Infectious Diseases News and Research

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Kineta's next generation antiviral program receives $2.8 million NIH SBIR grant

Kineta, Inc. announced today its next generation antiviral program has received a 2.8 million dollar grant from the National Institute of Allergy and Infectious Disease, a part of the National Institutes of Health (NIH). Awarded under the Small Business Innovation Research (SBIR) program, the prestigious phase two grant will provide on-going support for Kineta's work on a new class of antiviral drugs targeting an array of global, deadly viruses.

12 Aug 2011

Advaxis completes ADXS-PSA prostate cancer construct pre-IND meeting with the FDA

Advaxis, Inc.,, a leader in developing the next generation of immunotherapies for cancer and infectious diseases, has completed a pre-IND (Investigational New Drug) meeting with the FDA on August 10 to discuss the development plan for ADXS-PSA, a construct for the treatment of prostate cancer.

12 Aug 2011

New technique can help develop HIV vaccines

Researchers have traced in detail how certain powerful HIV neutralizing antibodies evolve, a finding that generates vital clues to guide the design of a preventive HIV vaccine, according to a study appearing in Science Express this week.

12 Aug 2011

DYCAST software predicts spread of mosquito-borne West Nile virus in California counties

A computerized epidemiological model of the spread of the mosquito-borne West Nile virus in 17 counties of California in 2005 successfully predicted where 81.6 percent of human cases of the disease would arise and defined high-risk areas where the risk of infection turned out to be 39 times higher than in low-risk areas, according to newly published research.

12 Aug 2011

Researchers discover key reason why pyrazinamide shortens duration of TB therapy

Pyrazinamide has been used in combination with other drugs as a first-line treatment for people with tuberculosis (TB) since the 1950s, but exactly how the drug works has not been well understood.

12 Aug 2011

Researchers identify unknown link between migration of WBCs to infected tissues, immune memory

Researchers from Dr. Woodland's lab at the Trudeau Institute have now identified a previously unknown link between the migration of white blood cells to infected tissues and the ability of these cells to survive and become long-lived memory cells after the infection has been cleared.

11 Aug 2011

CDC Director lauds India for TB and tobacco use control efforts, urges preparations to fight NCDs

CDC Director Thomas Frieden, who currently is visiting India and who previously worked with the Indian government assisting in tuberculosis (TB) control, praised the country's "progress in controlling tuberculosis and tobacco use" on Monday during a speech to health practitioners and policymakers, according to the Wall Street Journal's "India Real Time" blog.

11 Aug 2011

Aeras, OETC announce initiation of new TB vaccine Phase IIb trial in patients with HIV

Aeras and the Oxford-Emergent Tuberculosis Consortium (OETC) announce today the start of a Phase IIb proof-of-concept efficacy trial of a new investigational tuberculosis (TB) vaccine that involves people living with the human immunodeficiency virus.

11 Aug 2011

Study finds very low rates of pertussis in children with cough

Contrary to some recent studies, only a low percentage of children treated for respiratory illness with cough have unsuspected pertussis, reports a study in the August issue of The Pediatric Infectious Disease Journal. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

10 Aug 2011

New report: U.S. antiseptics and disinfectants market to reach $2.9B by 2016

In 2009, the disinfectant and antiseptic market was worth around $3.4 billion, but by 2010 had grown over 12%, to reach a value of $3.8 billion, according to a new report available from companiesandmarkets.com.

9 Aug 2011

NIH awards Jefferson $4.8M grant to study vaccine to clear rabies virus from central nervous system

Thomas Jefferson University received a National Institutes of Health (NIH) $4.8 million grant to test a new rabies vaccine with the potential to cure the virus infection, even after it has made its way into a person's central nervous system (CNS). Today, if an unvaccinated person is infected with rabies and it spreads to the brain, there is little chance for survival.

8 Aug 2011

HPV-related throat cancer cases increase sharply over the past 10 years

Forty-two-year-old Manahawkin, New Jersey resident David Caldarella can recite a long list of dates off the top of his head. The first one starts with the day he found a lump on the right side of his neck while shaving. It was March 23, 2010. Caldarella immediately called his physician.

