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Immunologists discover how rescue proteins delay ‘executioner’ machinery that kills damaged cells

A research team led by St. Jude Children's Research Hospital immunologists has discovered how a set of proteins delays the "executioner" machinery that kills damaged or infected cells in a process called necroptosis.

7 Apr 2017

Study of interactions between chemokines pinpoints potential targets for treatment of inflammation

Signal molecules called chemokines often work in tandem to recruit specific sets of immune cells to sites of tissue damage.

7 Apr 2017

Researchers uncover critical pathway that helps pancreatic cancer cells turn off immune system

Researchers at NYU Langone Medical Center and its Perlmutter Cancer Center have uncovered a critical pathway by which pancreatic cancer cells turn off the immune system charged with attacking them. The findings appear in a paper published online in Nature Medicine April 10.

7 Apr 2017

Infection with reovirus could be key initiating event for developing celiac disease, study suggests

Infection with reovirus, a common but otherwise harmless virus, can trigger the immune system response to gluten that leads to celiac disease, according to new research from the University of Chicago and the University of Pittsburgh School of Medicine.

6 Apr 2017

Cancer uses immature immune cells as support system for successful metastasis, study shows

More typically, these immature immune cells might help us fight cancer, but scientists have now shown cancer can commandeer the cells to help it spread.

6 Apr 2017

Tumor necrosis factor may help control blood pressure, study suggests

Investigators at the Ted Rogers Centre for Heart Research have discovered a surprising new role for tumor necrosis factor (TNF): namely, that it is a major regulator of small blood vessel function, the key determinant of blood pressure. The study is published online today in Nature Communications.

6 Apr 2017

Researchers solve medical mystery through genetics

Researchers have identified the genetic mutation responsible for one patient's serious health problems, finally solving a medical mystery that has endured for over 30 years.

6 Apr 2017

Case Western Reserve University researchers aim to treat oral complications of HIV

While advances in HIV treatment have dramatically improved patient lifespans and quality of life, nagging side effects remain; among the most common is chronic inflammation--essentially, when an immune system imbalance causes the body to attack itself.

6 Apr 2017

Researchers develop stable brain implant based on anti-inflammatory coating

Complex neurotechnological devices are required to directly select and influence brain waves inside the skull's interior. Although it has become relatively easy to implement the devices, researchers are still faced with challenges when trying to keep them running properly in living organisms over time.

5 Apr 2017

Experimental treatment cures Marburg and Ravn virus infection in animals

Scientists funded by the National Institutes of Health have found that an experimental treatment cured 100 percent of guinea pigs and rhesus monkeys in late stages of infection with lethal levels of Marburg and Ravn viruses, relatives of the Ebola virus.

5 Apr 2017

Researchers achieve new step towards treatment of myotubular myopathy using gene therapy

A team of researchers in France, led by Dr. Ana Buj-Bello (Genethon/Inserm) and teams at the University of Washington and Harvard Medical School in the United States, achieved a new step towards the treatment of myotubular myopathy by gene therapy.

5 Apr 2017

Probiotics may help treat yeast infections, bowel problems in men with schizophrenia

In a small pilot study of men with schizophrenia, researchers at Johns Hopkins Medicine and Sheppard Pratt Health System say they have evidence that adding probiotics -- microorganisms, such as bacteria found in yogurts -- to the patients' diets may help treat yeast infections and ease bowel problems.

5 Apr 2017

Number of HIV-positive cancer patients in the U.S. projected to decrease through 2030

As the population of people living with HIV in the United States ages, the burden of cancer for these patients is expected to shift away from cancers linked to AIDS and toward malignancies that affect the general population, according to a new study led by a University of North Carolina at Chapel Hill researcher.

5 Apr 2017

Tumor microenvironment poses unique challenges for effective ovarian cancer T-cell therapy

Fred Hutchinson Cancer Research Center immunotherapy researchers Drs. Kristin Anderson and Philip Greenberg and their colleagues are working on ways to tweak their team's early successes with T-cell therapy for leukemia to apply to solid tumors.

5 Apr 2017

Researchers discover possible new route to regenerating function lost in diabetes

In people with type I diabetes, insulin-producing beta cells in the pancreas die and are not replaced. Without these cells, the body loses the ability to control blood glucose.

4 Apr 2017

Meningitis bacterium appears to be adapting to urogenital environment, DNA analysis shows

Neisseria meningitidis, a bacterium usually associated with meningitis and sepsis, is the cause of a recent cluster of sexually transmitted infections in Columbus, Ohio and in other US cities. The bacterium appears to be adapting to a urogenital environment, an analysis of the organism's DNA shows.

4 Apr 2017

Global symposium focuses on chemistry and biological effects of maple food product

The first-ever global symposium, solely dedicated to sharing the latest scientific discoveries on the potential health benefits of 100% pure maple products from Canada, took place on April 2 in San Francisco at the 253rd annual meeting of the American Chemical Society (ACS), the largest scientific society in the world.

4 Apr 2017

Men with high levels of anabolic hormones less likely to develop worsening frailty, study suggests

A new study suggests that middle-age and elderly men are less likely to develop worsening frailty if they have high levels of certain anabolic hormones, which are muscle- and bone-building hormones.

3 Apr 2017

Researchers discover potential novel strategy for improving immunotherapy against cancer

Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered a potential novel strategy for improving drugs that unleash the immune system against cancer -- by binding two compounds to a nanoparticle.

3 Apr 2017

Researchers develop new technologies to measure key proteins that serve as markers for tumors

Dr. Amanda Paulovich, whose lab has a leading role in the Beau Biden Cancer Moonshot, will speak April 5 at the American Association for Cancer Research annual meeting about her lab's pioneering methods to measure proteins that serve as tumor markers.

3 Apr 2017

Immune System News and Research

Immunologists discover how rescue proteins delay ‘executioner’ machinery that kills damaged cells

Study of interactions between chemokines pinpoints potential targets for treatment of inflammation

Researchers uncover critical pathway that helps pancreatic cancer cells turn off immune system

Infection with reovirus could be key initiating event for developing celiac disease, study suggests

Cancer uses immature immune cells as support system for successful metastasis, study shows

Tumor necrosis factor may help control blood pressure, study suggests

Researchers solve medical mystery through genetics

Case Western Reserve University researchers aim to treat oral complications of HIV

Researchers develop stable brain implant based on anti-inflammatory coating

Experimental treatment cures Marburg and Ravn virus infection in animals

Researchers achieve new step towards treatment of myotubular myopathy using gene therapy

Probiotics may help treat yeast infections, bowel problems in men with schizophrenia

Number of HIV-positive cancer patients in the U.S. projected to decrease through 2030

Tumor microenvironment poses unique challenges for effective ovarian cancer T-cell therapy

Researchers discover possible new route to regenerating function lost in diabetes

Meningitis bacterium appears to be adapting to urogenital environment, DNA analysis shows

Global symposium focuses on chemistry and biological effects of maple food product

Men with high levels of anabolic hormones less likely to develop worsening frailty, study suggests

Researchers discover potential novel strategy for improving immunotherapy against cancer

Researchers develop new technologies to measure key proteins that serve as markers for tumors

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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