Immune System News and Research

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New antibody test can detect person’s risk for developing HPV-related cancer of the oropharynx

Cancer of the oropharynx has become increasingly common: In the United States alone, the number of newly diagnosed cases has tripled over the past three decades. About 70 percent of these tumors are caused by infection with human papillomavirus (HPV) type 16.

3 Apr 2017

Researchers shed light on how immune cells weaken with age

Researchers from the European Bioinformatics Institute, University of Cambridge, the Wellcome Trust Sanger Institute and the Cancer Research UK–Cambridge Institute have shed light on a long-standing debate about why the immune system weakens with age.

3 Apr 2017

Patients' immune system profiles could be linked to effectiveness of cancer immunotherapy

Higher or lower levels of certain immune cells in cancer patients may be associated with how well they respond to immunotherapy, according to preliminary results of a study conducted by researchers at the University of Pittsburgh Cancer Institute.

3 Apr 2017

Amgen, UCB present romosozumab Phase 2 results at ENDO 2017

Amgen and UCB today announced results from the fourth year of a Phase 2 study showing the efficacy and safety of a second course of treatment with EVENITY™* (romosozumab), an investigational agent for postmenopausal women with osteoporosis.

3 Apr 2017

University of Miami to begin clinical trial for testing DNA-based Zika vaccine

The University of Miami Miller School of Medicine will soon begin one of the nation's first full-scale Zika vaccine clinical trials testing the National Institutes of Health's (NIH) experimental DNA-based vaccine.

31 Mar 2017

Investigational compound for treating indolent lymphomas shows positive results in phase II clinical study

Bayer today announced positive data on its investigational compound copanlisib, an intravenous pan-Class I phosphatidylinositol-3-kinase (PI3K) inhibitor with predominant inhibitory activity against PI3K-α and PI3K-δ isoforms.

31 Mar 2017

Case Western Reserve and Q2 Pharma partner to develop antivirulence agents that disarm superbugs

Case Western Reserve University and Q2 Pharma Ltd., an Israeli biopharmaceutical company, have signed a two-year option to license small molecule, antivirulence technology to potentially treat bacterial infections such as methicillin-resistant staphylococcus aureus (MRSA), the first known scientific effort of its kind.

31 Mar 2017

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

Vaccinations have begun in a multi-site Phase 2/2b clinical trial testing an experimental DNA vaccine designed to protect against disease caused by Zika infection.

31 Mar 2017

Study shows new treatment pathway for antibiotic resistant bacteria and infectious diseases

A study, published in the American Journal of Respiratory and Critical Care Medicine, describes a new treatment pathway for antibiotic resistant bacteria and infectious diseases with benefits for patients and health care providers.

31 Mar 2017

Novel Research Grants bring new insight to complexities of lupus

The Lupus Research Alliance announced today the Novel Research Grant Class of 2017. The Lupus Research Alliance Novel Research Grants, the proven platform for innovation, make discovery and scientific progress possible.

30 Mar 2017

Researchers discover how epigenetic lesion can lead to T-cell acute lymphoblastic leukemia

Researchers from the Epigenetics and Cancer Biology Program led by Dr. Manel Esteller at the Bellvitge Biomedical Research Institute have discovered how an epigenetic lesion can lead to T-cell acute lymphoblastic leukemia.

30 Mar 2017

Fruit flies genetically coded to take frequent naps have higher resistance to dangerous superbugs

A new University of Maryland study has found that fruit flies genetically coded to take frequent naps had the strongest resistance to both a fungal infection and to a bacteria that the World Health Organization says is one of the world's most dangerous superbugs for humans.

30 Mar 2017

Researchers propose novel theory of how some cancers circumvent killing power of targeted therapies

Nearly 50 years into the "war" on cancer, doctors possess weapons that once would have seemed magical in their tumor-killing specificity.

29 Mar 2017

Endocannabinoid system stimulation may be potential approach to treatment of epilepsy, study shows

In a study published in Brain Research, biophysicists from the Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences and MIPT have shown that drug-induced activation of the endocannabinoid system of the brain leads to reduced or completely suppressed epileptic activity in test animals.

29 Mar 2017

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

All causes of the most common form of liver cancer, hepatocellular carcinoma, are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.

29 Mar 2017

Research sheds new light on reasons behind recurrent aphthous stomatitis

A burning pain sensation - and treatments that do not work. This is what daily life is like for many of those who suffer from recurrent aphthous stomatitis. Research from the Sahlgrenska Academy now sheds new light on the reasons behind this condition found in the mouth.

29 Mar 2017

Study explores new immunotherapy combinations to treat prostate cancer

Prostate cancer, notoriously resistant to immunotherapy due to its immunologically cool nature, triggers two pathways to chill an immune attack after one immunotherapy drug fires up the immune system, researchers at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

29 Mar 2017

TSRI researchers reveal how viruses incapacitate bacterial defense system

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas.

28 Mar 2017

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

HIV is a master of disguise. The virus uses a shield of sugar molecules, called glycans, to hide from the immune system and block antibodies from attacking it.

28 Mar 2017

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, will highlight a variety of basic research and population studies at the annual meeting of the American Association for Cancer Research at the Walter E. Washington Convention Center in Washington, D.C., April 1 to 5.

28 Mar 2017

Immune System News and Research

New antibody test can detect person’s risk for developing HPV-related cancer of the oropharynx

Researchers shed light on how immune cells weaken with age

Patients' immune system profiles could be linked to effectiveness of cancer immunotherapy

Amgen, UCB present romosozumab Phase 2 results at ENDO 2017

University of Miami to begin clinical trial for testing DNA-based Zika vaccine

Investigational compound for treating indolent lymphomas shows positive results in phase II clinical study

Case Western Reserve and Q2 Pharma partner to develop antivirulence agents that disarm superbugs

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

Study shows new treatment pathway for antibiotic resistant bacteria and infectious diseases

Novel Research Grants bring new insight to complexities of lupus

Researchers discover how epigenetic lesion can lead to T-cell acute lymphoblastic leukemia

Fruit flies genetically coded to take frequent naps have higher resistance to dangerous superbugs

Researchers propose novel theory of how some cancers circumvent killing power of targeted therapies

Endocannabinoid system stimulation may be potential approach to treatment of epilepsy, study shows

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

Research sheds new light on reasons behind recurrent aphthous stomatitis

Study explores new immunotherapy combinations to treat prostate cancer

TSRI researchers reveal how viruses incapacitate bacterial defense system

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

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