Clinical Trial News and Research

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Cancer Research UK, CRT partner with Asterias to trail novel immunotherapy treatment for lung cancer

CANCER RESEARCH UK and Cancer Research Technology , the charity's development and commercialisation arm, have reached an agreement with Asterias Biotherapeutics, Inc., a biotechnology company in the emerging field of regenerative medicine, to take forward Asterias' novel immunotherapy treatment AST-VAC2 into clinical trials in subjects with non-small cell lung cancer.

11 Sep 2014

AbbVie’s Phase 3 pivotal study shows HUMIRA is effective in reducing symptoms in HS

AbbVie today announced results from a Phase 3 pivotal study demonstrating that HUMIRA® (adalimumab) is effective in reducing common clinical signs and symptoms in moderate-to-severe hidradenitis suppurativa (HS), specifically the number of abscesses and inflammatory nodules.

11 Sep 2014

New book brings awareness to debate surrounding stem cell research

Mary Ann Liebert, Inc., leading publisher of over 80 science, technology, and medical publications, announced today the launch of first time hard cover title Inevitable Collision: The Inspiring Story that Brought Stem Cell Research to Conservative America, in an effort to bring awareness to the growing conversation and debate surrounding stem cell research and regenerative medicine.

11 Sep 2014

Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

Researchers at the University of California, San Diego School of Medicine, in partnership with ViaCyte, Inc., a San Diego-based biotechnology firm specializing in regenerative medicine, have launched the first-ever human Phase I/II clinical trial of a stem cell-derived therapy for patients with Type 1 diabetes.

11 Sep 2014

Dell, Terascala and TGen to install genomic data management solution at NCI

Dell, Terascala and the Translational Genomics Research Institute are installing state-of-the-art computing and programing specialized for human genome investigations at the National Cancer Institute.

10 Sep 2014

Researchers infuse antibody-studded iron nanoparticles into bloodstream to treat heart attack damage

Researchers at the Cedars-Sinai Heart Institute infused antibody-studded iron nanoparticles into the bloodstream to treat heart attack damage.

10 Sep 2014

New public resource to help researchers explore country-specific requirements

The National Institutes of Health (NIH) today launched ClinRegs, an online public database of country-specific clinical research regulatory information.

10 Sep 2014

Research shown to increase chances of babies surviving neonatal resuscitation

For several Edmonton parents, the work being done by University of Alberta researchers Po-Yin Cheung and Georg Schm-lzer could not be more meaningful.

9 Sep 2014

Experimental vaccine protects monkeys exposed to Ebola virus

One shot of an experimental vaccine made from two Ebola virus gene segments incorporated into a chimpanzee cold virus vector (called chimp adenovirus type 3 or ChAd3) protected all four macaque monkeys exposed to high levels of Ebola virus 5 weeks after inoculation, report National Institutes of Health (NIH) scientists and their collaborators.

9 Sep 2014

Mayo Clinic and IBM plan to pilot Watson to begin research studies in cancer

Mayo Clinic and IBM today announced plans to pilot Watson, the IBM cognitive computer, to match patients more quickly with appropriate clinical trials, beginning with research studies in cancer. A proof-of-concept phase is currently underway.

9 Sep 2014

Study ties eating in response to food cues to habit-forming region in obese adults

People who are obese may be more susceptible to environmental food cues than their lean counterparts due to differences in brain chemistry that make eating more habitual and less rewarding, according to a National Institutes of Health study published in Molecular Psychiatry.

9 Sep 2014

Treatment with xenon gas after head injury reduces extent of brain damage

Treatment with xenon gas after a head injury reduces the extent of brain damage, according to a study in mice.

9 Sep 2014

Agents targeting mitochondrial metabolism can have activity in leukemia

Results of a Phase I clinical trial showed that a new drug targeting mitochondrial function in human cancer cells was safe and showed some efficacy.

9 Sep 2014

New data from Boehringer's Phase III trial program evaluates efficacy of tiotropium in asthma patients

Boehringer Ingelheim today presented new data from the company's Phase III trial program (UniTinA-asthma®) evaluating tiotropium in asthma, including the first study assessing the efficacy and safety of tiotropium in adolescent patients with symptomatic asthma.

9 Sep 2014

New breast cancer vaccine provides evidence of immunotherapy in preventing disease recurrence

A new breast cancer vaccine candidate, (GP2), provides further evidence of the potential of immunotherapy in preventing disease recurrence. This is especially the case for high-risk patients when it is combined with a powerful immunotherapy drug.

8 Sep 2014

Transparency Life receives SBIR program grant to fund Phase 2a proof-of-concept study for MS

Transparency Life Sciences, LLC (TLS), the world's first clinical-stage drug development company based on open innovation, today announced that it has received a Small Business Innovation Research (SBIR) program grant to fund a Phase 2a proof-of-concept study testing the utility of the ACE inhibitor lisinopril as an adjunctive therapy for multiple sclerosis (MS).

8 Sep 2014

New antifungal drug effective against invasive mold disease in cancer patients with less adverse effects

A newly developed antifungal, isavuconazole, is as effective as an existing drug, voriconazole, against invasive mold disease in cancer patients with less adverse effects, according to phase 3 clinical data presented at the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy, an infectious disease meeting of the American Society for Microbiology.

8 Sep 2014

Soligenix acquires novel orphan drug candidate for treatment of CTCL

Soligenix, Inc., a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today the acquisition of a novel orphan drug candidate, known as SGX301 (synthetic hypericin).

8 Sep 2014

Scientists apply iPS cell technology to Huntington's disease transgenic monkey model

Creating induced pluripotent stem cells or iPS cells allows researchers to establish "disease in a dish" models of conditions ranging from Alzheimer's disease to diabetes.

8 Sep 2014

Study could lead to improvements in outcomes for women with triple-negative breast cancer

William M. Sikov, a medical oncologist in the Breast Health Center and associate director for clinical research in the Program in Women's Oncology at Women & Infants Hospital of Rhode Island, served as study chair and lead author for a recently-published major national study that could lead to improvements in outcomes for women with triple-negative breast cancer, an aggressive form of the disease that disproportionately affects younger women.

8 Sep 2014

Clinical Trial News and Research

Cancer Research UK, CRT partner with Asterias to trail novel immunotherapy treatment for lung cancer

AbbVie’s Phase 3 pivotal study shows HUMIRA is effective in reducing symptoms in HS

New book brings awareness to debate surrounding stem cell research

Clinical trial of stem cell-derived therapy for patients with Type 1 diabetes

Dell, Terascala and TGen to install genomic data management solution at NCI

Researchers infuse antibody-studded iron nanoparticles into bloodstream to treat heart attack damage

New public resource to help researchers explore country-specific requirements

Research shown to increase chances of babies surviving neonatal resuscitation

Experimental vaccine protects monkeys exposed to Ebola virus

Mayo Clinic and IBM plan to pilot Watson to begin research studies in cancer

Study ties eating in response to food cues to habit-forming region in obese adults

Treatment with xenon gas after head injury reduces extent of brain damage

Agents targeting mitochondrial metabolism can have activity in leukemia

New data from Boehringer's Phase III trial program evaluates efficacy of tiotropium in asthma patients

New breast cancer vaccine provides evidence of immunotherapy in preventing disease recurrence

Transparency Life receives SBIR program grant to fund Phase 2a proof-of-concept study for MS

New antifungal drug effective against invasive mold disease in cancer patients with less adverse effects

Soligenix acquires novel orphan drug candidate for treatment of CTCL

Scientists apply iPS cell technology to Huntington's disease transgenic monkey model

Study could lead to improvements in outcomes for women with triple-negative breast cancer

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