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Study examines if caffeine could prevent harmful effects of PGE1 treatment on breathing

Researchers from the Department of Pediatrics at Case Western Reserve University School of Medicine and University Hospitals Rainbow Babies and Children's Hospital presented results of a study that investigated whether there are any deleterious effects of prostaglandin E1 treatment on breathing and whether these effects would be prevented via pre-treatment with caffeine.

30 Apr 2019

Researchers succeed in humanization of mouse antibodies targeting human herpesvirus 6B

A research group led by Professor Yasuko Mori (Division of Clinical Virology, Center for Infectious Diseases, Kobe University) have succeeded in humanization of mouse antibodies that can neutralize the infection caused by human herpesvirus 6B.

26 Apr 2019

Revolutionary discovery paves new way for treatment of necrotizing enterocolitis

Cutting-edge discovery in the lab of Catherine Hunter, MD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago offers a new direction toward treatment of necrotizing enterocolitis - a devastating intestinal emergency that occurs in up to 10 percent of premature infants

19 Apr 2019

Novo Biosciences achieves major milestones in its new drug to treat heart disease and DMD

Novo Biosciences Inc., has achieved several major milestones in its mission of bringing its breakthrough drug candidate, trodusquemine, to market as a potential regenerative medicine treatment for heart disease and Duchenne muscular dystrophy.

15 Apr 2019

Damaged mitochondria use 'eat me' signals for mitophagy

When mitochondria become damaged, they avoid causing further problems by signaling cellular proteins to degrade them.

12 Apr 2019

New quantum material effectively detects early signs of neurological diseases

What if the brain could detect its own disease? Researchers have been trying to create a material that "thinks" like the brain does, which would be more sensitive to early signs of neurological diseases such as Parkinson's.

11 Apr 2019

Active lifestyle influences regenerative capacity of neurons after spinal cord injury

The influence of an active lifestyle on the regenerative capacity of the peripheral nervous system, that is, the set of cranial and spinal nerves that control motor and sensory functions, is described here for the first time, explains Ángel Barco, who has led the participation of the Institute of Neurosciences UMH-CSIC, in Alicante, in this international study.

11 Apr 2019

Newly developed melanin nanoparticles could slow tumor growth

The dark skin pigment melanin protects us from the sun's damaging rays by absorbing light energy and converting it to heat.

5 Apr 2019

Study evaluates effects of unpaired 1 gene overexpression on lifespan in flies

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS announce the publication of a scientific article titled "Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster" in BMC Systems Biology - an open access journal publishing original peer-reviewed research articles in experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level.

4 Apr 2019

Researchers explore better treatments for irritated tendons

When tendons get irritated it can lead to a serious condition called tendinosis -- a common class of sports and workplace injuries -- which is also common in older individuals. It can take many weeks of rest for tendon irritation to heal, with no treatments, save short-term steroid injections and surgery, followed by more rest.

3 Apr 2019

MUSC study provides evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

Human immunodeficiency virus, or HIV, attacks the immune system, making affected individuals more susceptible to infections. When patients with HIV are treated with antiretroviral therapy, their immune system can recover, but some of them produce self-destructive proteins, or autoantibodies.

2 Apr 2019

Neuroscientists develop new model to trial preventative treatments for schizophrenia

Neuroscientists at The University of Queensland have developed a new animal model of schizophrenia that will enable researchers around the world to better understand the disease and develop new treatments.

30 Mar 2019

Maternal smoking and pre-eclampsia may affect fertility of offspring

Low levels of oxygen in the womb - which can be caused by smoking or conditions such as pre-eclampsia - may cause problems with fertility later in life, a study carried out in rats suggests.

29 Mar 2019

Cancer prevention drug also reduces virulence of H. pylori bacterium

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

29 Mar 2019

Study provides framework for developing Ebola virus therapeutic under FDA Animal Rule

The U.S. Army Medical Research Institute of Infectious Diseases today announced that, for the first time, the U.S. Food and Drug Administration has provided formal regulatory agreement for use of an animal model to support development of a drug candidate, remdesivir, for treating deadly Ebola virus infections.

29 Mar 2019

Purdue engineers develop tiny glutamate sensors for spinal cord injuries

Your chances of getting a nasty migraine increase following a spinal cord injury, thanks to a chemical messenger in the brain that spikes to toxic levels, past studies have suggested.

28 Mar 2019

Aspirin could be used to treat patients with severe tuberculosis infection

Research led by the Centenary Institute in Sydney has found a brand new target for treating drug-resistant tuberculosis; our scientists have uncovered that the tuberculosis bacterium hijacks platelets from the body's blood clotting system to weaken our immune systems.

26 Mar 2019

Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report.

25 Mar 2019

Females on ketogenic diet fail to show metabolic benefits in animal model

The ketogenic diet recently has been touted for weight loss and improving blood sugar control, but a new study finds that females fail to show these metabolic benefits on this high-fat, very low-carbohydrate diet.

25 Mar 2019

TMJ disorders could be treated with tissue-engineered implants after successful animal study

It’s estimated that around 10 million Americans experience a temporomandibular joint (TMJ) disorder, with women being more susceptible than men. Affecting the jaw joint, TMJ disorders are characterized by pain around the jaw, ear, and temple, as well as difficulties in opening the mouth and significant clicking or grinding noises brought on by jaw movement.

21 Mar 2019

Animal Model News and Research

Study examines if caffeine could prevent harmful effects of PGE1 treatment on breathing

Researchers succeed in humanization of mouse antibodies targeting human herpesvirus 6B

Revolutionary discovery paves new way for treatment of necrotizing enterocolitis

Novo Biosciences achieves major milestones in its new drug to treat heart disease and DMD

Damaged mitochondria use 'eat me' signals for mitophagy

New quantum material effectively detects early signs of neurological diseases

Active lifestyle influences regenerative capacity of neurons after spinal cord injury

Newly developed melanin nanoparticles could slow tumor growth

Study evaluates effects of unpaired 1 gene overexpression on lifespan in flies

Researchers explore better treatments for irritated tendons

MUSC study provides evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

Neuroscientists develop new model to trial preventative treatments for schizophrenia

Maternal smoking and pre-eclampsia may affect fertility of offspring

Cancer prevention drug also reduces virulence of H. pylori bacterium

Study provides framework for developing Ebola virus therapeutic under FDA Animal Rule

Purdue engineers develop tiny glutamate sensors for spinal cord injuries

Aspirin could be used to treat patients with severe tuberculosis infection

Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

Females on ketogenic diet fail to show metabolic benefits in animal model

TMJ disorders could be treated with tissue-engineered implants after successful animal study

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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