Therapy News and Research

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Light therapy may speed up the healing of burns by activating growth protein

Light therapy may accelerate the healing of burns, according to a University at Buffalo-led study.

6 Aug 2021

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Last year, University of Alabama at Birmingham researchers reported that reductive stress - an imbalance in the normal oxidation/reduction homeostasis - caused pathological changes associated with heart failure in a mouse model.

6 Aug 2021

Topical cream shows signs of clinical efficacy in patients with basal cell carcinoma

Remetinostat, a topical cream and first-in-class inhibitor of histone deacetylation, showed signs of clinical efficacy in patients with basal cell carcinoma.

6 Aug 2021

FDA approves an intravenous medication to treat patients with Pompe disease

Today, the U.S. Food and Drug Administration approved Nexviazyme (avalglucosidase alfa-ngpt) for intravenous infusion to treat patients 1 year of age and older with late-onset Pompe disease.

6 Aug 2021

Review highlights barriers to recruiting women into cardiovascular trials and offers solutions

Women must be equally represented in heart disease research to ensure that treatment recommendations meet their specific health needs, according to a report published today in European Heart Journal, a journal of the European Society of Cardiology (ESC).

6 Aug 2021

Using circulating tumor DNA to detect urothelial cancer relapse could help improve treatment

Using circulating tumor DNA to identify patients at risk of urothelial cancer relapse after surgical resection could help improve post-surgery treatment.

6 Aug 2021

Researchers create new model for studying earliest stages of retinoblastoma

Scientists at St. JudeChildren's Research Hospital have created a laboratory model for studying retinoblastoma driven by inherited mutations in theRB1gene.Retinoblastoma is a rare cancer of the retina, the thin tissue inside the back of the eye.

6 Aug 2021

Magnetic nanoparticles could enhance the efficacy of cancer immunotherapy

Boosting the function of natural killer cells with magnetic nanoparticles could make cancer immunotherapy more efficient.

6 Aug 2021

Full dose anticoagulation with heparin improves outcomes for moderately ill COVID-19 patients

Collaborative international clinical trials testing full dose anticoagulation with heparin (a blood thinner) in both moderately ill and critically ill patients has found the treatment improves outcomes and reduces the need for vital organ support such as mechanical ventilation in moderately ill patients.

6 Aug 2021

PD1 gene deletions associated with worse prognoses of cutaneous T-cell lymphomas

Immunohistochemistry staining showing PD1 expression on tumor cells in a skin biopsy from a cutaneous T-cell lymphoma patient.

5 Aug 2021

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

A new study has revealed the mechanism by which the SARS-CoV-2 N protein activates NLRP3 inflammasomes to induce hyperinflammation.

5 Aug 2021

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

Shuo Ma, MD, '00 PhD, associate professor of Medicine in the Division of Hematology and Oncology, was co-first author of the clinical trial published in Blood.

5 Aug 2021

Researchers develop the most comprehensive molecular map of lung squamous cell carcinoma

Lung cancer remains the leading cause of cancer-associated death in the United States and worldwide. Patients with a subtype called lung adenocarcinoma (LUAD) have benefited from the development of new targeted medicines, but the search for effective new therapies for another subtype called lung squamous cell carcinoma (LSCC) has largely come up short.

5 Aug 2021

UAB researchers identify potential therapeutic target for ovarian cancer

A gene called DOT1L appears to play a role in progression and severity of ovarian cancer, and inhibitors of the DOT1L enzyme may offer a new therapeutic approach for the disease, University of Alabama at Birmingham researchers say in a study published in the journal Oncogenesis.

5 Aug 2021

Mobile interventional stroke team travels to patients for providing faster access to surgical treatment

Stroke patients were almost twice as likely to be functionally independent - mobile and able to perform daily tasks - at 90 days post-stroke if they were treated by a specialized mobile stroke team that traveled to them to perform mechanical clot removal, compared to those who were transferred to a thrombectomy stroke center, according to research conducted within the Mount Sinai Health System and published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.

5 Aug 2021

Low glycemic diet results in important improvements for people with diabetes

For people with diabetes, sticking to a low glycemic diet results in small but important improvements in blood sugar levels, cholesterol, weight and other risk factors, finds a study published by The BMJ today.

5 Aug 2021

CHEST releases new clinical guidelines for management of venous thromboembolism

The American College of Chest Physicians recently released new clinical guidelines for venous thromboembolism management, "Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel," that provides 29 recommendations on 17 Patients, Interventions, Comparators, Outcomes (PICO) questions, four of which have not been addressed previously.

5 Aug 2021

Could a plant metabolite in liverworts be a potent antiviral against SARS-CoV-2 and other RNA viruses?

A new study from the National Centre for Biotechnology and Medicinal Chemistry Institute suggests Mother Nature delivered — in the form of liverworts. They found that the bryophyte Marchantia polymorpha, also known as umbrella liverworts, could work as a potential antiviral treatment.

5 Aug 2021

Post-COVID-19 neurological sequalae are not due to brain injury, study shows

In a recent study from University of Gothenburg, it has been shown that all participants achieve normalization of CNS injury biomarkers, regardless of previous disease severity or persistent neurological symptoms. Indicating that post-COVID-19 neurological sequalae are not due to active brain injury.

5 Aug 2021

Contingency management at end-of-treatment helps to overcome opioid use disorder

The opioid epidemic remains a U.S. public health crisis and has only worsened since the COVID-19 pandemic began in 2020, with opioid deaths accounting for 69,000 of 93,000 overdose-related deaths in 2020, according to provisional drug overdose data released by the U.S. Centers for Disease Control and Prevention in July 2021.

5 Aug 2021

Therapy News and Research

Light therapy may speed up the healing of burns by activating growth protein

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Topical cream shows signs of clinical efficacy in patients with basal cell carcinoma

FDA approves an intravenous medication to treat patients with Pompe disease

Review highlights barriers to recruiting women into cardiovascular trials and offers solutions

Using circulating tumor DNA to detect urothelial cancer relapse could help improve treatment

Researchers create new model for studying earliest stages of retinoblastoma

Magnetic nanoparticles could enhance the efficacy of cancer immunotherapy

Full dose anticoagulation with heparin improves outcomes for moderately ill COVID-19 patients

PD1 gene deletions associated with worse prognoses of cutaneous T-cell lymphomas

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

Researchers develop the most comprehensive molecular map of lung squamous cell carcinoma

UAB researchers identify potential therapeutic target for ovarian cancer

Mobile interventional stroke team travels to patients for providing faster access to surgical treatment

Low glycemic diet results in important improvements for people with diabetes

CHEST releases new clinical guidelines for management of venous thromboembolism

Could a plant metabolite in liverworts be a potent antiviral against SARS-CoV-2 and other RNA viruses?

Post-COVID-19 neurological sequalae are not due to brain injury, study shows

Contingency management at end-of-treatment helps to overcome opioid use disorder

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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