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Study reports an increase in incidence of islet autoimmunity after SARS-CoV-2 infection in young children

Type 1 diabetes is an autoimmune disease leading to an impaired glucose metabolism and requires life-long administration of insulin.

8 Sep 2023

Zebrafish study unravels how the brain orchestrates motion

The zebrafish brain, though simpler than its human counterpart, is a complex network of neurons that engage in a ceaseless dance of electrical activity.

8 Sep 2023

New way to administer CAR-T-cell therapy could lead to fewer side effects

When Richard O'Neil, Ph.D., joined MUSC Hollings Cancer Center two years ago, he knew that he wanted to continue finding ways to make CAR-T-cell therapy easier on patients.

8 Sep 2023

Blood clots may be a cause of long-term cognitive problems after COVID-19

High levels of two proteins at the time of COVID-19 have been found in patients who later experienced cognitive problems, including 'brain fog', giving a major clue as to one cause of their symptoms: blood clots.

7 Sep 2023

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Researchers reviewed the evidence for SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC).

6 Sep 2023

Could a new framework for aging biomarkers revolutionize how we understand and treat the aging process?

A comprehensive review in the journal Cell outlines a unified framework for classifying and validating aging biomarkers, aiming to streamline their integration into clinical research and practice. The study categorizes biomarkers into types like molecular, functional, and clinical, and sets criteria for their feasibility, validity, and applicability, all with the goal of better understanding and intervening in the aging process.

5 Sep 2023

New tool can diagnose autism in children as young as 16 months

Results of clinical studies published simultaneously today in the Journal of the American Medical Association (JAMA) and in JAMA Network Open demonstrate that measuring children's looking behavior predicts expert clinical diagnosis of autism in children between ages 16 to 30 months tested with a high degree of accuracy.

5 Sep 2023

New study highlights impact of COVID-19 pandemic on emergency department visits in British Columbia

A new study showing the impact of the COVID-19 pandemic and mitigation strategies used to manage the virus on emergency department (ED) visits in British Columbia can help with future planning.

5 Sep 2023

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Researchers investigated the impact of biological sex on protein levels and its genomic control by analyzing 1,277 proteomes of the brain.

4 Sep 2023

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

Amgen today announced data from the final analysis of the Phase 2 OCEAN(a)-DOSE study of olpasiran, a small interfering RNA (siRNA) during the Late-Breaking Science Session at the European Society of Cardiology (ESC) Annual Meeting being held in Amsterdam. In the off-treatment extension period, olpasiran showed a lasting effect on Lp(a) reduction nearly a year after the last dose.

From AMGEN 1 Sep 2023

Peer-delivered psychotherapy effective for postpartum depression

An innovative model of care that offers new mothers psychotherapy delivered by other mothers who have also experienced post-partum depression (PPD) should be implemented in clinical practice, according to researchers at McMaster University.

31 Aug 2023

Controlling traditional cardiovascular risk factors can prevent Alzheimer's and other dementias

Cardiovascular disease and dementia frequently occur together in elderly people. Nevertheless, few longitudinal studies have examined how atherosclerosis and its associated risk factors affect brain health from middle age.

30 Aug 2023

Light-driven bacteria could be used to target and kill cancer cells

Targeting malignant tumors with high precision is challenging for biomedical researchers. However, this scenario is likely to witness a paradigm shift in the near future, through the use of specially engineered bacteria, that can eliminate malignant cells efficiently.

29 Aug 2023

New research sheds light on role of KRAS mutations in pancreatic cancer

Researchers at The University of Texas MD Anderson Cancer Center have uncovered a functional role for KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a KRAS G12D inhibitor with immune checkpoint inhibitors for early- and late-stage KRAS G12D-mutant pancreatic cancer.

24 Aug 2023

The most recent neuroimaging procedures and machine learning approaches for the prediction of Alzheimer’s progression

Researchers examined recent studies exploring neuroimaging modalities aided by advanced machine learning (ML) algorithms.

24 Aug 2023

Long-read sequencing reveals new details of Bartter syndrome type 3

Bartter syndrome type 3 is the result of several structural variants in the genome. By using long-read sequencing, Janine Altmüller and her team from the Max Delbrück Center, the BIH and University Hospital Cologne mapped out the rare disease in unprecedented detail.

23 Aug 2023

New kidney tissue model could help assess safety of immunotherapy drugs

A growing repertoire of cell and molecule-based immunotherapies is offering patients with indomitable cancers new hope by mobilizing their immune systems against tumor cells.

23 Aug 2023

UT Health San Antonio and partners secure NIH funding to translate scientific discoveries into therapeutic benefits

The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) and seven regional collaborators will leverage $46 million from the National Institutes of Health (NIH) over the next five to seven years to translate scientific discoveries into therapeutic benefits for human health and well-being.

22 Aug 2023

$2.8 million awarded to translate research on how cancer cells evolve and compete into patient care

The National Institutes of Health recently awarded Cleveland Clinic's Jacob Scott, M.D., D.Phil., and collaborators $2.8 million to translate research on how cancer cells evolve and compete into patient care.

22 Aug 2023

New method could make single-cell RNA sequencing more accessible to patients

To improve therapies for cancer and other diseases, researchers strive to identify tissue-specific therapeutic targets and diagnostic biomarkers in every patient.

22 Aug 2023

Translation News and Research

Study reports an increase in incidence of islet autoimmunity after SARS-CoV-2 infection in young children

Zebrafish study unravels how the brain orchestrates motion

New way to administer CAR-T-cell therapy could lead to fewer side effects

Blood clots may be a cause of long-term cognitive problems after COVID-19

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Could a new framework for aging biomarkers revolutionize how we understand and treat the aging process?

New tool can diagnose autism in children as young as 16 months

New study highlights impact of COVID-19 pandemic on emergency department visits in British Columbia

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

Peer-delivered psychotherapy effective for postpartum depression

Controlling traditional cardiovascular risk factors can prevent Alzheimer's and other dementias

Light-driven bacteria could be used to target and kill cancer cells

New research sheds light on role of KRAS mutations in pancreatic cancer

The most recent neuroimaging procedures and machine learning approaches for the prediction of Alzheimer’s progression

Long-read sequencing reveals new details of Bartter syndrome type 3

New kidney tissue model could help assess safety of immunotherapy drugs

UT Health San Antonio and partners secure NIH funding to translate scientific discoveries into therapeutic benefits

$2.8 million awarded to translate research on how cancer cells evolve and compete into patient care

New method could make single-cell RNA sequencing more accessible to patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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