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Domestic animals less likely to be major source of antibiotic resistant Salmonella in humans

A new study has shown that, contrary to popular belief, local domestic animals are unlikely to be the major source of antibiotic resistant Salmonella in humans. The result comes from a detailed study of DNA from more than 370 Salmonella samples collected over a 22-year period.

13 Sep 2013

Researchers show network of genes which enforce cooperative state within cells

We often think of human cells as tiny computers that perform assigned tasks, where disease is a result of a malfunction. But in the current issue of Science, researchers at The Mount Sinai Medical Center offer a radical view of health — seeing it more as a cooperative state among cells, while they see disease as result of cells at war that fight with each other for domination.

13 Sep 2013

Viewpoints: GOP 'obsession' with health law prevents progress on key financial issues; the 'fantasy of fertility;' VA is 'model' for transforming U.S. medicine

Try as they might, House Republican leaders are having trouble stopping their colleagues from shooting themselves in the foot -- again. Having failed to approve any of the 12 annual appropriations bills that fund federal agencies, Congress has to pass a stopgap spending bill by Sept. 30 to keep much of the federal government from shutting down.

13 Sep 2013

Pancreatic protein essential for maintaining functional state of beta cells

Researchers at the Pediatric Diabetes Research Center (PDRC) at the University of California, San Diego School of Medicine have shown that the pancreatic protein Nkx6.1 - a beta-cell enriched transcription factor - is essential to maintaining the functional state of beta cells.

13 Sep 2013

P3G and CGP launch International Policy interoperability and data Access Clearinghouse

Since the sequence map of the human genome, the cost of sequencing the genome of an individual has fallen rapidly. This has resulted in a tremendous increase in the amount of human genomic data available to the international research community for the advancement of biomedical research. Yet, there is an absence of international mechanisms to support researchers in ensuring ethical and legal interoperability. In addition, the multiplicity and diversity of laws, standards and policies on sharing and accessing genetic and medical data represent major hurdles to international collaboration.

12 Sep 2013

Mount Sinai physician-scientists join DILIN to help find causes, diagnostics for drug-induced liver injury

In an effort to better understand and develop prevention strategies for drug-induced liver injury, physician-scientists from the Icahn School of Medicine at Mount Sinai have joined the Drug-Induced Liver Injury Network, a National Institutes of Health-funded consortium of only six academic medical centers in the United States.

12 Sep 2013

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

A family of microRNAs (miR-200) blocks cancer progression and metastasis by stifling a tumor's ability to weave new blood vessels to support itself, researchers at The University of Texas MD Anderson Cancer Center report today in Nature Communications.

12 Sep 2013

New research explains how DNA strands repair themselves

Researchers have discovered the details of how cells repair breaks in both strands of their DNA, a potentially devastating kind of DNA damage.

12 Sep 2013

Scientists discover that copper alloys shut down highly infectious norovirus

Scientists from the University of Southampton have discovered that copper and copper alloys rapidly destroy norovirus - the highly-infectious sickness bug.

12 Sep 2013

Genia Technologies receives $5M grant from NIH to develop nanopore-based DNA sequencing platform

Genia Technologies, Inc. today announced that the company, as part of a research consortium with Columbia University and Harvard Medical School, received a Revolutionary Genome Sequencing Technologies – The $1,000 Genome grant from the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH).

12 Sep 2013

Professor to develop DNA sequencing technologies to search for long-range genome interactions

Why do some people develop disease while others with the same genetic mutation don't? For example, the National Cancer Institute estimates that women who inherit a harmful BRCA2 mutation have a 45 percent chance of developing breast cancer by age 70.

11 Sep 2013

Researchers discover 4 novel gene variations linked with blood pressure

Case Western Reserve University is part of a landmark study that has discovered four novel gene variations associated with blood pressure. The 19-site meta-analysis, involving nearly 30,000 African-Americans, also found that the set of genetic mutations are also associated with blood pressure across other populations.

11 Sep 2013

Bayer, Broad On Five-Year Mission To Search For Novel Cancer Therapeutics

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10 Sep 2013

Biologists identify two pathways via which chromosomes are rearranged

Biologists reported today in Nature that they have identified two pathways through which chromosomes are rearranged in mammalian cells. These types of changes are associated with some cancers and inherited disorders in people.

10 Sep 2013

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Scientists have developed a strain of the Middle East respiratory syndrome coronavirus (MERS-CoV) that could be used as a vaccine against the disease, according to a study to be published in mBio-, the online open-access journal of the American Society for Microbiology.

10 Sep 2013

Scientists identify RNA regulator that plays critical role in proper functioning of hESCs

Scientists at A*STAR's Genome Institute of Singapore, in collaboration with their counterparts from Canada, Hong Kong and US, have discovered a protein mediator SON plays a critical role in the health and proper functioning of human embryonic stem cells. This finding was reported on 8th September 2013 in the advanced online issue of the prestigious science journal Nature Cell Biology.

10 Sep 2013

Two Pathways Found Through Which Chromosomes Are Rearranged

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9 Sep 2013

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

The Institute for Translational Medicine and Therapeutics' 7th Annual International Symposium (ITMAT) symposium, Harnessing the Paradox: Personalization and the Science of Scale, to be held in October 2013, will address topics of direct relevance to translational science.

7 Sep 2013

Research team receives nearly $17M to focus on nanopore technology in DNA sequencing

The use of nanopore technology aimed at more accurate and efficient DNA sequencing is the main focus of grants awarded by the National Institutes of Health. The grants - nearly $17 million to eight research teams - are the latest awarded through the National Human Genome Research Institute (NHGRI)'s Advanced DNA Sequencing Technology program, which was launched in 2004. NHGRI is part of NIH.

7 Sep 2013

NIH awards nearly $14M grants to research on how genetic factors influence susceptibility to disease

Five research teams have received new four-year awards to study the genomics of disease susceptibility in ethnically diverse populations. The projects aim to unravel the subtle variations in genetic makeup among groups - including African-Americans, Asian-Americans, Hispanics and more - that may account for differences in risks for conditions such as high blood pressure and high blood lipids, in addition to common diseases such as cancer and heart disease.

7 Sep 2013

Genome News and Research

Domestic animals less likely to be major source of antibiotic resistant Salmonella in humans

Researchers show network of genes which enforce cooperative state within cells

Viewpoints: GOP 'obsession' with health law prevents progress on key financial issues; the 'fantasy of fertility;' VA is 'model' for transforming U.S. medicine

Pancreatic protein essential for maintaining functional state of beta cells

P3G and CGP launch International Policy interoperability and data Access Clearinghouse

Mount Sinai physician-scientists join DILIN to help find causes, diagnostics for drug-induced liver injury

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

New research explains how DNA strands repair themselves

Scientists discover that copper alloys shut down highly infectious norovirus

Genia Technologies receives $5M grant from NIH to develop nanopore-based DNA sequencing platform

Professor to develop DNA sequencing technologies to search for long-range genome interactions

Researchers discover 4 novel gene variations linked with blood pressure

Bayer, Broad On Five-Year Mission To Search For Novel Cancer Therapeutics

Biologists identify two pathways via which chromosomes are rearranged

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Scientists identify RNA regulator that plays critical role in proper functioning of hESCs

Two Pathways Found Through Which Chromosomes Are Rearranged

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

Research team receives nearly $17M to focus on nanopore technology in DNA sequencing

NIH awards nearly $14M grants to research on how genetic factors influence susceptibility to disease

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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