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New biodegradable nanoprobes could help detect cancer more accurately

New Imperial-developed nanoprobes tested in zebrafish could help detect cancer more accurately and might aid diagnosis and therapy in the future.

11 Mar 2021

Is a single mRNA COVID-19 vaccine dose enough for recovered individuals?

A new study deals with the evaluation of adaptive immune response to COVID-19 vaccination in candidates who have recovered from SARS-CoV-2 infection.

11 Mar 2021

Information from ancient teeth could reveal new insights about the past

There's a surprising amount of information stored in the hardened plaque, or calculus, between teeth. And if that calculus belongs to the remains of a person who lived in ancient times, the information could reveal new insights about the past.

11 Mar 2021

Researchers confirm new drug development route for treating multiple sclerosis, asthma

Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma.

10 Mar 2021

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

9 Mar 2021

SARS-CoV-2's amyloid-driving nucleoprotein could inform future therapeutic research

New research led by researchers at the University of California Los Angeles and the University of Texas Southwestern Medical Center in the US suggests that functional amyloid fibrils could play an integral role in developing COVID-19 treatments.

9 Mar 2021

Optimized SARS-CoV-2 vaccine candidate could be less reactogenic, say researchers

A new study, released as a preprint on the bioRxiv* server, reports an optimized coronavirus disease 2019 (COVID-19) vaccine candidate, which, claim the researchers, may be less likely to produce reactions like fevers. It may also have increased protective potential against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19.

9 Mar 2021

Bruker announces new results in deep, unbiased plasma proteomics, PaSER 1.1 software and new cross-linking consumables at US HUPO 2021

At the virtual 17th US HUPO Conference (US HUPO 2021), Bruker Corporation (Nasdaq: BRKR) today announces progress with several collaborations in deep, unbiased plasma proteomics, leveraging the speed, sensitivity and dynamic range of 4D proteomics on timsTOF Pro systems.

From Bruker Daltonics 9 Mar 2021

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

The currently developed vaccines against SARS-CoV-2 include the RBD in their immunogen. With a similar objective, a new study developed an RBD protein-based vaccine candidate against the SARS-CoV-2, using self-assembling Helicobacter pylori-bullfrog ferritin nanoparticles as an antigen delivery system. The study is published recently in the journal mBio (by the American Society of Microbiology).

8 Mar 2021

SARS-CoV-2-derived mutant peptides hamper T cells' ability to recognize and destroy infected cells

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

4 Mar 2021

The Role of D-Amino Acids in Humans

In this interview, Dr. Daniel Armstrong from the University of Texas at Arlington talks to News-Medical Life Sciences about his upcoming Pittcon presentation.

From Pittcon 4 Mar 2021

New Nature Communications publication by Mann & Theis Groups harnesses the benefits of large-scale peptide collisional cross section (CCS) measurements and deep learning for 4D-proteomics

Bruker Corporation today announces a seminal publication from the groups of Professors Matthias Mann and Fabian Theis in the journal Nature Communications with the title ‘Deep learning the collisional cross sections of the peptide universe from a million experimental values’ by Florian Meier et al.

From Bruker Daltonics 4 Mar 2021

SARS-CoV-2 variants do not substantially affect CD4+ and CD8+ T cell responses, study shows

Researchers from California in the United States have conducted a study showing that important adaptive immune responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are not affected by four recently emerged variants of the virus.

3 Mar 2021

Novel drug for preventing Alzheimer's disease found to be safe and effective in animals

Researchers at the University of California San Diego School of Medicine and Massachusetts General Hospital have identified a new drug that could prevent Alzheimer's disease by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques in the brain.

2 Mar 2021

New drug could prevent Alzheimer's by modulating key enzyme involved in amyloid plaque formation

Amyloid plaques are pathological hallmarks of Alzheimer's disease (AD) -- clumps of misfolded proteins that accumulate in the brain, disrupting and killing neurons and resulting in the progressive cognitive impairment that is characteristic of the widespread neurological disorder.

2 Mar 2021

Could small synthetic antigen proteins be diagnostic tools for SARS-CoV-2?

Researchers have developed small proteins from sequences in SARS-CoV-2's RBD that bind to ACE2. These were as effective in binding to neutralizing antibodies as larger RBD proteins.

2 Mar 2021

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.

1 Mar 2021

Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

A new study by researchers at Imperial College London, UK, discusses the effect of a vaccine dose, specifically the BNT162b2 candidate (also known as the ‘Pfizer-BioNTech’ vaccine), on neutralizing antibody titers in individuals who have already been infected with the virus.

1 Mar 2021

Study reveals molecular details of SARS-CoV-2 interactions with human cells

In order to infect cells, SARS-CoV-2, the virus that causes COVID-19, needs to insert itself into the membrane of human cells. New molecular models show what parts of SARS-CoV-2 are critical for that interaction, revealing new potential drug targets.

25 Feb 2021

Study reports lasting immune response in convalescent COVID-19 patients

Researchers report the cellular immune response of convalescent patients in Germany, who recovered from mild or moderate infection compared to that of healthy people with no history of COVID-19.

25 Feb 2021

Peptides News and Research

New biodegradable nanoprobes could help detect cancer more accurately

Is a single mRNA COVID-19 vaccine dose enough for recovered individuals?

Information from ancient teeth could reveal new insights about the past

Researchers confirm new drug development route for treating multiple sclerosis, asthma

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

SARS-CoV-2's amyloid-driving nucleoprotein could inform future therapeutic research

Optimized SARS-CoV-2 vaccine candidate could be less reactogenic, say researchers

Bruker announces new results in deep, unbiased plasma proteomics, PaSER 1.1 software and new cross-linking consumables at US HUPO 2021

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

SARS-CoV-2-derived mutant peptides hamper T cells' ability to recognize and destroy infected cells

The Role of D-Amino Acids in Humans

New Nature Communications publication by Mann & Theis Groups harnesses the benefits of large-scale peptide collisional cross section (CCS) measurements and deep learning for 4D-proteomics

SARS-CoV-2 variants do not substantially affect CD4+ and CD8+ T cell responses, study shows

Novel drug for preventing Alzheimer's disease found to be safe and effective in animals

New drug could prevent Alzheimer's by modulating key enzyme involved in amyloid plaque formation

Could small synthetic antigen proteins be diagnostic tools for SARS-CoV-2?

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

Study reveals molecular details of SARS-CoV-2 interactions with human cells

Study reports lasting immune response in convalescent COVID-19 patients

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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