Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Most Canadians view financial incentives for deceased kidney donation to be acceptable

Most Canadians view financial incentives for deceased kidney donation to be acceptable, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

28 Sep 2012

Two-part ACR guidelines on gout

Gout is one of the most common forms of inflammatory arthritis, affecting nearly 4% of adult Americans. Newly approved guidelines that educate patients in effective methods to prevent gout attacks and provide physicians with recommended therapies for long-term management of this painful disease are published in Arthritis Care & Research, a peer-reviewed journal of the American College of Rheumatology (ACR).

28 Sep 2012

FDA, American Society of Nephrology announce Kidney Health Initiative

The American Society of Nephrology (ASN) and the US Food and Drug Administration (FDA) are pleased to announce a new partnership: the Kidney Health Initiative (KHI).

28 Sep 2012

NOXXON commences NOX-A12 Phase IIa trial in relapsed MM

NOXXON Pharma today announced the treatment of the first cohort of three multiple myeloma (MM) patients in a Phase IIa clinical trial of its anti-CXCL12/SDF-1 (CXC chemokine ligand 12 / Stromal Cell-Derived Factor-1) Spiegelmer NOX-A12.

26 Sep 2012

Kidney disease linked with risk of death and ESRD even in patients without hypertension or diabetes

Two new studies from the Johns Hopkins Bloomberg School of Public Health and the Chronic Kidney Disease Prognosis Consortium found that the presence of chronic kidney disease itself can be a strong indicator of the risk of death and end-stage renal disease (ESRD) even in patients without hypertension or diabetes.

26 Sep 2012

Low aerobic fitness risk factor for chronic kidney disease in men

Young men with low levels of aerobic fitness are more likely to have albuminuria or glomerular hyperfiltration, both early signs of chronic kidney disease, than those with higher levels of fitness.

24 Sep 2012

Absence of proteinuria good prognostic sign in IgA nephropathy

The presence of normal renal function and minor urinary abnormalities indicates a good long-term prognosis among Caucasian patients with immunoglobulin A nephropathy, say Spanish researchers.

24 Sep 2012

Study to examine SYMPLICITY renal denervation system for treatment-resistant hypertension

The University of Michigan Cardiovascular Center will participate in a national clinical trial to treat the most challenging form of high blood pressure.

24 Sep 2012

Children with mild to moderate kidney disease have carotid atherosclerosis

A federally funded study led by researchers at Johns Hopkins Children's Center has found that children with mild to moderate kidney disease have abnormally thick neck arteries, a condition known as carotid atherosclerosis, usually seen in older adults with a long history of elevated cholesterol and untreated hypertension.

21 Sep 2012

Cytochroma commences CTAP101 phase 3 study in secondary hyperparathyroidism

Cytochroma today announced the initiation of a phase 3 study of CTAP101 capsules in patients with secondary hyperparathyroidism (SHPT), stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.

21 Sep 2012

PCA inhibits multiple pathways involved in development of diabetic nephropathy

Diabetic nephropathy is one of the most serious complications related to diabetes, often leading to end-stage kidney disease. Purple corn grown in Peru and Chile is a relative of blue corn, which is readily available in the U.S.

20 Sep 2012

Aerpio Therapeutics commences AKB-9778 Phase 1b/2a trial in diabetic macular edema

Aerpio Therapeutics, a clinical-stage biopharmaceutical company developing innovative therapies for vascular diseases by targeting the Tie2 pathway, today announced that it has dosed the first patient in a Phase 1b/2a trial of AKB-9778 for the treatment of diabetic macular edema (DME).

20 Sep 2012

Age at diabetes onset linked to macular edema onset

Older age at onset of Type 1 diabetes significantly increases the risk for developing clinically significant macular edema, show study findings.

19 Sep 2012

Measures of kidney function may be linked to thrombosis

Estimated glomerular filtration rate and albumin-creatinine ratio are independently associated with venous thromboembolism, research suggests.

18 Sep 2012

Measures of kidney function may be linked to thrombosis

Estimated glomerular filtration rate and albumin-creatinine ratio are independently associated with venous thromboembolism, research suggests.

18 Sep 2012

Orthopedists should suspect necrotizing fasciitis in patients with out of proportion pain

Dr. Russell Russo, an Orthopedic Surgeon at LSU Health Sciences Center New Orleans, and other researchers stress that orthopedists should have a high index of suspicion for necrotizing fasciitis, or flesh-eating bacterial infection, in every patient with pain or other symptoms that are out of proportion to the initial diagnosis. Their recommendations are published in the September 2012 issue of Orthopedics Today.

17 Sep 2012

Anthera to initiate blisibimod Phase 3 program for systemic lupus erythematosus

Anthera Pharmaceuticals, Inc., a biopharmaceutical company developing drugs to treat serious diseases associated with inflammation and autoimmune disorders, today provided an update on regulatory discussions for the global development of blisibimod.

17 Sep 2012

Researchers investigate African plants effective in treating snakebite

A PhD student at the University of Copenhagen has drawn on nature's own pharmacy to help improve the treatment of snakebites in Africa.

17 Sep 2012

ASN's top five recommendations to avoid wasteful and harmful medical interventions

Earlier this year, the American Society of Nephrology (ASN), the world's leading kidney organization, joined other groups in a campaign to help health care professionals and patients avoid wasteful and sometimes harmful medical interventions. A new article in the Clinical Journal of the American Society of Nephrology (CJASN) outlines the ASN's top five recommendations for the campaign and the rationale behind them.

14 Sep 2012

Viewpoints: Romney's whiplash on health law; Clinton's mistaken argument about Medicare savings

At first glance, it looked like Republican presidential nominee Mitt Romney had once again altered his position on healthcare reform. "I'm not getting rid of all of healthcare reform," he said on "Meet the Press" over the weekend.

12 Sep 2012

Nephropathy News and Research

Further Reading

Most Canadians view financial incentives for deceased kidney donation to be acceptable

Two-part ACR guidelines on gout

FDA, American Society of Nephrology announce Kidney Health Initiative

NOXXON commences NOX-A12 Phase IIa trial in relapsed MM

Kidney disease linked with risk of death and ESRD even in patients without hypertension or diabetes

Low aerobic fitness risk factor for chronic kidney disease in men

Absence of proteinuria good prognostic sign in IgA nephropathy

Study to examine SYMPLICITY renal denervation system for treatment-resistant hypertension

Children with mild to moderate kidney disease have carotid atherosclerosis

Cytochroma commences CTAP101 phase 3 study in secondary hyperparathyroidism

PCA inhibits multiple pathways involved in development of diabetic nephropathy

Aerpio Therapeutics commences AKB-9778 Phase 1b/2a trial in diabetic macular edema

Age at diabetes onset linked to macular edema onset

Measures of kidney function may be linked to thrombosis

Measures of kidney function may be linked to thrombosis

Orthopedists should suspect necrotizing fasciitis in patients with out of proportion pain

Anthera to initiate blisibimod Phase 3 program for systemic lupus erythematosus

Researchers investigate African plants effective in treating snakebite

ASN's top five recommendations to avoid wasteful and harmful medical interventions

Viewpoints: Romney's whiplash on health law; Clinton's mistaken argument about Medicare savings

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