Cell Death News and Research

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Researchers identify how some cancer cells cheat treatment-induced cell death

Scientists at St. Jude Children's Research Hospital have identified how some cancer cells cheat treatment-induced cell death.

1 Sep 2022

Scientists uncover how a build-up of harmful protein starts to happen in Parkinson's disease

Scientists at the Francis Crick Institute, UCL and the University of Edinburgh have uncovered how a build-up of harmful protein starts to happen within neurons in Parkinson's disease, ultimately causing nerve cell death.

30 Aug 2022

Moffitt study uses computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations

All normal human tissues acquire mutations over time. Some of these mutations may be driver mutations that promote the development of cancer through increased proliferation and survival, while other mutations may be neutral passenger mutations that have no impact on cancer development.

30 Aug 2022

Study uncovers molecular changes in the brain’s blood vessels caused by Alzheimer’s susceptibility gene

Recent breakthroughs have revealed a great deal about Alzheimer's disease, but researchers have yet to paint a complete picture of how genetic risk for the illness causes the brain damage that ultimately leads to memory loss and cognitive decline.

30 Aug 2022

Study reinforces the potential of Huntington’s treatments that target glia cells

Huntington's disease – a hereditary and fatal genetic disorder – has long been considered a neuronal disease due to the permanent loss of medium spiny motor neurons, the death of which over time is responsible for the clinical hallmarks of the disease: involuntary movements, problems with coordination, cognitive decline, depression, and psychosis.

30 Aug 2022

Oncolytic viruses boost the immune capacity to effectively target and destroy cancer cells

The immune system has evolved to safeguard the body from a wildly diverse range of potential threats. Among these are bacterial diseases, including plague, cholera, diphtheria and Lyme disease, and viral contagions such as influenza, Ebola virus and SARS CoV-2.

29 Aug 2022

Cornell research offers insights into CRISPR RNA-guided Caspase system

New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.

25 Aug 2022

Common molecular tool for DNA labelling shows unexpected anticancer properties

Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering a runaway process of DNA repair that is eventually fatal to affected cells, including cancer cells.

23 Aug 2022

Investigating the missing link between COVID-19 and anosmia

A new study evaluated how SARS-CoV-2 infection leads to anosmia via chromatin structure disruption and OR dysregulation. For this purpose, publicly available Hi-C data of OSNs of SARS-CoV-2-infected and control human subjects were used.

23 Aug 2022

Researchers assess the cytoprotective activity of nicotine against COVID-19

In a newly released study, researchers assessed the cytoprotective activity of nicotine against COVID-19.

23 Aug 2022

Increasing the production of new neurons rescues memory defects in mice with Alzheimer's disease

Researchers at the University of Illinois Chicago have discovered that increasing the production of new neurons in mice with Alzheimer's disease (AD) rescues the animals' memory defects.

19 Aug 2022

Scientists identify new driver for rare type of liver cancer

Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Hebrew University in Jerusalem have identified in mice the cell of origin of combined liver/biliary duct carcinomas, a rare type of cancer of the liver.

19 Aug 2022

Researchers assess lutein nanodisks against ultraviolet light-induced retinal damage

Researchers assessed the role of lutein nanodisks against ultraviolet (UV) light-induced damage to retinal cells.

18 Aug 2022

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

New research led by scientists at Mass Eye and Ear and Brigham and Women's Hospital, member hospitals of Mass General Brigham, reveals the role that a genetic variant associated with Alzheimer's disease, APOE4, plays in protecting against glaucoma.

16 Aug 2022

Study paves new way to develop a predictive biomarker for TRAIL therapy

A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Therefore, various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, but a certain population of cancer patients does not respond to the therapy.

15 Aug 2022

What is the impact of COVID-19 on male reproductive health?

In a recent study, researchers assessed male reproductive health three months after COVID-19 infection.

12 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

Repurposed drug shows promise as potential new treatment for motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.

11 Aug 2022

Study aims to understand how female fertility is established at the molecular level

Fertility is finite for mammalian females. From birth, females possess a limited number of primordial follicles, collectively called the ovarian reserve. Within each follicle is an oocyte that eventually becomes an egg. But with age, the follicles in the ovarian reserve decrease.

11 Aug 2022

Research may lead the way to a simpler treatment for cancer

Sometimes too much of a good thing is not good at all. Inhibiting the function of the PD-1 protein, which blocks immune function, has shown high therapeutic efficacy in cancer immunotherapy.

10 Aug 2022

Cell Death News and Research

Researchers identify how some cancer cells cheat treatment-induced cell death

Scientists uncover how a build-up of harmful protein starts to happen in Parkinson's disease

Moffitt study uses computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations

Study uncovers molecular changes in the brain’s blood vessels caused by Alzheimer’s susceptibility gene

Study reinforces the potential of Huntington’s treatments that target glia cells

Oncolytic viruses boost the immune capacity to effectively target and destroy cancer cells

Cornell research offers insights into CRISPR RNA-guided Caspase system

Common molecular tool for DNA labelling shows unexpected anticancer properties

Investigating the missing link between COVID-19 and anosmia

Researchers assess the cytoprotective activity of nicotine against COVID-19

Increasing the production of new neurons rescues memory defects in mice with Alzheimer's disease

Scientists identify new driver for rare type of liver cancer

Researchers assess lutein nanodisks against ultraviolet light-induced retinal damage

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

Study paves new way to develop a predictive biomarker for TRAIL therapy

What is the impact of COVID-19 on male reproductive health?

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

Repurposed drug shows promise as potential new treatment for motor neuron disease

Study aims to understand how female fertility is established at the molecular level

Research may lead the way to a simpler treatment for cancer

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