8 Aug 2011

Researchers discover lack of oxygen in the lungs after mold invasion

Researchers led by Montana State University have found a surprising condition that occurs in the lungs after an invasion of a common mold that can cause deadly infections in humans.

6 Aug 2011

Idera second quarter net loss increases to $6.3 million

Idera Pharmaceuticals, Inc. today reported financial results for the second quarter ended June 30, 2011. Idera is a biotechnology company engaged in the discovery and development of DNA- and RNA-based drug candidates targeted to Toll-Like receptors (TLRs).

5 Aug 2011

Clinical warning system that uses wireless sensors can track vital signs of at-risk patients

A clinical warning system that uses wireless sensors to track the vital signs of at-risk patients is undergoing a feasibility study at Barnes-Jewish Hospital in St. Louis.

5 Aug 2011

News media registration now open for ASM annual infectious diseases meeting

News media registration for the annual infectious diseases meeting of the American Society for Microbiology (ASM) is now open.

5 Aug 2011

Entomologist to study how immune system responds to rickettsial infection

Summer for most people means time spent outdoors, which could also mean increased exposure to bugs and, possibly, arthropod-borne diseases, such as "rickettsial diseases" - infectious diseases spread by bacteria, which, generally, are transmitted by lice, fleas, ticks and mites.

5 Aug 2011

New legislation allows physicians in Texas to treat chronic Lyme disease

Summertime, when kids and grown-ups abandon the confines of the indoors and head outside to camp, hike, fish and commune with nature -- and all of her friends. Flies, mosquitoes and ticks are just a few of the critters that go along with summer outdoors, and we all do our best to avoid the biting and stinging insects, but what happens if you are accosted by a tick? What are the myths behind Lyme disease and other tick-borne diseases in Texas?.

5 Aug 2011

Novel DNA sensing pathway linked to increased susceptibility to malaria

Scientists at the University of Massachusetts Medical School have uncovered a novel DNA-sensing pathway important to the triggering of an innate immune response for malaria. Activation of this pathway appears to stimulate production of an overabundance of type-1 interferon by the immune system that may contribute to inflammation and fever in malaria patients and could play a part in susceptibility for the most common and lethal form of malaria known as plasmodium falciparum.

5 Aug 2011

Virginia Tech student receives prestigious award for cellular signaling receptor study linked to diabetes, obesity

Stephanie Nicole "Nikki" Lewis, a graduate student in the interdisciplinary doctoral program in genetics, bioinformatics, and computational biology at Virginia Tech, has been awarded the prestigious Ruth L. Kirschstein National Research Service Award for Predoctoral Research through the National Institutes of Health for her study of a cellular signaling receptor that is associated with chronic inflammatory diseases such as diabetes, obesity, and inflammatory bowel disease.

5 Aug 2011

Infectious Diseases News and Research

Kineta's next generation antiviral program receives $2.8 million NIH SBIR grant

Advaxis completes ADXS-PSA prostate cancer construct pre-IND meeting with the FDA

New technique can help develop HIV vaccines

DYCAST software predicts spread of mosquito-borne West Nile virus in California counties

Researchers discover key reason why pyrazinamide shortens duration of TB therapy

Researchers identify unknown link between migration of WBCs to infected tissues, immune memory

CDC Director lauds India for TB and tobacco use control efforts, urges preparations to fight NCDs

Aeras, OETC announce initiation of new TB vaccine Phase IIb trial in patients with HIV

Study finds very low rates of pertussis in children with cough

New report: U.S. antiseptics and disinfectants market to reach $2.9B by 2016

NIH awards Jefferson $4.8M grant to study vaccine to clear rabies virus from central nervous system

HPV-related throat cancer cases increase sharply over the past 10 years

Researchers discover lack of oxygen in the lungs after mold invasion

Idera second quarter net loss increases to $6.3 million

Clinical warning system that uses wireless sensors can track vital signs of at-risk patients

News media registration now open for ASM annual infectious diseases meeting

Entomologist to study how immune system responds to rickettsial infection

New legislation allows physicians in Texas to treat chronic Lyme disease

Novel DNA sensing pathway linked to increased susceptibility to malaria

Virginia Tech student receives prestigious award for cellular signaling receptor study linked to diabetes, obesity

eBook: Advancing infectious disease vaccine development eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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