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Scientists seek Covid treatment answers in cheap, older drugs

Could a decades-old antidepressant be a secret weapon against covid? A few scientists think so, after two small studies showed that fluvoxamine, typically prescribed for obsessive-compulsive disorder, prevented serious illness in all participants who took the pills soon after developing symptoms.

29 Mar 2021

Developing orally administrable drugs to combat SARS-CoV-2

Researchers in China have reported the successful design and synthesis of two antiviral compounds that target the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)’s main protease, essential in virus replication.

29 Mar 2021

Albumedix announces recombinant human albumin supply partnership with FUJIFILM Wako Pure Chemical Corporation for the Japanese, Chinese and Hong Kong markets

Albumedix Ltd. (‘Albumedix’), an enabler of advanced therapies and world leader in recombinant human albumin (rHA), announced today that they have entered into a distribution agreement with established and well recognized reagent supplier FUJIFILM Wako Pure Chemical Corporation (FUJIFILM Wako) in Japan and China including Hong Kong.

From Albumedix Ltd. 29 Mar 2021

New study provides the most comprehensive reviews of advancements in contact lenses

A newly-published paper represents one of the most comprehensive reviews of advancements to come in contact lenses, catapulting the commonly-used medical device to applications well beyond refractive error correction.

29 Mar 2021

First cell-based gene therapy approved by the FDA for treating multiple myeloma

The U.S. Food and Drug Administration approved Abecma (idecabtagene vicleucel), a cell-based gene therapy to treat adult patients with multiple myeloma who have not responded to, or whose disease has returned after, at least four prior lines (different types) of therapy.

29 Mar 2021

Boerhavia diffusa possess potential therapeutic properties against COVID-19

Several companies and research groups have been searching for suitably docking ligands that inhibit the function of this protein. In a research paper recently published to the Springer journal VirusDisease by Surya & Praveen (March 6th, 2021) in silico docking simulations towards 3CLpro have been performed, focusing in particular on natural products obtained from the plant Boerhavia diffusa.

28 Mar 2021

Selecting SARS-CoV-2 inhibitors in human airway epithelial cells

In a recent article currently available on the bioRxiv* preprint server, researchers from Belgium and the U.S. demonstrated a robust replication model for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolates in primary human epithelial cells at the air-liquid interface and appraised the antiviral effect of selected viral replication inhibitors.

28 Mar 2021

Researchers identify new drug candidates for treating patients with severe COVID-19

University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2--the virus that causes COVID-19 - and then used an FDA-approved cancer drug to blunt the viral protein's detrimental effects.

27 Mar 2021

FDA acknowledged receipt of ORNL’s cancer-fighting Ac-225 isotope

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

27 Mar 2021

Novel molecule could offer a new way to fight against SARS coronavirus 2

Scientists at the University of Bonn and the caesar research center have isolated a molecule that might open new avenues in the fight against SARS coronavirus 2. The active ingredient binds to the spike protein that the virus uses to dock to the cells it infects.

27 Mar 2021

Using molecular ‘cookie cutters’ to isolate first ever COVID-19 encounter complex

University of Birmingham researchers are working to isolate and extract the COVID-19 encounter complex in a form that is stable enough for identification of target sites for future anti-viral drugs.

27 Mar 2021

Researchers identify neural circuit involved in reciprocally regulating weight gain and depression

Research has found that obesity and mental disorders such as depression and anxiety seem to often go hand in hand.

26 Mar 2021

IQWiG releases revised version of its General Methods

The Institute for Quality and Efficiency in Health Care (IQWiG) revised its methods paper and published the German original version "Allgemeine Methoden 6.0" (General Methods 6.0) on http://www.iqwig.de in November 2020.

26 Mar 2021

Salk joins a long list of recipients included in The Conrad Prebys Foundation’s inaugural grant cycle

Salk Professor Thomas Albright has been awarded $1 million and Assistant Professor Edward Stites awarded $500,000 by The Conrad Prebys Foundation as part of its inaugural round of grants.

26 Mar 2021

POSTECH researchers produce artificial lung model using 3D printing

The warmer temperature and blooming flowers signal the arrival of spring. However, worries about respiratory diseases are also on the rise due to fine dust and viruses.

26 Mar 2021

FDA authorizes marketing of new device for short-term treatment of gait deficit in MS patients

Today, the U.S. Food and Drug Administration authorized marketing of a new device indicated for use as a short-term treatment of gait deficit due to mild to moderate symptoms from multiple sclerosis (MS).

26 Mar 2021

FDA approves non-surgical heart valve to treat patients with certain types of congenital heart disease

Today, the U.S. Food and Drug Administration approved the first in the world non-surgical heart valve to treat pediatric and adult patients with a native or surgically-repaired right ventricular outflow tract (RVOT), the part of the heart that carries blood out of the right ventricle to the lungs.

26 Mar 2021

‘Incredibly concerning’ lawsuit threatens no-charge preventive care for millions

With a challenge to the Affordable Care Act still pending at the Supreme Court, conservatives are continuing to launch legal attacks on the law, including a case in which a Texas federal judge seems open to ending the requirement that most Americans must receive preventive services like mammograms free of charge.

26 Mar 2021

Scientists identify new genetic clues to treat “silent’ stroke

Scientists have identified new genetic clues in people who've had small and often apparently 'silent' strokes that are difficult to treat and a major cause of vascular dementia, according to research funded by the British Heart Foundation (BHF) and published in The Lancet Neurology.

26 Mar 2021

Chemists successfully convert flat nitrogen-containing molecules into 3D structures

A major goal of organic and medicinal chemistry in recent decades has been the rapid synthesis of three-dimensional molecules for the development of new drugs.

26 Mar 2021

Drugs News and Research

Scientists seek Covid treatment answers in cheap, older drugs

Developing orally administrable drugs to combat SARS-CoV-2

Albumedix announces recombinant human albumin supply partnership with FUJIFILM Wako Pure Chemical Corporation for the Japanese, Chinese and Hong Kong markets

New study provides the most comprehensive reviews of advancements in contact lenses

First cell-based gene therapy approved by the FDA for treating multiple myeloma

Boerhavia diffusa possess potential therapeutic properties against COVID-19

Selecting SARS-CoV-2 inhibitors in human airway epithelial cells

Researchers identify new drug candidates for treating patients with severe COVID-19

FDA acknowledged receipt of ORNL’s cancer-fighting Ac-225 isotope

Novel molecule could offer a new way to fight against SARS coronavirus 2

Using molecular ‘cookie cutters’ to isolate first ever COVID-19 encounter complex

Researchers identify neural circuit involved in reciprocally regulating weight gain and depression

IQWiG releases revised version of its General Methods

Salk joins a long list of recipients included in The Conrad Prebys Foundation’s inaugural grant cycle

POSTECH researchers produce artificial lung model using 3D printing

FDA authorizes marketing of new device for short-term treatment of gait deficit in MS patients

FDA approves non-surgical heart valve to treat patients with certain types of congenital heart disease

‘Incredibly concerning’ lawsuit threatens no-charge preventive care for millions

Scientists identify new genetic clues to treat “silent’ stroke

Chemists successfully convert flat nitrogen-containing molecules into 3D structures

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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