displaying SARS-CoV-2 S glycoprotein

A new study aimed to identify several potent neutralizing RBD-directed and NTD-directed mAbs that used a nanoparticle displaying the S glycoprotein to capture SARS-CoV-2-specific B cells.

2 Nov 2021

Identification of common genes in COVID-19 and COPD

Based on protein-protein interactions, the paper shows the presence of ten genes that overlap between the two illnesses, also shared by several other deadly and debilitating diseases.

2 Nov 2021

Placental cell-type productively infected with SARS-CoV-2

A new preprint describes the development of a new platform for evaluating the risk of SARS-CoV-2 infection in placental tissue.

2 Nov 2021

SARS-CoV-2 variants neutralized by camel nanobodies

Researchers from the US recently isolated two VHH nanobodies - 7A3 and 8A2 - from dromedary camels (Camelus dromedaries) using phage display. These nanobodies were found to have a high affinity for the spike RBD and broad neutralization abilities against SARS-CoV-2 and its variants.

2 Nov 2021

ACE2 News and Research

SARS-CoV-2 leaves long-term impact on olfactory neurocircuit

Novel tetravalent antibodies for the ultrapotent and broad neutralization of SARS-CoV-2 variants

Scientists develop a high-throughput, cell-free screening platform for anti-SARS-CoV-2 antibody discovery

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Discovery of potent neutralizing antibodies against SARS-CoV-2 variants

Study finds SARS-CoV-2 infection of endothelial cells unlikely

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

Convalescent plasma post-vaccination increases binding and neutralizing antibodies against SARS-CoV-2 variants

“Catching SARS-CoV-2 in the act” – viral infection of nasal mucosa spares nerve cells

Novel model-based framework evaluates immune mechanism of COVID-19 vaccine response

Pre-clinical follow-up study boosting with original formulation and next generation INO-4802 SARS-CoV-2 vaccine candidate

Anti-inflammatory diets in COVID-19

Isolation of potent neutralizing monoclonal antibodies using nanoparticles displaying SARS-CoV-2 S glycoprotein

Identification of common genes in COVID-19 and COPD

Placental cell-type productively infected with SARS-CoV-2

SARS-CoV-2 variants neutralized by camel nanobodies

Curcumin, a bioactive component of turmeric, effectively neutralizes SARS-CoV-2 in vitro

Study finds inhaled microspheres reduce SARS-CoV-2 infective effectiveness

The impact of SARS-CoV-2 variants on the COVID-19 epidemic in South Africa

New Canadian serology solution for SARS-CoV-2 infections and vaccination

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News